(Q34820024)

4 August 2017

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title

Regulation of gene expression by WT1 in development and tumorigenesis (English)

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4 August 2017

1

Leif W Ellisen

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4 August 2017

1 August 2002

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International Journal of Hematology

4 August 2017

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4 August 2017

76

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4 August 2017

2

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4 August 2017

110-116

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https://scigraph.springernature.com/pub.10.1007/bf02982572

4 August 2017

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cites work

Sequence and structural requirements for high-affinity DNA binding by the WT1 gene product

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FBF02982572

The Wilms' tumor suppressor gene (wt1) product regulates Dax-1 gene expression during gonadal differentiation

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FBF02982572

Repression of the insulin-like growth factor II gene by the Wilms tumor suppressor WT1

21 January 2018

1 reference

12 December 2020

Wilms' tumor 1 and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression

1 reference

12 December 2020

The evolution of WT1 sequence and expression pattern in the vertebrates

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12 December 2020

Two N-terminal self-association domains are required for the dominant negative transcriptional activity of WT1 Denys-Drash mutant proteins

1 reference

12 December 2020

Subnuclear localization of WT1 in splicing or transcription factor domains is regulated by alternative splicing

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12 December 2020

Differentially spliced exon 5 of the Wilms' tumor gene WT1 modifies gene function

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12 December 2020

Overlapping RNA and DNA binding domains of the wt1 tumor suppressor gene product

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12 December 2020

Transcriptional repression of the insulin-like growth factor I receptor (IGF-I-R) gene by the tumor suppressor WT1 involves binding to sequences both upstream and downstream of the IGF-I-R gene transcription start site

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12 December 2020

WT-1 is required for early kidney development

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12 December 2020

Constitutional mutations in the WT1 gene in patients with Denys-Drash syndrome

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12 December 2020

Presence of WT1, the Wilm's tumor suppressor gene product, in nuclear poly(A)(+) ribonucleoprotein

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12 December 2020

WT1 interacts with the splicing factor U2AF65 in an isoform-dependent manner and can be incorporated into spliceosomes

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12 December 2020

WT1 suppresses synthesis of the epidermal growth factor receptor and induces apoptosis

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12 December 2020

Molecular basis for modulation of biological function by alternate splicing of the Wilms' tumor suppressor protein

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12 December 2020

The human sex-determining gene SRY is a direct target of WT1.

1 reference

12 December 2020

WT1 modulates apoptosis by transcriptionally upregulating the bcl-2 proto-oncogene

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12 December 2020

The genetics of Wilms' tumor

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12 December 2020

The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis

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12 December 2020

Transcriptional repression mediated by the WT1 Wilms tumor gene product

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12 December 2020

Transcriptional activation of the syndecan-1 promoter by the Wilms' tumor protein WT1.

1 reference

12 December 2020

A non-AUG translational initiation event generates novel WT1 isoforms

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12 December 2020

The Wilms tumor suppressor WT1 encodes a transcriptional activator of amphiregulin

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12 December 2020

An RNA recognition motif in Wilms' tumour protein (WT1) revealed by structural modelling.

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12 December 2020

Induction of p21 by the Wilms' tumor suppressor gene WT1

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12 December 2020

Analysis of WT1 target gene expression in stably transfected cell lines

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12 December 2020

A second transcriptionally active DNA-binding site for the Wilms tumor gene product, WT1

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12 December 2020

WT1 mutations associated with incomplete Denys-Drash syndrome define a domain predicted to behave in a dominant-negative fashion

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12 December 2020

WT1 regulates the expression of the major glomerular podocyte membrane protein Podocalyxin

1 reference

12 December 2020

The Wilms' tumor gene product WT1 activates or suppresses transcription through separate functional domains

1 reference

12 December 2020

The Wilms tumor suppressor WT1 directs stage-specific quiescence and differentiation of human hematopoietic progenitor cells

1 reference

12 December 2020

A mammal-specific exon of WT1 is not required for development or fertility

1 reference

12 December 2020

Truncated WT1 mutants alter the subnuclear localization of the wild-type protein

1 reference

12 December 2020

The Wilms' tumor gene product (WT1) modulates the response to 1,25-dihydroxyvitamin D3 by induction of the vitamin D receptor

1 reference

12 December 2020

Identification of nuclear localization signals within the zinc fingers of the WT1 tumor suppressor gene product

1 reference

12 December 2020

Products of alternatively spliced transcripts of the Wilms' tumor suppressor gene, wt1, have altered DNA binding specificity and regulate transcription in different ways.

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12 December 2020

E-cadherin is a WT1 target gene

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12 December 2020

Two splice variants of the Wilms' tumor 1 gene have distinct functions during sex determination and nephron formation

1 reference

12 December 2020

Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome

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12 December 2020

RNA binding by the Wilms tumor suppressor zinc finger proteins.

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12 December 2020

WT1-mediated transcriptional activation is inhibited by dominant negative mutant proteins.

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12 December 2020

Donor splice-site mutations in WT1 are responsible for Frasier syndrome

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12 December 2020

Internal translation initiation generates novel WT1 protein isoforms with distinct biological properties

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12 December 2020

A functional interaction with CBP contributes to transcriptional activation by the Wilms tumor suppressor WT1.

1 reference

12 December 2020

Binding of the Wilms' tumor locus zinc finger protein to the EGR-1 consensus sequence

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12 December 2020

The transcriptional effect of WT1 is modulated by choice of expression vector

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12 December 2020

Physical and functional interaction between WT1 and p53 proteins

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12 December 2020

A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization

1 reference

12 December 2020

Zinc finger point mutations within the WT1 gene in Wilms tumor patients

1 reference

12 December 2020

Human platelet-derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1

1 reference

12 December 2020

Alternative splicing and genomic structure of the Wilms tumor gene WT1

1 reference

12 December 2020

Tumor-associated WT1 missense mutants indicate that transcriptional activation by WT1 is critical for growth control

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF02982572

1 reference

PubMed ID

12215008

Dimensions Publication ID

4 August 2017

0 references

1 reference

PubMed ID

12215008