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Apolipoproteins and aging: emerging mechanisms
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
12067591
retrieved
3 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
Apolipoproteins and aging: emerging mechanisms
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
12067591
retrieved
3 August 2017
author name string
Jonathan D Smith
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
12067591
retrieved
3 August 2017
publication date
1 June 2002
1 reference
stated in
Europe PubMed Central
PubMed ID
12067591
retrieved
3 August 2017
published in
Ageing Research Reviews
1 reference
stated in
Europe PubMed Central
PubMed ID
12067591
retrieved
3 August 2017
volume
1
1 reference
stated in
Europe PubMed Central
PubMed ID
12067591
retrieved
3 August 2017
issue
3
1 reference
stated in
Europe PubMed Central
PubMed ID
12067591
retrieved
3 August 2017
page(s)
345-365
1 reference
stated in
Europe PubMed Central
PubMed ID
12067591
retrieved
3 August 2017
cites work
Severity of cardiovascular disease, apolipoprotein E genotype, and brain pathology in aging and dementia
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Apolipoprotein E polymorphism is not associated with longevity or disability in a sample of Italian octo- and nonagenarians.
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Crossref
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Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition.
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Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease
1 reference
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7 January 2021
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Isoform-specific modulation by apolipoprotein E of the activities of secreted beta-amyloid precursor protein.
1 reference
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Crossref
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7 January 2021
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Apo E influences declarative and procedural learning in age-associated memory impairment.
1 reference
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Early effect of ApoE-epsilon 4 allele on cognitive results in a group of highly performing subjects: the EVA study. Etude sur le Vieillissement Artériel.
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Rapid induction of intraneuronal neurofibrillary tangles in apolipoprotein E-deficient mice
1 reference
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7 January 2021
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Co-expression of beta-amyloid precursor protein (betaAPP) and apolipoprotein E in cell culture: analysis of betaAPP processing
1 reference
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7 January 2021
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ApoE-4 and age at onset of Alzheimer's disease: the NIMH genetics initiative.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
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7 January 2021
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inferred from DOI database lookup
A study of French centenarians: are ACE and APOE associated with longevity?
1 reference
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Crossref
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7 January 2021
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Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins.
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system
1 reference
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Crossref
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7 January 2021
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A polymorphism in the regulatory region of APOE associated with risk for Alzheimer's dementia.
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7 January 2021
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Human apolipoprotein E4 accelerates beta-amyloid deposition in APPsw transgenic mouse brain.
1 reference
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Crossref
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7 January 2021
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Preclinical cognitive decline in late middle-aged asymptomatic apolipoprotein E-e4/4 homozygotes: a replication study.
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: differential effects of APOE genotype and presenilin mutations
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
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7 January 2021
based on heuristic
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Apo E allele frequencies in younger (age 42-50) vs older (age 65-90) women
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
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7 January 2021
based on heuristic
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Apolipoprotein E Polymorphism: A New Genetic Marker of Hip Fracture RiskThe Study of Osteoporotic Fractures
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Age-related cognitive decline, mild cognitive impairment or preclinical Alzheimer's disease?
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of apolipoprotein E genotype on hippocampal volume loss in aging healthy women.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Memory decline in healthy older people: implications for identifying mild cognitive impairment.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
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7 January 2021
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inferred from DOI database lookup
Apolipoprotein E genotype determines survival in the oldest old (85 years or older) who have good cognition.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Accelerated decline in apolipoprotein E-epsilon4 homozygotes with Alzheimer's disease.
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
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Apolipoprotein E polymorphism and atherosclerosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
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7 January 2021
based on heuristic
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Prediction of cognitive decline in normal elderly subjects with 2-[(18)F]fluoro-2-deoxy-D-glucose/positron-emission tomography (FDG/PET).
