(Q34696470)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928797%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

title

Novel therapeutic approaches in multiple system atrophy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928797%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

main subject

multiple system atrophy

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928797%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Horacio Kaufmann

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928797%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1

Jose-Alberto Palma

1 reference

PubMed publication ID

4 August 2017

2

Horacio Kaufmann

1 reference

PubMed publication ID

24928797

4 August 2017

publication date

14 June 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928797%20AND%20SRC:MED&resulttype=core&format=json

Clinical Autonomic Research

20 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928797%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

volume

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928797%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928797%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

page(s)

37-45

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928797%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s10286-014-0249-7

20 March 2020

exact match

0 references

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Antibody-aided clearance of extracellular α-synuclein prevents cell-to-cell aggregate transmission

7 July 2018

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A randomized clinical trial of lithium in multiple system atrophy

7 July 2018

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Suppression of dynamin GTPase decreases α-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy

7 July 2018

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A randomized trial of mesenchymal stem cells in multiple system atrophy.

7 July 2018

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Oligodendroglia metabolically support axons and contribute to neurodegeneration.

7 July 2018

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G-protein-coupled receptor 30 mediates rapid neuroprotective effects of estrogen via depression of NR2B-containing NMDA receptors

7 July 2018

1 reference

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Systemic proteasome inhibition triggers neurodegeneration in a transgenic mouse model expressing human α-synuclein under oligodendrocyte promoter: implications for multiple system atrophy

7 July 2018

1 reference

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Evidence-based guideline: intravenous immunoglobulin in the treatment of neuromuscular disorders: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology

7 July 2018

1 reference

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Fluoxetine ameliorates behavioral and neuropathological deficits in a transgenic model mouse of α-synucleinopathy

7 July 2018

1 reference

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Role of α-synuclein penetration into the membrane in the mechanisms of oligomer pore formation

7 July 2018

1 reference

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Fluoxetine rescues impaired hippocampal neurogenesis in a transgenic A53T synuclein mouse model

7 July 2018

1 reference

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Fluoxetine protects neurons against microglial activation-mediated neurotoxicity

7 July 2018

1 reference

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Explaining ADAGIO: a critical review of the biological basis for the clinical effects of rasagiline

7 July 2018

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α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation

7 July 2018

1 reference

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Mesenchymal stem cells in a transgenic mouse model of multiple system atrophy: immunomodulation and neuroprotection

7 July 2018

1 reference

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Passive immunization reduces behavioral and neuropathological deficits in an alpha-synuclein transgenic model of Lewy body disease

7 July 2018

1 reference

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α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells

7 July 2018

1 reference

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Inhibiting α-synuclein oligomerization by stable cell-penetrating β-synuclein fragments recovers phenotype of Parkinson's disease model flies

7 July 2018

1 reference

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Presentation, diagnosis, and management of multiple system atrophy in Europe: final analysis of the European multiple system atrophy registry

7 July 2018

1 reference

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Neurodegeneration in a transgenic mouse model of multiple system atrophy is associated with altered expression of oligodendroglial-derived neurotrophic factors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Riluzole, neuroprotection and amyotrophic lateral sclerosis.

7 July 2018

1 reference

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Glutamate receptors, neurotoxicity and neurodegeneration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Entacapone and tolcapone, two catechol O-methyltransferase inhibitors, block fibril formation of alpha-synuclein and beta-amyloid and protect against amyloid-induced toxicity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Direct transfer of alpha-synuclein from neuron to astroglia causes inflammatory responses in synucleinopathies

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Minocycline 1-year therapy in multiple-system-atrophy: effect on clinical symptoms and [(11)C] (R)-PK11195 PET (MEMSA-trial).

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

A double-blind, delayed-start trial of rasagiline in Parkinson's disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Mitochondrial inhibitor 3-nitroproprionic acid enhances oxidative modification of alpha-synuclein in a transgenic mouse model of multiple system atrophy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Microtubule depolymerization suppresses alpha-synuclein accumulation in a mouse model of multiple system atrophy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Riluzole treatment, survival and diagnostic criteria in Parkinson plus disorders: the NNIPPS study

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

P2X7 receptors in oligodendrocytes: a novel target for neuroprotection

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Rifampicin reduces alpha-synuclein in a transgenic mouse model of multiple system atrophy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Glutamatergic signaling in the brain's white matter.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Assembly-dependent endocytosis and clearance of extracellular alpha-synuclein.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Origins and effects of extracellular alpha-synuclein: implications in Parkinson's disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Multiple system atrophy: alpha-synuclein and neuronal degeneration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

White matter NMDA receptors: an unexpected new therapeutic target?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

p25alpha relocalizes in oligodendroglia from myelin to cytoplasmic inclusions in multiple system atrophy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Microglial activation and its implications in the brain diseases.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Minocycline down-regulates MHC II expression in microglia and macrophages through inhibition of IRF-1 and protein kinase C (PKC)alpha/betaII

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Neurotransmitter-mediated calcium signalling in oligodendrocyte physiology and pathology

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Cytosolic catechols inhibit alpha-synuclein aggregation and facilitate the formation of intracellular soluble oligomeric intermediates.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Cellular pathology in multiple system atrophy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Mesenchymal stem cells as trophic mediators

