(Q34916871)

5 August 2017

title

Clostridium difficile 027/BI/NAP1 encodes a hypertoxic and antigenically variable form of TcdB. (English)

1 reference

5 August 2017

main subject

Clostridium difficile

0 references

3

Judith A James

1 reference

5 August 2017

Jordi M Lanis

1

1 reference

5 August 2017

Latisha D Heinlen

series ordinal

2

1 reference

5 August 2017

Jimmy D Ballard

series ordinal

4

1 reference

5 August 2017

publication date

1 August 2013

1 reference

5 August 2017

1 reference

5 August 2017

volume

9

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5 August 2017

issue

8

1 reference

5 August 2017

page(s)

e1003523

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Creative Commons Attribution 4.0 International

5 August 2017

copyright license

start time

1 August 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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8 July 2018

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8 July 2018

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8 July 2018

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Human monoclonal antibodies directed against toxins A and B prevent Clostridium difficile-induced mortality in hamsters

8 July 2018

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8 July 2018

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An epidemic, toxin gene-variant strain of Clostridium difficile

8 July 2018

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A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731247

Liver abscess caused by Clostridium difficile

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731247

Safety and immunogenicity of increasing doses of a Clostridium difficile toxoid vaccine administered to healthy adults

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731247

Asymptomatic carriage of Clostridium difficile and serum levels of IgG antibody against toxin A.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731247

Serum antitoxin antibodies mediate systemic and mucosal protection from Clostridium difficile disease in hamsters.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731247

Antibodies to recombinant Clostridium difficile toxins A and B are an effective treatment and prevent relapse of C. difficile-associated disease in a hamster model of infection.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731247

Localization of the glucosyltransferase activity of Clostridium difficile toxin B to the N-terminal part of the holotoxin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731247

Diagnosis and treatment of Clostridium difficile colitis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731247

Closing in on the toxic domain through analysis of a variant Clostridium difficile cytotoxin B.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731247

Comparison of two toxins produced by Clostridium difficile

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731247

Effects of the two toxins of Clostridium difficile in antibiotic-associated cecitis in hamsters.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731247

Primary culture of rat cerebral microvascular endothelial cells. Isolation, growth, and characterization.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731247

Immunization of adult hamsters against Clostridium difficile-associated ileocecitis and transfer of protection to infant hamsters

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731247

Purification of Clostridium difficile toxin A by affinity chromatography on immobilized thyroglobulin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731247

Nosocomial acquisition of Clostridium difficile infection

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731247

Characterization of toxins A and B of Clostridium difficile with monoclonal antibodies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731247

Clostridium difficile toxin A carries a C-terminal repetitive structure homologous to the carbohydrate binding region of streptococcal glycosyltransferases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731247

Risk factors for the development of Clostridium difficile-associated diarrhea during a hospital outbreak

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731247

A family of clostridial and streptococcal ligand-binding proteins with conserved C-terminal repeat sequences

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731247

Comparative sequence analysis of the Clostridium difficile toxins A and B.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731247

Antibiotic-associated diarrhea

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731247

Characterization of a toxin A-negative, toxin B-positive strain of Clostridium difficile

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731247

Evidence for a modular structure of the homologous repetitive C-terminal carbohydrate-binding sites of Clostridium difficile toxins and Streptococcus mutans glucosyltransferases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731247

Role of Clostridium difficile in antibiotic-associated pseudomembranous colitis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731247

Increasing risk of relapse after treatment of Clostridium difficile colitis in Quebec, Canada

8 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003523

A large outbreak of Clostridium difficile-associated disease with an unexpected proportion of deaths and colectomies at a teaching hospital following increased fluoroquinolone use.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003523

Changing epidemiology of Clostridium difficile infection following the introduction of a national ribotyping-based surveillance scheme in England

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003523

gyrA mutations in fluoroquinolone-resistant Clostridium difficile PCR-027.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003523

High-level resistance to moxifloxacin and gatifloxacin associated with a novel mutation in gyrB in toxin-A-negative, toxin-B-positive Clostridium difficile

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003523

Auto-catalytic cleavage of Clostridium difficile toxins A and B depends on cysteine protease activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003523

The toxigenic element of Clostridium difficile strain VPI 10463.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003523

Clostridium difficile colitis causing toxic megacolon, severe sepsis and multiple organ dysfunction syndrome

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003523

Anti-inflammatory effects of tocopherol metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003523

Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003523

Formaldehyde-mediated aggregation of protein antigens: comparison of untreated and formalinized model antigens

21 January 2018

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12 December 2020

Lysosomal involvement in cellular intoxication with Clostridium difficile toxin B

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12 December 2020

Peptide autoantigenicity of the small nuclear ribonucleoprotein C

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12 December 2020

Antigenicity of amino-acid sequences from Clostridium difficile toxin B

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12 December 2020

Clostridium difficile colitis associated with chronic renal failure

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12 December 2020

A portrait of the geographic dissemination of the Clostridium difficile North American pulsed-field type 1 strain and the epidemiology of C. difficile-associated disease in Québec

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12 December 2020

Global epidemiology of Clostridium difficile infection in 2010

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12 December 2020

10.1371/JOURNAL.PPAT.1003523

Identifiers

DOI

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5 August 2017

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5 August 2017

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