1 reference
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Crossref
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7 January 2021
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Cerebrovascular and brain morphologic correlates of mild cognitive impairment in the National Heart, Lung, and Blood Institute Twin Study
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https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
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7 January 2021
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The endosomal trafficking of apolipoprotein E3 and E4 in cultured human brain neurons and astrocytes
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Stroke and apolipoprotein E epsilon4 are independent risk factors for cognitive decline: A population-based study.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Memory complaints and APOE-epsilon4 accelerate cognitive decline in cognitively normal elderly
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of the apolipoprotein E and CI loci in predisposing to late-onset Alzheimer's disease.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Amyloid-beta peptide-receptor for advanced glycation endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: a proinflammatory pathway in Alzheimer disease
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Microglial activation in Alzheimer disease: Association with APOE genotype.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
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7 January 2021
based on heuristic
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Polymorphisms of the apolipoprotein B and E genes and their relationship to plasma lipid variables in healthy Chinese men
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
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7 January 2021
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Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The relationship of APOE genotype to cognitive functioning in older African-American and Caucasian community residents.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential binding of apolipoprotein E isoforms to tau and other cytoskeletal proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Longevity and the epsilon2 allele of apolipoprotein E: the Finnish Centenarians Study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of the apo E/apo C-I, angiotensin converting enzyme and methylenetetrahydrofolate reductase genes as candidates affecting human longevity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Estimation of apolipoprotein E genotype-specific relative mortality risks from the distribution of genotypes in centenarians and middle-aged men: apolipoprotein E gene is a "frailty gene," not a "longevity gene"
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clinical and pathological correlates of apolipoprotein E ?4 in Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetics and visual attention: selective deficits in healthy adult carriers of the epsilon 4 allele of the apolipoprotein E gene
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E genotype does not influence rates of cognitive decline in Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Head injury and the risk of AD in the MIRAGE study
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of APOE epsilon4 in modulating effects of other risk factors for cognitive decline in elderly persons
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Behavioral phenotyping of GFAP-apoE3 and -apoE4 transgenic mice: apoE4 mice show profound working memory impairments in the absence of Alzheimer's-like neuropathology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuronal apoptosis by apolipoprotein E4 through low-density lipoprotein receptor-related protein and heterotrimeric GTPases.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Memory functions in human subjects with different apolipoprotein E phenotypes during a 3-year population-based follow-up study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The heritability of human longevity: A population-based study of 2872 Danish twin pairs born 1870–1900
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
[Tokyo Centenarian Study. 4. Apolipoprotein E phenotype in Japanese centenarians living in the Tokyo Metropolitan area]
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Single photon emission computed tomography and apolipoprotein E in Alzheimer's disease: impact of the epsilon4 allele on regional cerebral blood flow.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E: non-cognitive symptoms and cognitive decline in late onset Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of human apolipoprotein E reduces amyloid-beta deposition in a mouse model of Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of apolipoprotein E in Alzheimer's disease, acute brain injury and cerebrovascular disease: evidence of common mechanisms and utility of animal models
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of apolipoprotein E phenotype with plasma lipoproteins in African-American and white young adults. The CARDIA Study. Coronary Artery Risk Development in Young Adults
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E attenuates beta-amyloid-induced astrocyte activation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of apolipoprotein E with laminin increases neuronal adhesion and alters neurite morphology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Quantitative analysis of senile plaques in Alzheimer disease: observation of log-normal size distribution and molecular epidemiology of differences associated with apolipoprotein E genotype and trisomy 21 (Down syndrome).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of the low-density lipoprotein receptor-related protein in beta-amyloid metabolism and Alzheimer disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Age-dependent association of apolipoprotein E genotype with coronary and aortic atherosclerosis in middle-aged men: an autopsy study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E polymorphism and carotid artery intima-media thickness in a random sample of middle-aged men
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E affects the amount, form, and anatomical distribution of amyloid beta-peptide deposition in homozygous APP(V717F) transgenic mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E and longevity among Han Chinese population.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A full genome scan for late onset Alzheimer's disease.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E and B polymorphisms--longevity factors assessed in nonagenarians
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intestinal cholesterol absorption efficiency in man is related to apoprotein E phenotype
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Changes of genetic apolipoprotein phenotypes caused by liver transplantation. Implications for apolipoprotein synthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E4 phenotype is not an important risk factor for coronary heart disease or stroke in elderly subjects
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Purification of apolipoprotein E attenuates isoform-specific binding to beta-amyloid
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E genotype and cardiovascular disease in the Framingham Heart Study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pronounced impact of Th1/E47cs mutation compared with -491 AT mutation on neural APOE gene expression and risk of developing Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Risk of dementia among relatives of Alzheimer's disease patients in the MIRAGE study: What is in store for the oldest old?
