(Q34707994)

4 August 2017

1 reference

title

Chemotherapy of varicella-zoster virus by a novel class of highly specific anti-VZV bicyclic pyrimidine nucleosides (English)

1 reference

4 August 2017

1 reference

1

J Balzarini

1 reference

4 August 2017

C McGuigan

2

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PubMed ID

12084470

4 August 2017

language of work or name

English

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publication date

1 July 2002

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Biochimica et Biophysica Acta

4 August 2017

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4 August 2017

1587

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4 August 2017

2-3

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4 August 2017

287-295

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Biochemical aspects of the selective antiherpes activity of nucleoside analogues

4 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900091-1

7 January 2021

(E)-5-(2-Bromovinyl)-2'-deoxyuridine: a potent and selective anti-herpes agent

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900091-1

7 January 2021

Characterization of pyrimidine deoxyribonucleoside kinase (thymidine kinase) and thymidylate kinase as a multifunctional enzyme in cells transformed by herpes simplex virus type 1 and in cells infected with mutant strains of herpes simplex virus

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900091-1

7 January 2021

Inhibition of thymidylate synthetase by 5-alkynyl-2'-deoxyuridylates

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900091-1

7 January 2021

5-Substituted 2'-deoxyuridines: correlation between inhibition of tumor cell growth and inhibition of thymidine kinase and thymidylate synthetase

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900091-1

7 January 2021

Crystal structures of the thymidine kinase from herpes simplex virus type-1 in complex with deoxythymidine and ganciclovir

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900091-1

7 January 2021

The three-dimensional structure of thymidine kinase from herpes simplex virus type 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900091-1

7 January 2021

The structures of thymidine kinase from herpes simplex virus type 1 in complex with substrates and a substrate analogue

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900091-1

7 January 2021

Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligands

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900091-1

7 January 2021

Structure to 1.9 A resolution of a complex with herpes simplex virus type-1 thymidine kinase of a novel, non-substrate inhibitor: X-ray crystallographic comparison with binding of aciclovir

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900091-1

7 January 2021

Evolution of herpesvirus thymidine kinases from cellular deoxycytidine kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900091-1

7 January 2021

Potent and selective inhibition of varicella-zoster virus (VZV) by nucleoside analogues with an unusual bicyclic base

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900091-1

7 January 2021

Highly potent and selective inhibition of varicella-zoster virus by bicyclic furopyrimidine nucleosides bearing an aryl side chain

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900091-1

7 January 2021

Fluorescent bicyclic furo pyrimidine deoxynucleoside analogs as potent and selective inhibitors of VZV and potential future drugs for the treatment of chickenpox and shingles

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900091-1

7 January 2021

Furano pyrimidines as novel potent and selective anti-VZV agents

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900091-1

7 January 2021

Bicyclic nucleoside inhibitors of Varicella-Zoster Virus (VZV): the effect of terminal unsaturation in the side chain

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900091-1

7 January 2021

Bicyclic nucleoside inhibitors of Varicella-Zoster Virus (VZV): the effect of a terminal halogen substitution in the side-chain.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900091-1

7 January 2021

Anti-varicella-zoster virus bicyclic nucleosides: replacement of furo by pyrro base reduces antiviral potency

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900091-1

7 January 2021

Bicyclic anti-VZV nucleosides: Thieno analogues retain full antiviral activity

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900091-1

7 January 2021

Antiherpesviral activity and inhibitory action on cell growth of 5-alkenyl derivatives of 1-beta D-arabinofuranosyluracil

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900091-1

7 January 2021

(E)-5-(2-bromovinyl)uridine requires phosphorylation by the herpes simplex virus (type 1)-induced thymidine kinase to express its antiviral activity

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900091-1

7 January 2021

Synthesis and anti-varicella-zoster virus activity of some novel bicyclic nucleoside inhibitors: effect of enhanced aqueous solubility

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900091-1

7 January 2021

Specific recognition of the bicyclic pyrimidine nucleoside analogs, a new class of highly potent and selective inhibitors of varicella-zoster virus (VZV), by the VZV-encoded thymidine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900091-1

7 January 2021

Phosphorolysis of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and other 5-substituted-2'-deoxyuridines by purified human thymidine phosphorylase and intact blood platelets

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900091-1

7 January 2021

Lack of susceptibility of bicyclic nucleoside analogs, highly potent inhibitors of varicella-zoster virus, to the catabolic action of thymidine phosphorylase and dihydropyrimidine dehydrogenase

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900091-1

7 January 2021

10.1016/S0925-4439(02)00091-1

Identifiers

DOI

1 reference

4 August 2017

1 reference

PubMed ID

12084470