(Q34695506)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23630590%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

Molecular ageing of alpha- and Beta-synucleins: protein damage and repair mechanisms (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23630590%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23630590%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Wayne Carter

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23630590%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

author name string

Vasanthy Vigneswara

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23630590%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Simon Cass

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23630590%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Declan Wayne

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23630590%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

David E Ray

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23630590%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

language of work or name

English

0 references

publication date

22 April 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23630590%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23630590%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23630590%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23630590%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

page(s)

e61442

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23630590%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

29 February 2020

copyright license

start time

22 April 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Inhibiting α-synuclein oligomerization by stable cell-penetrating β-synuclein fragments recovers phenotype of Parkinson's disease model flies

7 July 2018

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Role of post-translational modifications in modulating the structure, function and toxicity of alpha-synuclein: implications for Parkinson's disease pathogenesis and therapies

7 July 2018

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Deamidation of alpha-synuclein

7 July 2018

1 reference

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Proteomics reveal a concerted upregulation of methionine metabolic pathway enzymes, and downregulation of carbonic anhydrase-III, in betaine supplemented ethanol-fed rats

7 July 2018

1 reference

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Beta-synuclein occurs in vivo in lipid-associated oligomers and forms hetero-oligomers with alpha-synuclein

7 July 2018

1 reference

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The therapeutical potential of alpha-synuclein antiaggregatory agents for dementia with Lewy bodies.

7 July 2018

1 reference

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Isoaspartate-containing amyloid precursor protein-derived peptides alter efficacy and specificity of potential beta-secretases

7 July 2018

1 reference

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Dynamics of alpha-synuclein aggregation and inhibition of pore-like oligomer development by beta-synuclein

7 July 2018

1 reference

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Accumulation of proteins bearing atypical isoaspartyl residues in livers of alcohol-fed rats is prevented by betaine administration: effects on protein-L-isoaspartyl methyltransferase activity

7 July 2018

1 reference

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Proteomic identification of novel substrates of a protein isoaspartyl methyltransferase repair enzyme

7 July 2018

1 reference

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Biological significance of isoaspartate and its repair system

7 July 2018

1 reference

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Beta-synuclein gene alterations in dementia with Lewy bodies

7 July 2018

1 reference

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The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

7 July 2018

1 reference

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alpha-Synuclein locus triplication causes Parkinson's disease

7 July 2018

1 reference

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Biophysical properties of the synucleins and their propensities to fibrillate: inhibition of alpha-synuclein assembly by beta- and gamma-synucleins

7 July 2018

1 reference

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7 July 2018

1 reference

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beta-Synuclein inhibits alpha-synuclein aggregation: a possible role as an anti-parkinsonian factor

7 July 2018

1 reference

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Alpha-synuclein and neurodegenerative diseases

7 July 2018

1 reference

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Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

7 July 2018

1 reference

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Deficiency in protein L-isoaspartyl methyltransferase results in a fatal progressive epilepsy

7 July 2018

1 reference

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Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

7 July 2018

1 reference

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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

7 July 2018

1 reference

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Deficiency of a protein-repair enzyme results in the accumulation of altered proteins, retardation of growth, and fatal seizures in mice.

7 July 2018

1 reference

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NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded

7 July 2018

1 reference

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Molecular aging of tubulin: accumulation of isoaspartyl sites in vitro and in vivo

7 July 2018

1 reference

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Accumulation of substrates for protein L-isoaspartyl methyltransferase in adenosine dialdehyde-treated PC12 cells

7 July 2018

1 reference

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Identification of two distinct synucleins from human brain

7 July 2018

1 reference

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Deamidation, isomerization, and racemization at asparaginyl and aspartyl residues in peptides. Succinimide-linked reactions that contribute to protein degradation

7 July 2018

1 reference

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Partial repair of deamidation-damaged calmodulin by protein carboxyl methyltransferase

7 July 2018

1 reference

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Protein carboxyl methyltransferase facilitates conversion of atypical L-isoaspartyl peptides to normal L-aspartyl peptides

7 July 2018

1 reference

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Conversion of isoaspartyl peptides to normal peptides: implications for the cellular repair of damaged proteins

7 July 2018

1 reference

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Diversity of methyl acceptor proteins in rat pheochromocytoma (PC12) cells revealed after treatment with adenosine dialdehyde.

7 July 2018

1 reference

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An antiaggregation gene therapy strategy for Lewy body disease utilizing beta-synuclein lentivirus in a transgenic model

7 July 2018

1 reference

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Structural integrity of histone H2B in vivo requires the activity of protein L-isoaspartate O-methyltransferase, a putative protein repair enzyme.

21 January 2018

1 reference

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Synapsin I is a major endogenous substrate for protein L-isoaspartyl methyltransferase in mammalian brain

21 January 2018

1 reference

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Formation, localization, and repair of L-isoaspartyl sites in histones H2A and H2B in nucleosomes from rat liver and chicken erythrocytes.

21 January 2018

1 reference

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Transgenic expression of the protein-L-isoaspartyl methyltransferase (PIMT) gene in the brain rescues mice from the fatal epilepsy of PIMT deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061442

Phenotypic analysis of seizure-prone mice lacking L-isoaspartate (D-aspartate) O-methyltransferase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061442

Aberrant synaptic transmission in the hippocampal CA3 region and cognitive deterioration in protein-repair enzyme-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061442

Activation of the PI3K/Akt signal transduction pathway and increased levels of insulin receptor in protein repair-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061442

Increased cell proliferation and granule cell number in the dentate gyrus of protein repair-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061442

Kinetic properties of bovine brain protein L-isoaspartyl methyltransferase determined using a synthetic isoaspartyl peptide substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061442

Spontaneous alterations in the covalent structure of synapsin I during in vitro aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061442

Limited accumulation of damaged proteins in l-isoaspartyl (D-aspartyl) O-methyltransferase-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061442

Analytical approaches to investigate protein-pesticide adducts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061442

The decrease of β-synuclein in cortical brain areas defines a molecular subgroup of dementia with Lewy bodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061442

Structure-dependent nonenzymatic deamidation of glutaminyl and asparaginyl pentapeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061442

Protein repair in the brain, proteomic analysis of endogenous substrates for protein L-isoaspartyl methyltransferase in mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061442

Isoaspartate formation at position 23 of amyloid beta peptide enhanced fibril formation and deposited onto senile plaques and vascular amyloids in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061442

Irreversible dimerization/tetramerization and post-translational modifications inhibit proteolytic degradation of A beta peptides of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061442

Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061442

Methylation status and neurodegenerative markers in Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061442

Repair of spontaneously deamidated HPr phosphocarrier protein catalyzed by the L-isoaspartate-(D-aspartate) O-methyltransferase

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632608

Folate status and age affect the accumulation of L-isoaspartyl residues in rat liver proteins

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23630590

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Beta-synuclein inhibits formation of alpha-synuclein protofibrils: a possible therapeutic strategy against Parkinson's disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23630590

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0061442

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23630590%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23630590%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23630590%20AND%20SRC:MED&resulttype=core&format=json