(Q34776057)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23776569%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

title

Functional assessment of population and tumor-associated APE1 protein variants (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23776569%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

6

1 reference

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3 March 2020

author name string

Jennifer L Illuzzi

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23776569%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Nicole A Harris

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23776569%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Brittney A Manvilla

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23776569%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Daemyung Kim

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23776569%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Mengxia Li

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23776569%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

David M Wilson

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23776569%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

language of work or name

English

0 references

publication date

11 June 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23776569%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23776569%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23776569%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23776569%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

page(s)

e65922

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23776569%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons CC0 License

3 March 2020

copyright license

start time

11 June 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

0 references

describes a project that uses

ImageQuant

object named as

ImageQuant

2 references

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3679070/fullTextXML

inferred from PubMed Central ID database lookup

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

cites work

A germline polymorphism of DNA polymerase beta induces genomic instability and cellular transformation

1 reference

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Evolution of the cancer genome

7 July 2018

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Base excision repair: contribution to tumorigenesis and target in anticancer treatment paradigms

7 July 2018

1 reference

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APE1/Ref-1 role in redox signaling: translational applications of targeting the redox function of the DNA repair/redox protein APE1/Ref-1.

7 July 2018

1 reference

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Haploinsufficiency in mouse models of DNA repair deficiency: modifiers of penetrance

7 July 2018

1 reference

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XRCC1 haploinsufficiency in mice has little effect on aging, but adversely modifies exposure-dependent susceptibility

7 July 2018

1 reference

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Human cancers express mutator phenotypes: origin, consequences and targeting

7 July 2018

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Variation in base excision repair capacity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679070

Variant base excision repair proteins: contributors to genomic instability

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679070

Posttranslational modification of mammalian AP endonuclease (APE1).

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679070

Folate deficiency provides protection against colon carcinogenesis in DNA polymerase beta haploinsufficient mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679070

Functional capacity of XRCC1 protein variants identified in DNA repair-deficient Chinese hamster ovary cell lines and the human population

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679070

Human AP endonuclease 1 (APE1): from mechanistic insights to druggable target in cancer.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679070

Identification of Apurinic/apyrimidinic endonuclease 1 (APE1) as the endoribonuclease that cleaves c-myc mRNA

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679070

DNA repair in mammalian cells: Base excision repair: the long and short of it.

7 July 2018

1 reference

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Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679070

DNA-damage repair; the good, the bad, and the ugly

7 July 2018

1 reference

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Base damage and single-strand break repair: mechanisms and functional significance of short- and long-patch repair subpathways

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679070

Genetic polymorphisms in the base excision repair pathway and cancer risk: a HuGE review

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679070

Expression of DNA polymerase {beta} cancer-associated variants in mouse cells results in cellular transformation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679070

AP endonuclease-independent DNA base excision repair in human cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679070

Properties of and substrate determinants for the exonuclease activity of human apurinic endonuclease Ape1.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679070

A quantitative model of human DNA base excision repair. I. Mechanistic insights

7 July 2018

1 reference

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The major human abasic endonuclease: formation, consequences and repair of abasic lesions in DNA.

7 July 2018

1 reference

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Functional characterization of Ape1 variants identified in the human population

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679070

Neonatal lethality with abnormal neurogenesis in mice deficient in DNA polymerase beta

7 July 2018

1 reference

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Reliable identification of large numbers of candidate SNPs from public EST data

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679070

Elements in abasic site recognition by the major human and Escherichia coli apurinic/apyrimidinic endonucleases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679070

Abasic site binding by the human apurinic endonuclease, Ape, and determination of the DNA contact sites

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679070

The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679070

Requirement of mammalian DNA polymerase-beta in base-excision repair.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679070

Instability and decay of the primary structure of DNA

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679070

Repair of oxidative damage to DNA: enzymology and biology

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679070

Site-directed mutagenesis of the human DNA repair enzyme HAP1: identification of residues important for AP endonuclease and RNase H activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679070

Incision Activity of Human Apurinic Endonuclease (Ape) at Abasic Site Analogs in DNA

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679070

The redox and DNA-repair activities of Ref-1 are encoded by nonoverlapping domains

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679070

Mutagenesis by apurinic/apyrimidinic sites

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679070

Unfolding free energy changes determined by the linear extrapolation method. 1. Unfolding of phenylmethanesulfonyl alpha-chymotrypsin using different denaturants

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679070

A mouse DNA repair enzyme (APEX nuclease) having exonuclease and apurinic/apyrimidinic endonuclease activities: purification and characterization

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679070

Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679070

Haploinsufficiency in DNA polymerase beta increases cancer risk with age and alters mortality rate.

7 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065922

Many amino acid substitution variants identified in DNA repair genes during human population screenings are predicted to impact protein function

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065922

Functional sites of interaction between release factor RF1 and the ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065922

Requirement for the Xrcc1 DNA base excision repair gene during early mouse development

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065922

Major oxidative products of cytosine are substrates for the nucleotide incision repair pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065922

Defining folding and unfolding reactions of apocytochrome b5 using equilibrium and kinetic fluorescence measurements

21 January 2018

1 reference

12 December 2020

Passing the baton in base excision repair

1 reference

12 December 2020

Mapping the protein-DNA interface and the metal-binding site of the major human apurinic/apyrimidinic endonuclease

1 reference

12 December 2020

Common polymorphisms and somatic mutations in human base excision repair genes in ovarian and endometrial cancers

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0065922

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23776569%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23776569%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

PubMed publication ID

23776569

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23776569%20AND%20SRC:MED&resulttype=core&format=json