(Q34737733)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23704950%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Relaxin prevents cardiac fibroblast-myofibroblast transition via notch-1-mediated inhibition of TGF-β/Smad3 signaling (English)

1 reference

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1 March 2020

3

1 reference

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1 March 2020

8

Daniele Bani

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23704950%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

author name string

Chiara Sassoli

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23704950%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Flaminia Chellini

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23704950%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Alessia Tani

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23704950%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Silvia Nistri

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23704950%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Daniele Nosi

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23704950%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Sandra Zecchi-Orlandini

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23704950%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Lucia Formigli

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23704950%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

language of work or name

English

0 references

publication date

21 May 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23704950%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23704950%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23704950%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

issue

5

1 reference

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1 March 2020

page(s)

e63896

1 reference

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Creative Commons Attribution 4.0 International

1 March 2020

copyright license

start time

21 May 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3660557/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial

7 July 2018

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7 July 2018

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7 July 2018

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Relaxin signals through a RXFP1-pERK-nNOS-NO-cGMP-dependent pathway to up-regulate matrix metalloproteinases: the additional involvement of iNOS.

7 July 2018

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Relaxin induces matrix-metalloproteinases-9 and -13 via RXFP1: induction of MMP-9 involves the PI3K, ERK, Akt and PKC-ζ pathways

7 July 2018

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Bone marrow mesenchymal stromal cells stimulate skeletal myoblast proliferation through the paracrine release of VEGF

7 July 2018

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Relaxin as a cardiovascular drug: a promise kept.

7 July 2018

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The role of Adams in Notch signaling

7 July 2018

1 reference

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Notch receptor-ligand binding and activation: insights from molecular studies

7 July 2018

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The regulation of fibrosis in airway remodeling in asthma

7 July 2018

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Alternative origins of stroma in normal organs and disease

7 July 2018

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The role of ADAM-mediated shedding in vascular biology.

7 July 2018

1 reference

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Relaxin regulates myofibroblast contractility and protects against lung fibrosis

7 July 2018

1 reference

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Relaxin regulates MMP expression and promotes satellite cell mobilization during muscle healing in both young and aged mice.

7 July 2018

1 reference

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Prevention of bleomycin-induced pulmonary fibrosis by a novel antifibrotic peptide with relaxin-like activity

7 July 2018

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The role of SnoN in transforming growth factor beta1-induced expression of metalloprotease-disintegrin ADAM12.

7 July 2018

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Cardiovascular effects of relaxin: from basic science to clinical therapy

7 July 2018

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Clinical profile of relaxin, a possible new drug for human use.

7 July 2018

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Investigations into the inhibitory effects of relaxin on renal myofibroblast differentiation

7 July 2018

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Notch1 signaling in FIZZ1 induction of myofibroblast differentiation

7 July 2018

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Relaxin for the treatment of patients with acute heart failure (Pre-RELAX-AHF): a multicentre, randomised, placebo-controlled, parallel-group, dose-finding phase IIb study.

7 July 2018

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7 July 2018

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Relaxin inhibits renal myofibroblast differentiation via RXFP1, the nitric oxide pathway, and Smad2

7 July 2018

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The effects of relaxin on extracellular matrix remodeling in health and fibrotic disease

7 July 2018

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7 July 2018

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7 July 2018

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Crossing paths with Notch in the hyper-network

7 July 2018

1 reference

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7 July 2018

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Relaxin: antifibrotic properties and effects in models of disease

7 July 2018

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7 July 2018

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Inducible nitric oxide synthase up-regulates Notch-1 in mouse cholangiocytes: implications for carcinogenesis

7 July 2018

1 reference

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7 July 2018

1 reference

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Cross-talk between the Notch and TGF-beta signaling pathways mediated by interaction of the Notch intracellular domain with Smad3

7 July 2018

1 reference

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7 July 2018

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7 July 2018

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7 July 2018

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Increased myocardial collagen and ventricular diastolic dysfunction in relaxin deficient mice: a gender-specific phenotype.

7 July 2018

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Relaxin-1-deficient mice develop an age-related progression of renal fibrosis

21 January 2018

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Relaxin modulates cardiac fibroblast proliferation, differentiation, and collagen production and reverses cardiac fibrosis in vivo

21 January 2018

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Regulation of myofibroblast transdifferentiation by DNA methylation and MeCP2: implications for wound healing and fibrogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0063896

Pancreatic regeneration in chronic pancreatitis requires activation of the notch signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0063896

HDAC-mediated control of ERK- and PI3K-dependent TGF-β-induced extracellular matrix-regulating genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0063896

Skeletal myoblasts overexpressing relaxin improve differentiation and communication of primary murine cardiomyocyte cell cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0063896

Relaxin promotes growth and maturation of mouse neonatal cardiomyocytes in vitro: clues for cardiac regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0063896

Increased expression of integrin alpha(v)beta3 contributes to the establishment of autocrine TGF-beta signaling in scleroderma fibroblasts

21 January 2018

1 reference

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Alterations in mRNA and protein levels of metalloproteinases-2, -9, and -14 and tissue inhibitor of metalloproteinase-2 responses to traumatic skeletal muscle injury.

21 January 2018

1 reference

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Notch signaling may negatively regulate neonatal rat cardiac fibroblast-myofibroblast transformation

21 January 2018

1 reference

12 December 2020

Relaxin deficiency in mice is associated with an age-related progression of pulmonary fibrosis

1 reference

12 December 2020

Relaxin remodels fibrotic healing following myocardial infarction

1 reference

12 December 2020

Transforming growth factor-beta (TGF- 1) down-regulates Notch3 in fibroblasts to promote smooth muscle gene expression

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12 December 2020

The effect of relaxin treatment on skeletal muscle injuries

1 reference

12 December 2020

Mesenchymal stromal cells affect cardiomyocyte growth through juxtacrine Notch-1/Jagged-1 signaling and paracrine mechanisms: clues for cardiac regeneration

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12 December 2020

10.1371/JOURNAL.PONE.0063896

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23704950%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23704950%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23704950%20AND%20SRC:MED&resulttype=core&format=json