(Q34938739)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24869773%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

title

Lysine methylation is an endogenous post-translational modification of tau protein in human brain and a modulator of aggregation propensity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24869773%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24869773%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

David J Clark

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24869773%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

author name string

Kristen E Funk

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24869773%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Kelsey N Schafer

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24869773%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Grace L Cooper

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24869773%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Zhongping Liao

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24869773%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Austin J Yang

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24869773%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Jeff Kuret

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24869773%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

language of work or name

English

0 references

publication date

1 August 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24869773%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24869773%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

volume

462

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24869773%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

page(s)

77-88

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24869773%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24869773%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

19 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4292886/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Acetylation of the KXGS motifs in tau is a critical determinant in modulation of tau aggregation and clearance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Tau pathology and neurodegeneration

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Histone lysine methylation dynamics: establishment, regulation, and biological impact

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Abnormal hyperphosphorylation of tau: sites, regulation, and molecular mechanism of neurofibrillary degeneration

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Tau isoform composition influences rate and extent of filament formation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Dual modification of Alzheimer's disease PHF-tau protein by lysine methylation and ubiquitylation: a mass spectrometry approach

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Phosphorylation of microtubule-associated protein tau by AMPK-related kinases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Implicating calpain in tau-mediated toxicity in vivo

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

8 July 2018

The many faces of tau

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

The acetylation of tau inhibits its function and promotes pathological tau aggregation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Post-translational modifications of tau protein: implications for Alzheimer's disease.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Prmt5 is essential for early mouse development and acts in the cytoplasm to maintain ES cell pluripotency

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Uncovering the human methyltransferasome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Acetylation of tau inhibits its degradation and contributes to tauopathy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Tau phosphorylation: the therapeutic challenge for neurodegenerative disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Pathogenic missense MAPT mutations differentially modulate tau aggregation propensity at nucleation and extension steps

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Modification of amino groups

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Nucleation-dependent tau filament formation: the importance of dimerization and an estimation of elementary rate constants

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Tau aggregation and toxicity in a cell culture model of tauopathy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Dysbindin structural homologue CK1BP is an isoform-selective binding partner of human casein kinase-1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

NMDA receptor mediates tau-induced neurotoxicity by calpain and ERK/MAPK activation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

The generation of a 17 kDa neurotoxic fragment: an alternative mechanism by which tau mediates beta-amyloid-induced neurodegeneration.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

A static laser light scattering assay for surfactant-induced tau fibrillization

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Active caspase-6 and caspase-6-cleaved tau in neuropil threads, neuritic plaques, and neurofibrillary tangles of Alzheimer's disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

CHIP-Hsc70 Complex Ubiquitinates Phosphorylated Tau and Enhances Cell Survival

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Regulation of chromatin structure by site-specific histone H3 methyltransferases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif ((306)VQIVYK(311)) forming beta structure

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Tau cleavage and dephosphorylation in cerebellar granule neurons undergoing apoptosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Functional interactions between the proline-rich and repeat regions of tau enhance microtubule binding and assembly

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Domains of tau protein, differential phosphorylation, and dynamic instability of microtubules

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Interaction of tau with the neural plasma membrane mediated by tau's amino-terminal projection domain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Identification of a novel microtubule binding and assembly domain in the developmentally regulated inter-repeat region of tau.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Sense and antisense transfection analysis of tau function: tau influences net microtubule assembly, neurite outgrowth and neuritic stability.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: implications for the pathogenesis and treatment of Alzheimer disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Molecular characterization of the minimal protease resistant tau unit of the Alzheimer's disease paired helical filament

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Tau protein function in living cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Effects of the neuronal phosphoprotein synapsin I on actin polymerization. II. Analytical interpretation of kinetic curves

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Phosphate analysis and dephosphorylation of modified tau associated with paired helical filaments

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Tubulin requires tau for growth onto microtubule initiating sites

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

A protein factor essential for microtubule assembly

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Tau conformational changes correspond to impairments of episodic memory in mild cognitive impairment and Alzheimer's disease.

8 July 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140372

Novel phosphorylation sites in tau from Alzheimer brain support a role for casein kinase 1 in disease pathogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140372

Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140372

Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140372

Site-specific pseudophosphorylation modulates the rate of tau filament dissociation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140372

Alzheimer disease-specific conformation of hyperphosphorylated paired helical filament-Tau is polyubiquitinated through Lys-48, Lys-11, and Lys-6 ubiquitin conjugation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140372

Caspase-9 activation and caspase cleavage of tau in the Alzheimer's disease brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140372

Cyanohydridoborate anion as a selective reducing agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140372

Reductive alkylation of amino groups in proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140372

Glycogen synthase kinase 3beta phosphorylates tau at both primed and unprimed sites. Differential impact on microtubule binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140372

Triggers of full-length tau aggregation: a role for partially folded intermediates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140372

Analysis of protein aggregation kinetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140372

Detection of phosphorylated Ser262 in fetal tau, adult tau, and paired helical filament tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140372

Polycomb group protein ezh2 controls actin polymerization and cell signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140372

Electron microscopy as a quantitative method for investigating tau fibrillization

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140372

Reversible paired helical filament-like phosphorylation of tau is an adaptive process associated with neuronal plasticity in hibernating animals.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Dynamics of linear protein polymer disassembly.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292886

Microtubule assembly nucleated by isolated centrosomes

26 October 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140372

Characterization of two VQIXXK motifs for tau fibrillization in vitro

21 January 2018

1 reference

12 December 2020

Ubiquitin is conjugated with amino-terminally processed tau in paired helical filaments

1 reference

12 December 2020

Tau in paired helical filaments is functionally distinct from fetal tau: assembly incompetence of paired helical filament-tau

1 reference

12 December 2020

Domains of tau protein and interactions with microtubules

1 reference

12 December 2020

Labeling of proteins by reductive methylation using sodium cyanoborohydride

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ20140372

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24869773%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24869773%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference