(Q34956813)

5 August 2017

The Gordian Knot of dysbiosis, obesity and NAFLD. (English)

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5 August 2017

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Wajahat Z Mehal

1

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PubMed ID

23958600

5 August 2017

language of work or name

English

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publication date

20 August 2013

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Nature Reviews Gastroenterology & Hepatology

5 August 2017

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5 August 2017

10

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5 August 2017

637-644

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5 August 2017

11

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https://scigraph.springernature.com/pub.10.1038/nrgastro.2013.146

5 August 2017

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cites work

The human intestinal microbiome: a new frontier of human biology

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Functional interactions between the gut microbiota and host metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Interactions between the microbiota and the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Prions: reassessment of the germ theory of disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

A human gut microbial gene catalogue established by metagenomic sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Metagenomic analysis of the human distal gut microbiome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Microbial culturomics: paradigm shift in the human gut microbiome study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Diversity of the human intestinal microbial flora

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Genomic approaches to studying the human microbiota

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Diversity of human intestinal helminthiasis in Lao PDR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Diversity, stability and resilience of the human gut microbiota

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

The core gut microbiome, energy balance and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Getting to the core of the gut microbiome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Beyond the Venn diagram: the hunt for a core microbiome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

The importance of the development of the intestinal microbiota in infancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Linking long-term dietary patterns with gut microbial enterotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Role of obesity and lipotoxicity in the development of nonalcoholic steatohepatitis: pathophysiology and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Microbial ecology: human gut microbes associated with obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Human gut microbiota in obesity and after gastric bypass

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

An obesity-associated gut microbiome with increased capacity for energy harvest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

High-fat diet determines the composition of the murine gut microbiome independently of obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Composition and energy harvesting capacity of the gut microbiota: relationship to diet, obesity and time in mouse models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

An opportunistic pathogen isolated from the gut of an obese human causes obesity in germfree mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Transfer of intestinal microbiota from lean donors increases insulin sensitivity in individuals with metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

The gut microbiota, obesity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

The fermentable fibre inulin increases postprandial serum short-chain fatty acids and reduces free-fatty acids and ghrelin in healthy subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

The gut microbiota as an environmental factor that regulates fat storage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

The gut microbiota modulates host energy and lipid metabolism in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Energy-balance studies reveal associations between gut microbes, caloric load, and nutrient absorption in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Activation of G protein-coupled receptor 43 in adipocytes leads to inhibition of lipolysis and suppression of plasma free fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Toll-like receptors (TLR2 and TLR4) recognize polysaccharides of Pseudallescheria boydii cell wall.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Gut microbiota is a key modulator of insulin resistance in TLR 2 knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Encapsulated Bifidobacteria reduced bacterial translocation in rats following hemorrhagic shock and resuscitation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Increased intestinal permeability in obese mice: new evidence in the pathogenesis of nonalcoholic steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

A marker of endotoxemia is associated with obesity and related metabolic disorders in apparently healthy Chinese

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Involvement of tissue bacteria in the onset of diabetes in humans: evidence for a concept

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Metabolic endotoxemia initiates obesity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

The liver as a lymphoid organ

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Sterile inflammation in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Adipose tissue inflammation and liver pathology in human obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Gut microbiota and non-alcoholic fatty liver disease: new insights

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Role of phosphatidylcholine biosynthesis in the regulation of lipoprotein homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Association between composition of the human gastrointestinal microbiome and development of fatty liver with choline deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Innate immune signalling at the intestinal epithelium in homeostasis and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Inflammasomes and their roles in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

The inflammasome NLRs in immunity, inflammation, and associated diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Integrative inflammasome activity in the regulation of intestinal mucosal immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Inflammasomes: far beyond inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Modulation of non-alcoholic steatohepatitis by pattern recognition receptors in mice: the role of toll-like receptors 2 and 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Non-alcoholic fatty liver disease as a risk factor for hepatocellular carcinoma: mechanisms and implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Non-alcoholic fatty liver disease progresses to hepatocellular carcinoma in the absence of apparent cirrhosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Promotion of hepatocellular carcinoma by the intestinal microbiota and TLR4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Role of the microenvironment in the pathogenesis and treatment of hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Liver repercussions of defective gut surveillance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Probiotics in the treatment of the liver diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Gut microbiota and probiotics in chronic liver diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Gut microbiota, intestinal permeability, obesity-induced inflammation, and liver injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Probiotics improve high fat diet-induced hepatic steatosis and insulin resistance by increasing hepatic NKT cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

