(Q34771074)

4 August 2017

title

Janus kinase 2 regulates Bcr-Abl signaling in chronic myeloid leukemia (English)

1 reference

4 August 2017

main subject

chronic myeloid leukemia

0 references

1 reference

A Samanta

1

1 reference

4 August 2017

B Perazzona

2

1 reference

4 August 2017

S Chakraborty

3

1 reference

4 August 2017

X Sun

4

1 reference

4 August 2017

H Modi

5

1 reference

4 August 2017

R Bhatia

6

1 reference

4 August 2017

W Priebe

7

1 reference

4 August 2017

R Arlinghaus

8

1 reference

4 August 2017

publication date

24 December 2010

1 reference

4 August 2017

1 reference

4 August 2017

volume

25

1 reference

4 August 2017

issue

3

1 reference

4 August 2017

page(s)

463-472

1 reference

https://scigraph.springernature.com/pub.10.1038/leu.2010.287

4 August 2017

exact match

0 references

cites work

Destabilization of Bcr-Abl/Jak2 Network by a Jak2/Abl Kinase Inhibitor ON044580 Overcomes Drug Resistance in Blast Crisis Chronic Myelogenous Leukemia (CML)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072513

The chronic myeloid leukemia stem cell

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072513

Jak2 inhibition deactivates Lyn kinase through the SET-PP2A-SHP1 pathway, causing apoptosis in drug-resistant cells from chronic myelogenous leukemia patients

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072513

Chronic myeloid leukemia stem cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072513

BCR-ABL-transformed GMP as myeloid leukemic stem cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072513

The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072513

BCR-ABL oncogenic transformation of NIH 3T3 fibroblasts requires the IL-3 receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072513

Characterization of cancer stem cells in chronic myeloid leukaemia.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072513

TG101209, a small molecule JAK2-selective kinase inhibitor potently inhibits myeloproliferative disorder-associated JAK2V617F and MPLW515L/K mutations

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072513

Janus kinase 2: a critical target in chronic myelogenous leukemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072513

Simultaneous activation of JAK1 and JAK2 confers IL-3 independent growth on Ba/F3 pro-B cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072513

Autophosphorylation of JAK2 on tyrosines 221 and 570 regulates its activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072513

Imatinib mesylate resistance through BCR-ABL independence in chronic myelogenous leukemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072513

JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072513

The Src family kinase Hck couples BCR/ABL to STAT5 activation in myeloid leukemia cells.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072513

Jak2 is involved in c-Myc induction by Bcr-Abl

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072513

Critical role for Gab2 in transformation by BCR/ABL

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072513

Involvement of Jak2 tyrosine phosphorylation in Bcr-Abl transformation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072513

Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072513

The NH(2)-terminal coiled-coil domain and tyrosine 177 play important roles in induction of a myeloproliferative disease in mice by Bcr-Abl

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072513

Dominant negative mutants implicate STAT5 in myeloid cell proliferation and neutrophil differentiation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072513

Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072513

P210 Bcr-Abl interacts with the interleukin 3 receptor beta(c) subunit and constitutively induces its tyrosine phosphorylation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072513

Inhibition of Bcr serine kinase by tyrosine phosphorylation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072513

Bcr-Abl oncoproteins bind directly to activators of the Ras signalling pathway

7 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072513

7 July 2018

https://api.crossref.org/works/10.1038%2FLEU.2010.287

7 January 2021

inferred from DOI database lookup

The BCR gene encodes a novel serine/threonine kinase activity within a single exon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072513

BCR-tyrosine 177 plays an essential role in Ras and Akt activation and in human hematopoietic progenitor transformation in chronic myelogenous leukemia

7 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.287

Real-time quantitative PCR analysis can be used as a primary screen to identify patients with CML treated with imatinib who have BCR-ABL kinase domain mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.287

BCR-ABL independence and LYN kinase overexpression in chronic myelogenous leukemia cells selected for resistance to STI571.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.287

The CML stem cell: evolution of the progenitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.287

Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow

21 January 2018

1 reference

12 December 2020

Real-time quantitation of bcr-abl transcripts in haematological malignancies

1 reference

12 December 2020

Requirement of two specific tyrosine residues for the catalytic activity of Bcr serine/threonine kinase

1 reference

12 December 2020

BCR-ABL activates STAT3 via JAK and MEK pathways in human cells

1 reference

12 December 2020

Identifiers

DOI

10.1038/LEU.2010.287

1 reference

Dimensions Publication ID

4 August 2017

1016272292

0 references

Fatcat ID

release_xsgi2po3lfdzjjgywhw3s7yctu

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/xsgi2po3lfdzjjgywhw3s7yctu

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3072513

1 reference

4 August 2017

1 reference