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Peroxynitrite generated by inducible nitric oxide synthase and NADPH oxidase mediates microglial toxicity to oligodendrocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Oxidative stress in transgenic mice with oligodendroglial alpha-synuclein overexpression replicates the characteristic neuropathology of multiple system atrophy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

p25alpha Stimulates alpha-synuclein aggregation and is co-localized with aggregated alpha-synuclein in alpha-synucleinopathies

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Specific induction of neuronal cells from bone marrow stromal cells and application for autologous transplantation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

A strategy for designing inhibitors of alpha-synuclein aggregation and toxicity as a novel treatment for Parkinson's disease and related disorders

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Progression and prognosis in multiple system atrophy: an analysis of 230 Japanese patients

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Analysis of the expression level of alpha-synuclein mRNA using postmortem brain samples from pathologically confirmed cases of multiple system atrophy.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Glial cell line-derived neurotrophic factor-like immunoreactivity in the cerebella of normal subjects and patients with multiple system atrophy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble alpha-synuclein.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Identification of two distinct synucleins from human brain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Alpha-synuclein immunoreactivity in glial cytoplasmic inclusions in multiple system atrophy

7 July 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10286-014-0249-7

Brain alpha-synuclein accumulation in multiple system atrophy, Parkinson's disease and progressive supranuclear palsy: a comparative investigation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10286-014-0249-7

Absence of alpha-synuclein mRNA expression in normal and multiple system atrophy oligodendroglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10286-014-0249-7

Myeloperoxidase inhibition ameliorates multiple system atrophy-like degeneration in a transgenic mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10286-014-0249-7

Role of TPPP/p25 on α-synuclein-mediated oligodendroglial degeneration and the protective effect of SIRT2 inhibition in a cellular model of multiple system atrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10286-014-0249-7

The expression of tubulin polymerization promoting protein TPPP/p25alpha is developmentally regulated in cultured rat brain oligodendrocytes and affected by proteolytic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10286-014-0249-7

System xc- and glutamate transporter inhibition mediates microglial toxicity to oligodendrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10286-014-0249-7

Microglial activation parallels system degeneration in multiple system atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10286-014-0249-7

[11C](R)-PK11195 PET imaging of microglial activation in multiple system atrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10286-014-0249-7

Riluzole improves motor deficits and attenuates loss of striatal neurons in a sequential double lesion rat model of striatonigral degeneration (parkinson variant of multiple system atrophy).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10286-014-0249-7

Paroxetine treatment improves motor symptoms in patients with multiple system atrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10286-014-0249-7

Non-steroidal anti-inflammatory drugs have potent anti-fibrillogenic and fibril-destabilizing effects for alpha-synuclein fibrils in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10286-014-0249-7

Differential inhibition of α-synuclein oligomeric and fibrillar assembly in parkinson's disease model by cinnamon extract.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10286-014-0249-7

The efficacy of combined estrogen and buspirone treatment in olivopontocerebellar atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10286-014-0249-7

Rasagiline is neuroprotective in a transgenic model of multiple system atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10286-014-0249-7

Neuroprotective effect of human mesenchymal stem cells in an animal model of double toxin-induced multiple system atrophy parkinsonism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10286-014-0249-7

Autologous mesenchymal stem cell therapy delays the progression of neurological deficits in patients with multiple system atrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10286-014-0249-7

Specific antibodies to soluble alpha-synuclein conformations in intravenous immunoglobulin preparations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10286-014-0249-7

Neuropathology of fetal nigral grafts in patients with Parkinson's disease.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265580

Modulation of α-synuclein fibrillization by ring-fused 2-pyridones: Templation and inhibition involve oligomers with different structure

26 October 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10286-014-0249-7

Activation of Kainate Receptors Sensitizes Oligodendrocytes to Complement Attack

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10286-014-0249-7

Microglial activation mediates neurodegeneration related to oligodendroglial α-synucleinopathy: Implications for multiple system atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10286-014-0249-7

Are trials of intravascular infusions of autologous mesenchymal stem cells in patients with multiple system atrophy currently justified, and are they effective?

21 January 2018

1 reference

12 December 2020

Associations between multiple system atrophy and polymorphisms of SLC1A4, SQSTM1, and EIF4EBP1 genes

1 reference

12 December 2020

beta-Sheet-breaking peptides inhibit the fibrillation of human alpha-synuclein

1 reference

12 December 2020

Maintaining glottic opening in multiple system atrophy: efficacy of serotonergic therapy

1 reference

12 December 2020

Are trials of intravascular infusions of autologous mesenchymal stem cells in patients with multiple system atrophy currently justified, and are they effective?

1 reference

12 December 2020

Rapid ischemic cell death in immature oligodendrocytes: a fatal glutamate release feedback loop

1 reference

12 December 2020

1 reference

12 December 2020

1 reference

12 December 2020

Safety and tolerability of growth hormone therapy in multiple system atrophy: a double-blind, placebo-controlled study

1 reference

12 December 2020

Binding of neuronal α-synuclein to β-III tubulin and accumulation in a model of multiple system atrophy

1 reference

12 December 2020

10.1007/S10286-014-0249-7

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928797%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928797%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

PubMed publication ID

24928797

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928797%20AND%20SRC:MED&resulttype=core&format=json