(Q34907640)

English

In vivo administration of a JAK3 inhibitor to chronically siv infected rhesus macaques leads to NK cell depletion associated with transient modest increase in viral loads

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Europe PubMed Central

PubMed publication ID

5 August 2017

In vivo administration of a JAK3 inhibitor to chronically siv infected rhesus macaques leads to NK cell depletion associated with transient modest increase in viral loads (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

1 reference

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Aftab A. Ansari

7

object named as

Aftab A Ansari

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Europe PubMed Central

PubMed publication ID

5 August 2017

Kovit Pattanapanyasat

4

object named as

Kovit Pattanapanyasat

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Francois Villinger

6

object named as

Francois Villinger

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

2

object named as

Ann E Mayne

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

author name string

Yoshiaki Takahashi

1

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Ladawan Khowawisetsut

3

1 reference

Europe PubMed Central

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5 August 2017

Dawn Little

5

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Europe PubMed Central

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5 August 2017

language of work or name

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publication date

26 July 2013

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Europe PubMed Central

PubMed publication ID

5 August 2017

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Europe PubMed Central

PubMed publication ID

5 August 2017

8

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Europe PubMed Central

PubMed publication ID

5 August 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

e70992

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

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Creative Commons Attribution 4.0 International

26 July 2013

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April 2022 Public Data File from Crossref

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0 references

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1 reference

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Inhibitors of JAK2 and JAK3: an update on the patent literature 2010 - 2012.

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Cutting edge: antibody-dependent memory-like NK cells distinguished by FcRγ deficiency

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Changes in Natural Killer cell activation and function during primary HIV-1 Infection

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New views of the human NK cell immunological synapse: recent advances enabled by super- and high-resolution imaging techniques

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The depletion of NK cells prevents T cell exhaustion to efficiently control disseminating virus infection

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3-Amido pyrrolopyrazine JAK kinase inhibitors: development of a JAK3 vs JAK1 selective inhibitor and evaluation in cellular and in vivo models

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Role of transmitted Gag CTL polymorphisms in defining replicative capacity and early HIV-1 pathogenesis

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Loss of a tyrosine-dependent trafficking motif in the simian immunodeficiency virus envelope cytoplasmic tail spares mucosal CD4 cells but does not prevent disease progression

1 reference

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Cytokine activation induces human memory-like NK cells

1 reference

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NK cells regulate CD8+ T cell priming and dendritic cell migration during influenza A infection by IFN-γ and perforin-dependent mechanisms.

1 reference

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The chemoattractant chemerin suppresses melanoma by recruiting natural killer cell antitumor defenses.

1 reference

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IL-17-producing innate lymphoid cells are restricted to mucosal tissues and are depleted in SIV-infected macaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

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Differential effects of denileukin diftitox IL-2 immunotoxin on NK and regulatory T cells in nonhuman primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

JAK and STAT signaling molecules in immunoregulation and immune-mediated disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

The JAK-STAT pathway at twenty

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

The Jak/STAT pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

Biology and significance of the JAK/STAT signalling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

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Defining early human NK cell developmental stages in primary and secondary lymphoid tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

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NK cells--from bench to clinic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

miR-150 regulates the development of NK and iNKT cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

Natural killer cells act as rheostats modulating antiviral T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

NK cell development, homeostasis and function: parallels with CD8⁺ T cells

1 reference

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Incorporation of innate immune effector mechanisms in the formulation of a vaccine against HIV-1.

1 reference

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Development of thymic NK cells from double negative 1 thymocyte precursors

1 reference

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8 July 2018

Gut inflammation and indoleamine deoxygenase inhibit IL-17 production and promote cytotoxic potential in NKp44+ mucosal NK cells during SIV infection

1 reference

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Unifying concepts of MHC-dependent natural killer cell education

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

Regulation of NK cell repertoire and function in the liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

Modulation of innate and adaptive immune responses by tofacitinib (CP-690,550).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

Innate or adaptive immunity? The example of natural killer cells

1 reference

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8 July 2018

Blocking of α4β7 gut-homing integrin during acute infection leads to decreased plasma and gastrointestinal tissue viral loads in simian immunodeficiency virus-infected rhesus macaques

1 reference

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Innate Immune Natural Killer Cells and Their Role in HIV and SIV Infection

1 reference

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8 July 2018

Memory-like responses of natural killer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

Targeting early infection to prevent HIV-1 mucosal transmission.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

NK cells influence both innate and adaptive immune responses after mucosal immunization with antigen and mucosal adjuvant.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

Regulation of human NK-cell cytokine and chemokine production by target cell recognition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