VSL#3 probiotic treatment attenuates fibrosis without changes in steatohepatitis in a diet-induced nonalcoholic steatohepatitis model in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Protective effects of Lactobacillus paracasei F19 in a rat model of oxidative and metabolic hepatic injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

A Toll-like receptor recognizes bacterial DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

The potential role of prebiotic fibre for treatment and management of non-alcoholic fatty liver disease and associated obesity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Review article: prebiotics in the gastrointestinal tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Microbiota and SCFA in lean and overweight healthy subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Prebiotics and lipid metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Dietary inulin alleviates hepatic steatosis and xenobiotics-induced liver injury in rats fed a high-fat and high-sucrose diet: association with the suppression of hepatic cytochrome P450 and hepatocyte nuclear factor 4alpha expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Comparison of enzymatically synthesized inulin, resistant maltodextrin and clofibrate effects on biomarkers of metabolic disease in rats fed a high-fat and high-sucrose (cafeteria) diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Physiological effects of dietary fructans extracted from Agave tequilana Gto. and Dasylirion spp.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Oligofructose promotes satiety in rats fed a high-fat diet: involvement of glucagon-like Peptide-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Effects of oligofructose on glucose and lipid metabolism in patients with nonalcoholic steatohepatitis: results of a pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Loss of insulin resistance after Roux-en-Y gastric bypass surgery: a time course study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Prospective study of the long-term effects of bariatric surgery on liver injury in patients without advanced disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Movers and shakers: influence of bacteriophages in shaping the mammalian gut microbiota

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

TLR9 and the NLRP3 inflammasome link acinar cell death with inflammation in acute pancreatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

A novel small-molecule enantiomeric analogue of traditional (-)-morphinans has specific TLR9 antagonist properties and reduces sterile inflammation-induced organ damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Gut microbiota: Diet promotes dysbiosis and colitis in susceptible hosts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Inulin-type fructans with prebiotic properties counteract GPR43 overexpression and PPARγ-related adipogenesis in the white adipose tissue of high-fat diet-fed mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Energy intake is associated with endotoxemia in apparently healthy men.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

The role of bifidobacteria in gut barrier function after thermal injury in rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Hepatic injury associated with small bowel bacterial overgrowth in rats is prevented by metronidazole and tetracycline

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

The gut-liver axis: a busy two-way street

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Effects of Lactobacillus rhamnosus Strain GG in Pediatric Obesity-related Liver Disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Involvement of lipogenesis in the lower VLDL secretion induced by oligofructose in rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Plasma lipids and fatty acid synthase activity are regulated by short-chain fructo-oligosaccharides in sucrose-fed insulin-resistant rats.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Dietary fructans, but not cellulose, decrease triglyceride accumulation in the liver of obese Zucker fa/fa rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

High propionic acid fermentations and mineral accumulation in the cecum of rats adapted to different levels of inulin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Short-chain fatty acids and human colonic function: roles of resistant starch and nonstarch polysaccharides

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2013.146

Effect of a probiotic on liver aminotransferases in nonalcoholic fatty liver disease patients: a double blind randomized clinical trial

31 March 2020

1 reference

12 December 2020

Bacteriophage Administration Reduces the Concentration of Listeria monocytogenes in the Gastrointestinal Tract and Its Translocation to Spleen and Liver in Experimentally Infected Mice

1 reference

12 December 2020

Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome.

1 reference

12 December 2020

Formation of methylamines from ingested choline and lecithin.

1 reference

12 December 2020

10.1038/NRGASTRO.2013.146

Identifiers

DOI

1 reference

5 August 2017

1 reference

PubMed ID

23958600