(Q34718192)

4 August 2017

title

Cardiomyocyte lipids impair β-adrenergic receptor function via PKC activation (English)

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4 August 2017

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Anastasios Lymperopoulos

3

object named as

Anastasios Lymperopoulos

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author name string

Konstantinos Drosatos

1

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4 August 2017

Kalyani G Bharadwaj

2

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4 August 2017

Shota Ikeda

4

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4 August 2017

Raffay Khan

5

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4 August 2017

Yunying Hu

6

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4 August 2017

Rajiv Agarwal

7

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4 August 2017

Shuiqing Yu

8

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4 August 2017

Hongfeng Jiang

9

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4 August 2017

Susan F Steinberg

10

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4 August 2017

William S Blaner

11

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4 August 2017

Walter J Koch

12

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4 August 2017

Ira J Goldberg

13

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4 August 2017

publication date

7 December 2010

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American Journal of Physiology - Endocrinology and Metabolism

4 August 2017

published in

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4 August 2017

volume

300

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4 August 2017

issue

3

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4 August 2017

page(s)

E489-99

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PPARγ-induced cardiolipotoxicity in mice is ameliorated by PPARα deficiency despite increases in fatty acid oxidation.

4 August 2017

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Activation of PKC-delta and SHP-1 by hyperglycemia causes vascular cell apoptosis and diabetic retinopathy

7 July 2018

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7 July 2018

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7 July 2018

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DGAT1 expression increases heart triglyceride content but ameliorates lipotoxicity

7 July 2018

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Protein kinase C{alpha}, but not PKC{beta} or PKC{gamma}, regulates contractility and heart failure susceptibility: implications for ruboxistaurin as a novel therapeutic approach

7 July 2018

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7 July 2018

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Ceramide is a cardiotoxin in lipotoxic cardiomyopathy

7 July 2018

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7 July 2018

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Cardiomyocyte expression of PPARgamma leads to cardiac dysfunction in mice

7 July 2018

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Muscle-specific knockout of PKC-lambda impairs glucose transport and induces metabolic and diabetic syndromes

7 July 2018

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7 July 2018

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Effects of insulin replacements, inhibitors of angiotensin, and PKCbeta's actions to normalize cardiac gene expression and fuel metabolism in diabetic rats

7 July 2018

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Pharmacological- and gene therapy-based inhibition of protein kinase Calpha/beta enhances cardiac contractility and attenuates heart failure

7 July 2018

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A critical role for eukaryotic elongation factor 1A-1 in lipotoxic cell death

7 July 2018

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Novel cell lines derived from adult human ventricular cardiomyocytes

7 July 2018

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A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress

7 July 2018

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PKC-theta knockout mice are protected from fat-induced insulin resistance

7 July 2018

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PKC-alpha regulates cardiac contractility and propensity toward heart failure

7 July 2018

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7 July 2018

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Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes

7 July 2018

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Triglyceride accumulation protects against fatty acid-induced lipotoxicity

7 July 2018

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Lipoprotein lipase (LpL) on the surface of cardiomyocytes increases lipid uptake and produces a cardiomyopathy

7 July 2018

1 reference

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Regulation of G protein-coupled receptor kinases and arrestins during receptor desensitization

7 July 2018

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Adaptation and maladaptation of the heart in diabetes: Part I: general concepts

7 July 2018

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7 July 2018

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Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin

7 July 2018

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Altered beta-adrenergic receptor gene regulation and signaling in chronic heart failure

7 July 2018

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7 July 2018

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A novel mouse model of lipotoxic cardiomyopathy

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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The role of sequestration in G protein-coupled receptor resensitization. Regulation of beta2-adrenergic receptor dephosphorylation by vesicular acidification

7 July 2018

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Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor

7 July 2018

1 reference

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Dynamin and beta-arrestin reveal distinct mechanisms for G protein-coupled receptor internalization

7 July 2018

1 reference

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Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalization

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064003

Ceramide synthesis enhances transport of GPI-anchored proteins to the Golgi apparatus in yeast.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064003

Use of a PCR-based method to characterize protein kinase C isoform expression in cardiac cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064003

Adrenergic control of the force-frequency relation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064003

7 July 2018

1 reference

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sn-1,2-Dioctanoylglycerol. A cell-permeable diacylglycerol that mimics phorbol diester action on the epidermal growth factor receptor and mitogenesis.

7 July 2018

1 reference

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Beta-adrenergic receptor-coupled adenylate cyclase. Biochemical mechanisms of regulation

7 July 2018

1 reference

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Molecular species analysis of 1,2-diglycerides stimulated by alpha-thrombin in cultured fibroblasts

7 July 2018

1 reference

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Beta-adrenergic pathways in nonfailing and failing human ventricular myocardium.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064003

Acute elevation of plasma lipids does not affect ATP synthesis in human skeletal muscle

7 July 2018

1 reference

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Selective and transient activation of protein kinase C alpha by fumonisin B1, a ceramide synthase inhibitor mycotoxin, in cultured porcine renal cells

21 January 2018

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Role of specific protein kinase C isoforms in modulation of beta1- and beta2-adrenergic receptors.

21 January 2018

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Characterization of cardiomyocyte excitation-contraction coupling in the FVB/N-C57BL/6 intercrossed "chocolate" brown mice

21 January 2018

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Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic beta-cell turnover and function

21 January 2018

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Differential effects of saturated and unsaturated fatty acid diets on cardiomyocyte apoptosis, adipose distribution, and serum leptin

21 January 2018

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Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart.

21 January 2018

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Anesthetic inhibition in ischemic and nonischemic murine heart: comparison with conscious echocardiographic approach

21 January 2018

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Fatty acyl CoA-mediated inhibition of endoplasmic reticulum assembly

21 January 2018

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Detection of silent myocardial ischemia in asymptomatic diabetic subjects: the DIAD study

21 January 2018

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Effect of post-myocardial infarction exercise training on the renin-angiotensin-aldosterone system and cardiac function

21 January 2018

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Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle

21 January 2018

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Palmitate-mediated Alterations in the Fatty Acid Metabolism of Rat Neonatal Cardiac Myocytes

21 January 2018

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Validated Comprehensive Analytical Method for Quantification of Coenzyme A Activated Compounds in Biological Tissues by Online Solid-Phase Extraction LC/MS/MS

21 January 2018

1 reference

12 December 2020

Inhibition of protein kinase C-beta by ruboxistaurin preserves cardiac function and reduces extracellular matrix production in diabetic cardiomyopathy

1 reference

12 December 2020

Decreased Catecholamine Sensitivity and β-Adrenergic-Receptor Density in Failing Human Hearts

1 reference

12 December 2020

A metabolic role for mitochondria in palmitate-induced cardiac myocyte apoptosis

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12 December 2020

Quantitative determination of ceramide using diglyceride kinase

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12 December 2020

Beta-adrenergic receptor signaling pathways mediating cell survival in cardiomyocytes: a role for PKC epsilon inhibition?

1 reference

12 December 2020

Suppression of murine cardiac allograft arteriopathy by long-term blockade of CD40-CD154 interactions

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12 December 2020

Isolation and culture of adult mouse cardiac myocytes

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12 December 2020

Adrenal GRK2 upregulation mediates sympathetic overdrive in heart failure

1 reference

12 December 2020

10.1152/AJPENDO.00569.2010

Identifiers

DOI

1 reference

4 August 2017

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4 August 2017

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