(Q34752562)

4 August 2017

The charged linker of the molecular chaperone Hsp90 modulates domain contacts and biological function (English)

1 reference

4 August 2017

0 references

Thorsten Hugel

8

0 references

Klaus Richter

object named as

Klaus Richter

5

0 references

author name string

Markus Jahn

1

1 reference

4 August 2017

Alexandra Rehn

2

1 reference

4 August 2017

Benjamin Pelz

3

1 reference

4 August 2017

Björn Hellenkamp

4

1 reference

4 August 2017

Matthias Rief

6

1 reference

4 August 2017

Johannes Buchner

7

1 reference

4 August 2017

language of work or name

English

0 references

publication date

2 December 2014

1 reference

Proceedings of the National Academy of Sciences of the United States of America

4 August 2017

1 reference

4 August 2017

111

1 reference

4 August 2017

50

1 reference

4 August 2017

17881-17886

1 reference

Designed Hsp90 heterodimers reveal an asymmetric ATPase-driven mechanism in vivo.

4 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273377

Integration of the accelerator Aha1 in the Hsp90 co-chaperone cycle

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273377

Limitations of constant-force-feedback experiments

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273377

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273377

Chaperoning the chaperone: a role for the co-chaperone Cpr7 in modulating Hsp90 function in Saccharomyces cerevisiae.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273377

Charged linker sequence modulates eukaryotic heat shock protein 90 (Hsp90) chaperone activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273377

Cross-monomer substrate contacts reposition the Hsp90 N-terminal domain and prime the chaperone activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273377

The complex folding network of single calmodulin molecules

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273377

The Hsp90 chaperone machinery: conformational dynamics and regulation by co-chaperones

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273377

Substrate binding drives large-scale conformational changes in the Hsp90 molecular chaperone

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273377

Mixed Hsp90-cochaperone complexes are important for the progression of the reaction cycle

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273377

The charged linker region is an important regulator of Hsp90 function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273377

Direct observation of hierarchical folding in single riboswitch aptamers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273377

Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273377

Direct observation of the three-state folding of a single protein molecule

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273377

Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273377

Structural and functional analysis of the middle segment of hsp90: implications for ATP hydrolysis and client protein and cochaperone interactions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273377

Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273377

Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273377

Data registration and selective single-molecule analysis using multi-parameter fluorescence detection

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273377

In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273377

ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273377

Two eukaryote-specific regions of Hsp82 are dispensable for its viability and signal transduction functions in yeast

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273377

Probing the interaction between two single molecules: fluorescence resonance energy transfer between a single donor and a single acceptor.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273377

The large conformational changes of Hsp90 are only weakly coupled to ATP hydrolysis

7 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1414073111

Dissection of the ATP-induced conformational cycle of the molecular chaperone Hsp90.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1414073111

Co-chaperone regulation of conformational switching in the Hsp90 ATPase cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1414073111

The Co-chaperone Sba1 connects the ATPase reaction of Hsp90 to the progression of the chaperone cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1414073111

Hsp90 charged-linker truncation reverses the functional consequences of weakened hydrophobic contacts in the N domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1414073111

Asymmetric Activation of the Hsp90 Dimer by Its Cochaperone Aha1

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25468961

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Hidden Markov Analysis of Trajectories in Single-Molecule Experiments and the Effects of Missed Events

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25468961

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1414073111

1 reference

4 August 2017

0 references

1 reference

4 August 2017

1 reference