(Q34841459)

4 August 2017

title

Negative self-regulation of TLR9 signaling by its N-terminal proteolytic cleavage product (English)

1 reference

4 August 2017

0 references

1 reference

5

Hidde L Ploegh

1 reference

4 August 2017

Sungwook Lee

1

1 reference

4 August 2017

Dongju Kang

2

1 reference

4 August 2017

Eun A Ra

3

1 reference

4 August 2017

Taeyun A Lee

4

1 reference

4 August 2017

Boyoun Park

6

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4 August 2017

language of work or name

English

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publication date

3 September 2014

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4 August 2017

published in

Journal of Immunology

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4 August 2017

volume

193

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4 August 2017

issue

7

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4 August 2017

page(s)

3726-3735

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Crystal structure of the C-terminal domain of mouse TLR9

4 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285150

Cell-specific TLR9 trafficking in primary APCs of transgenic TLR9-GFP mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285150

Accessory molecules for Toll-like receptors and their function

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285150

DNA binding to proteolytically activated TLR9 is sequence-independent and enhanced by DNA curvature

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285150

Negative regulation of signaling by a soluble form of toll-like receptor 9.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285150

Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285150

Soluble TLR2 reduces inflammation without compromising bacterial clearance by disrupting TLR2 triggering

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285150

Identification of an N-terminal recognition site in TLR9 that contributes to CpG-DNA-mediated receptor activation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285150

Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285150

The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285150

UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285150

Ligand-induced conformational changes allosterically activate Toll-like receptor 9.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285150

The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285150

Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285150

Toll-like receptors in the pathogenesis of human disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285150

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285150

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285150

TLR9 signals after translocating from the ER to CpG DNA in the lysosome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285150

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285150

Role of the NF-kappaB pathway in the pathogenesis of human disease states

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285150

Innate immune recognition

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285150

NF-kappaB: a key role in inflammatory diseases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285150

A Toll-like receptor recognizes bacterial DNA

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285150

An essential role for the N-terminal fragment of Toll-like receptor 9 in DNA sensing.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285150

Critical role for asparagine endopeptidase in endocytic Toll-like receptor signaling in dendritic cells

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285150

Soluble TLR2 is present in human amniotic fluid and modulates the intraamniotic inflammatory response to infection.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285150

Soluble forms of Toll-like receptor 4 are present in human saliva and modulate tumour necrosis factor-alpha secretion by macrophage-like cells.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285150

Asparagine endopeptidase is not essential for class II MHC antigen presentation but is required for processing of cathepsin L in mice.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285150

26 October 2018

Identifiers

DOI

10.4049/JIMMUNOL.1400210

1 reference

release_hg6em4asgfa43okuhgax7fbkge

4 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/hg6em4asgfa43okuhgax7fbkge

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

4285150

1 reference

4 August 2017

1 reference