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mortality and apolipoprotein E in Hispanic, African-American, and Caucasian elders
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
How does the apolipoprotein E genotype modulate the brain in aging and in Alzheimer's disease? A review of neuroimaging studies
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hyper-expression of human apolipoprotein E4 in astroglia and neurons does not enhance amyloid deposition in transgenic mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aging and genetic variation of plasma apolipoproteins. Relative loss of the apolipoprotein E4 phenotype in centenarians
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E: cholesterol transport protein with expanding role in cell biology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E: from atherosclerosis to Alzheimer's disease and beyond
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Memory performance in healthy elderly without Alzheimer's disease: effects of time and apolipoprotein-E.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
APOE genotype as a risk factor for ischemic cerebrovascular disease: a meta-analysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Head trauma and risk of dementia and Alzheimer's disease: The Rotterdam Study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Longitudinal change in hippocampal volume as a function of apolipoprotein E genotype.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential effects of apolipoprotein E isoforms on metal-induced aggregation of A beta using physiological concentrations.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased cerebral cortical lipid peroxidation and abnormal phospholipids in aged homozygous apoE-deficient C57BL/6J mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A gender difference in the association between APOE genotype and age-related cognitive decline
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E protects against neuropathology induced by a high-fat diet and maintains the integrity of the blood-brain barrier during aging.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E status is associated with odor identification deficits in nondemented older persons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of stable complexes involving apolipoprotein E and the amyloid beta peptide in Alzheimer's disease brain.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The APOE epsilon4 allele is associated with decline on delayed recall performance in community-dwelling older adults
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E isoforms and the development of low and high Braak stages of Alzheimer's disease-related lesions.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mechanism for the neuroprotective effect of apolipoprotein E: isoform-specific modification by the lipid peroxidation product 4-hydroxynonenal
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Centenarians prove the compression of morbidity hypothesis, but what about the rest of us who are genetically less fortunate?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Siblings of centenarians live longer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Current concepts in mild cognitive impairment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E genotype and amyloid load in Alzheimer disease and control brains.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E, Dementia, and Cortical Deposition of β-Amyloid Protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Brains of aged apolipoprotein E-deficient mice have increased levels of F2-isoprostanes, in vivo markers of lipid peroxidation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A genome-wide scan for linkage to human exceptional longevity identifies a locus on chromosome 4.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxidative damage and protection by antioxidants in the frontal cortex of Alzheimer's disease is related to the apolipoprotein E genotype.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E alleles in nonagenarian subjects in the Belfast Elderly Longitudinal Free-living Ageing Study (BELFAST)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduced apolipoprotein epsilon 4 allele frequency in the oldest old Alzheimer's patients and cognitively normal individuals.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cognitive function and apolipoprotein E in very old adults: findings from the Nun Study.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E genetic variation and Alzheimer's disease. a meta-analysis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Susceptibility of transgenic mice expressing human apolipoprotein E to closed head injury: the allele E3 is neuroprotective whereas E4 increases fatalities.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic associations with human longevity at the APOE and ACE loci.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E polymorphism: survival and neurological outcome after cardiopulmonary resuscitation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human apolipoprotein E accelerates microtubule polymerization in vitro.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Duplicated downstream enhancers control expression of the human apolipoprotein E gene in macrophages and adipose tissue
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distribution of geriatric disease-related genotypes in the National Institute for Longevity Sciences, Longitudinal Study of Aging (NILS-LSA)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The effect of APOE on dementia is not through atherosclerosis: the Rotterdam Study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E genotype and progression of Alzheimer's disease: the Rotterdam Study.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Is APOE--epsilon4 a risk factor for cognitive impairment in normal aging?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E polymorphism in The Netherlands and its effect on plasma lipid and apolipoprotein levels
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E4: an allele associated with many diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E genotype influences cognitive 'phenotype' in patients with Alzheimer's disease but not in healthy control subjects.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human apolipoprotein E allele-specific brain expressing transgenic mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E genotypes and cognitive functions in healthy elderly persons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E polymorphism predicts death from coronary heart disease in a longitudinal study of elderly Finnish men
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An ecological study of association between coronary heart disease mortality rates in men and the relative frequencies of common allelic variations in the gene coding for apolipoprotein E.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E genotype, vascular risk and early cognitive impairment in an African Caribbean population
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E phenotype regulates cholesterol absorption in healthy 13-month-old children--The STRIP Study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The APOE-epsilon4 allele and the risk of Alzheimer disease among African Americans, whites, and Hispanics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Incidence of AD in African-Americans, Caribbean Hispanics, and Caucasians in northern Manhattan.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Preliminary report of a genetic basis for cognitive decline after cardiac operations. The Neurologic Outcome Research Group of the Duke Heart Center.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein tau in the brains of transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human apolipoprotein E isoform-specific differences in neuronal sprouting in organotypic hippocampal culture
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid beta peptides
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E phenotypes in demented and cognitively impaired patients with and without cerebrovascular disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
No association between apolipoprotein E polymorphisms and general cognitive ability in children.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Astrocytes down-regulate neuronal beta-amyloid precursor protein expression and modify its processing in an apolipoprotein E isoform-specific manner.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Osteoporosis and apolipoprotein E genotype in older adults: the Rancho Bernardo study.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E4 promotes incipient Alzheimer pathology in the elderly.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E Alleles and Risk of Coronary Disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alzheimer beta amyloid deposition enhanced by apoE epsilon4 gene precedes neurofibrillary pathology in the frontal association cortex of nondemented senior subjects.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E promotes the binding and uptake of beta-amyloid into Chinese hamster ovary cells in an isoform-specific manner
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intelligence and event-related potentials for young female human volunteer apolipoprotein E epsilon4 and non-epsilon4 carriers.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Three-year changes in cognitive performance as a function of apolipoprotein E genotype: evidence from very old adults without dementia.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900005-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1568-1637(02)00005-3
1 reference
stated in
Europe PubMed Central
PubMed ID
12067591
retrieved
3 August 2017
PubMed ID
12067591
1 reference
stated in
Europe PubMed Central
PubMed ID
12067591
retrieved
3 August 2017
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