(Q34695396)

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Expression of tryptophan 2,3-dioxygenase and production of kynurenine pathway metabolites in triple transgenic mice and human Alzheimer's disease brain

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scholarly article

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Europe PubMed Central

PubMed publication ID

4 August 2017

Expression of tryptophan 2,3-dioxygenase and production of kynurenine pathway metabolites in triple transgenic mice and human Alzheimer's disease brain (English)

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Europe PubMed Central

PubMed publication ID

4 August 2017

Alzheimer's disease

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ChEBI release 2020-05-28

8

object named as

Bruce J Brew

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Europe PubMed Central

PubMed publication ID

4 August 2017

author name string

Wei Wu

1

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Joseph A Nicolazzo

2

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Europe PubMed Central

PubMed publication ID

4 August 2017

Li Wen

3

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Roger Chung

4

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Roger Stankovic

5

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Shisan S Bao

6

1 reference

Europe PubMed Central

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4 August 2017

Chai K Lim

7

1 reference

Europe PubMed Central

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4 August 2017

Karen M Cullen

9

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4 August 2017

Gilles J Guillemin

10

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4 August 2017

language of work or name

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publication date

22 April 2013

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Europe PubMed Central

PubMed publication ID

4 August 2017

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Europe PubMed Central

PubMed publication ID

4 August 2017

8

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Europe PubMed Central

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4 August 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

e59749

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

copyright license

Creative Commons Attribution 4.0 International

22 April 2013

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April 2022 Public Data File from Crossref

copyright status

0 references

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1 reference

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Quinolinic acid, the inescapable neurotoxin

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Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration

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Expression of tryptophan 2,3-dioxygenase in mature granule cells of the adult mouse dentate gyrus.

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Interferon-gamma-inducible kynurenines/pteridines inflammation cascade: implications for aging and aging-associated psychiatric and medical disorders

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7 July 2018

Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease

1 reference

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7 July 2018

The excitotoxin quinolinic acid induces tau phosphorylation in human neurons

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Proinflammatory cytokine interferon-gamma increases induction of indoleamine 2,3-dioxygenase in monocytic cells primed with amyloid beta peptide 1-42: implications for the pathogenesis of Alzheimer's disease

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Highlights at the gate of tryptophan catabolism: a review on the mechanisms of activation and regulation of indoleamine 2,3-dioxygenase (IDO), a novel target in cancer disease

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Levo- but not dextro-1-methyl tryptophan abrogates the IDO activity of human dendritic cells

1 reference

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Characterization of the kynurenine pathway in human neurons

1 reference

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7 July 2018

Tryptophan metabolism in the central nervous system: medical implications

1 reference

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Biochemical and medical aspects of the indoleamine 2,3-dioxygenase-initiated L-tryptophan metabolism

1 reference

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7 July 2018

Indoleamine 2,3 dioxygenase and quinolinic acid immunoreactivity in Alzheimer's disease hippocampus

1 reference

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Expression of indoleamine 2,3-dioxygenase and production of quinolinic acid by human microglia, astrocytes, and neurons

1 reference

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Identification and expression of alpha cDNA encoding human 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (ACMSD): a key enzyme for the tryptophan-niacine pathway and quinolinate hypothesis

1 reference

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Expression of the kynurenine pathway enzymes in human microglia and macrophages

2 references

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7 July 2018

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21 January 2018

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

1 reference

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Local neuroinflammation and the progression of Alzheimer's disease

1 reference

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Indoleamine 2,3-dioxygenase, immunosuppression and pregnancy

1 reference

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The tryptophan catabolite picolinic acid selectively induces the chemokines macrophage inflammatory protein-1 alpha and -1 beta in macrophages

1 reference

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Inhibition of T cell proliferation by macrophage tryptophan catabolism

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Different kynurenine pathway enzymes limit quinolinic acid formation by various human cell types

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Immunobiology of picolinic acid.

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Regulation of the kynurenine metabolic pathway by interferon-gamma in murine cloned macrophages and microglial cells.

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Mechanism of interferon-gamma action. Characterization of indoleamine 2,3-dioxygenase in cultured human cells induced by interferon-gamma and evaluation of the enzyme-mediated tryptophan degradation in its anticellular activity.

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Quinolinate-induced cortical cholinergic damage: modulation by tryptophan metabolites.

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Expression of the kynurenine pathway enzyme tryptophan 2,3-dioxygenase is increased in the frontal cortex of individuals with schizophrenia

1 reference

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Neuronal localization of indoleamine 2,3-dioxygenase in mice

1 reference

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Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection

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1 reference

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Activated human microglia produce the excitotoxin quinolinic acid

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https://pubmed.ncbi.nlm.nih.gov/23630570

12 December 2020

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inferred from PubMed ID database lookup

Adrenal cortical activity changes in manic-depressive illness. Influence on intermediary metabolism of tryptophan

1 reference

https://pubmed.ncbi.nlm.nih.gov/23630570

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inferred from PubMed ID database lookup

Tryptophan metabolism through the kynurenine pathway in rat brain and liver slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/23630570

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based on heuristic

inferred from PubMed ID database lookup

The oxygenated form of L-tryptophan 2,3-dioxygenase as reaction intermediate

1 reference

https://pubmed.ncbi.nlm.nih.gov/23630570

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based on heuristic

inferred from PubMed ID database lookup

Picolinic acid modulates kainic acid-evoked glutamate release from the striatum in vitro

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0059749

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

2013PLoSO...859749W

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

ResearchGate publication ID

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