The safety and efficacy of a JAK inhibitor in patients with active rheumatoid arthritis: Results of a double-blind, placebo-controlled phase IIa trial of three dosage levels of CP-690,550 versus placebo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

CD56bright natural killer (NK) cells: an important NK cell subset.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

Natural killer cell tolerance licensing and other mechanisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

A case for innate immune effector mechanisms as contributors to disease resistance in SIV-infected sooty mangabeys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

IL-15 trans-presentation promotes human NK cell development and differentiation in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

Human natural killer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

Noncytotoxic functions of NK cells: direct pathogen restriction and assistance to adaptive immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

In vivo natural killer cell depletion during primary simian immunodeficiency virus infection in rhesus monkeys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

The trafficking of natural killer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

No evidence for consistent virus-specific immunity in simian immunodeficiency virus-exposed, uninfected rhesus monkeys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

Evidence for discrete stages of human natural killer cell differentiation in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

JAK3 inhibition, a viable new modality of immunosuppression for solid organ transplants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

Human natural killer cell deficiencies and susceptibility to infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

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Titration of an SIVmac251 stock by vaginal inoculation of Indian and Chinese origin rhesus macaques: transmission efficiency, viral loads, and antibody responses

1 reference

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Synergistic effects of in vivo depletion of Ly-49A and Ly-49G2 natural killer cell subsets in the rejection of H2(b) bone marrow cell allografts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

In vivo natural killer cell activities revealed by natural killer cell-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

Simian immunodeficiency virus disease course is predicted by the extent of virus replication during primary infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

The role of natural killer cells in host-parasite interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

Age-associated decline in natural killer (NK) activity reflects primarily a defect in function of NK cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

Biology of natural killer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724739

8 July 2018

In HIV-1 pathogenesis the die is cast during primary infection

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0070992

21 January 2018

Human fetal lymphoid tissue-inducer cells are interleukin 17-producing precursors to RORC+ CD127+ natural killer-like cells

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0070992

21 January 2018

Notch activation induces the generation of functional NK cells from human cord blood CD34-positive cells devoid of IL-15.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0070992

21 January 2018

Immunoregulatory natural killer cells suppress autoimmunity by down-regulating antigen-specific CD8+ T cells in mice

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0070992

21 January 2018

Natural killer cell memory.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0070992

21 January 2018

Licensing of natural killer cells by host major histocompatibility complex class I molecules

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0070992

21 January 2018

Critical role for the chemokine receptor CXCR6 in NK cell-mediated antigen-specific memory of haptens and viruses.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0070992

21 January 2018

Innate immune responses involving natural killer and natural killer T cells promote liver regeneration after partial hepatectomy in mice.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0070992

21 January 2018

Severe herpesvirus infections in an adolescent without natural killer cells

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0070992

21 January 2018

Use of an anti-CD16 antibody for in vivo depletion of natural killer cells in rhesus macaques.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0070992

21 January 2018

Effects of JAK3 inhibition with CP-690,550 on immune cell populations and their functions in nonhuman primate recipients of kidney allografts

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0070992

21 January 2018

The JAK3 inhibitor CP-690550 selectively reduces NK and CD8+ cell numbers in cynomolgus monkey blood following chronic oral dosing

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0070992

21 January 2018

Quantitative analysis of the immunosuppressant CP-690,550 in whole blood by column-switching high-performance liquid chromatography and mass spectrometry detection

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0070992

21 January 2018

Combined use of the JAK3 inhibitor CP-690,550 with mycophenolate mofetil to prevent kidney allograft rejection in nonhuman primates

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0070992

21 January 2018

Phase 1 dose-escalation study of CP-690 550 in stable renal allograft recipients: preliminary findings of safety, tolerability, effects on lymphocyte subsets and pharmacokinetics

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0070992

21 January 2018

Phenotypically and functionally distinct subsets contribute to the expansion of CD56-/CD16+ natural killer cells in HIV infection.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0070992

21 January 2018

NK cell-depleting anti-asialo GM1 antibody exhibits a lethal off-target effect on basophils in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/23923040

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sooty mangabeys and rhesus macaques exhibit significant divergent natural killer cell responses during both acute and chronic phases of SIV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/23923040

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulatory NK cells suppress antigen-specific T cell responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/23923040

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The JAM Test and its daughter P-JAM: simple tests of DNA fragmentation to measure cell death and stasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23923040

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) or adalimumab monotherapy versus placebo in patients with active rheumatoid arthritis with an inadequate response to disease-modifying antirheumatic drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/23923040

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo regulation of experimental autoimmune encephalomyelitis by NK cells: alteration of primary adaptive responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/23923040

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0070992

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

2013PLoSO...870992T

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

ResearchGate publication ID

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