(Q34981216)

5 August 2017

title

Trade-off in the effects of the apolipoprotein E polymorphism on the ages at onset of CVD and cancer influences human lifespan (English)

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5 August 2017

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Alexander M Kulminski

1

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5 August 2017

Irina Culminskaya

2

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5 August 2017

Svetlana V Ukraintseva

3

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5 August 2017

Konstantin G Arbeev

4

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5 August 2017

Liubov Arbeeva

5

1 reference

5 August 2017

Deqing Wu

6

1 reference

5 August 2017

Igor Akushevich

7

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5 August 2017

Kenneth C Land

8

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5 August 2017

Anatoli I Yashin

9

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5 August 2017

publication date

7 April 2011

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5 August 2017

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5 August 2017

volume

10

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5 August 2017

issue

3

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5 August 2017

page(s)

533-541

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Genome-wide association study (GWAS)-identified disease risk alleles do not compromise human longevity

5 August 2017

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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FOXO3A genotype is strongly associated with human longevity

8 July 2018

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8 July 2018

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Signaling networks in aging

8 July 2018

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Impact of apoE genotype on oxidative stress, inflammation and disease risk

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094490

Shifting paradigm of association studies: value of rare single-nucleotide polymorphisms

8 July 2018

1 reference

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Pursuing the longevity dividend: scientific goals for an aging world

8 July 2018

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Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study

8 July 2018

1 reference

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The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports

8 July 2018

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Genetic determinants of human health span and life span: progress and new opportunities

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094490

The human disease network

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094490

Modalities of gene action predicted by the classical evolutionary biological theory of aging

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094490

Systemic inflammation, infection, ApoE alleles, and Alzheimer disease: a position paper

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094490

Role of apolipoprotein E4 in protecting children against early childhood diarrhea outcomes and implications for later development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094490

Genes, ageing and longevity in humans: problems, advantages and perspectives.

8 July 2018

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8 July 2018

The adversities of aging

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Association between apolipoprotein E polymorphisms and age-related macular degeneration: A HuGE review and meta-analysis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094490

The quest for genetic determinants of human longevity: challenges and insights

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094490

An evolutionary framework for common diseases: the ancestral-susceptibility model

8 July 2018

1 reference

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The plasticity of aging: insights from long-lived mutants

8 July 2018

1 reference

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Genetics of longevity and aging

8 July 2018

1 reference

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APOE4 protects the cognitive development in children with heavy diarrhea burdens in Northeast Brazil

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094490

Impact of APOE in mild cognitive impairment

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094490

Apolipoprotein E and the risk of breast cancer in African-American and non-Hispanic white women. A review

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094490

Unique lipoprotein phenotype and genotype associated with exceptional longevity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094490

Apolipoproteins and aging: emerging mechanisms

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094490

Apolipoprotein E polymorphism and cardiovascular disease: a HuGE review

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094490

Apolipoprotein E genotype, serum lipids, and colorectal adenomas in Japanese men.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094490

Apolipoprotein E variation at the sequence haplotype level: implications for the origin and maintenance of a major human polymorphism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094490

APOE alleles and lipophylic pathogens

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094490

Genetic association of apolipoprotein E with age-related macular degeneration

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094490

The epsilon4 allele of the apolipoprotein E gene as a potential protective factor for exudative age-related macular degeneration.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094490

Is the development of adenoma and carcinoma in proximal colon related to apolipoprotein E phenotype?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094490

Evolution of senescence: Alzheimer's disease and evolution

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094490

Apolipoprotein E: a potent inhibitor of endothelial and tumor cell proliferation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094490

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094490

Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094490

The framingham offspring study. Design and preliminary data

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094490

Age-Related Macular Degeneration

8 July 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00689.X

A prospective study of high-density lipoprotein cholesterol, cholesteryl ester transfer protein gene variants, and healthy aging in very old Japanese-american men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00689.X

Apolipoprotein E genotype and cardiovascular disease in the Framingham Heart Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00689.X

Apolipoprotein E, dementia, and human longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00689.X

Cortical morphology in children and adolescents with different apolipoprotein E gene polymorphisms: an observational study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00689.X

Associations between apoE genotype and colon and rectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00689.X

Apolipoprotein E-epsilon 4 protects against severe liver disease caused by hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00689.X

Common disorders are quantitative traits

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00689.X

The Third Generation Cohort of the National Heart, Lung, and Blood Institute's Framingham Heart Study: Design, Recruitment, and Initial Examination

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00689.X

Apolipoprotein E and its role in aging and survival

21 January 2018

1 reference

12 December 2020

Apolipoprotein E polymorphism and central nervous system tumors: correlation with cell proliferation indices and clinical outcome

1 reference

12 December 2020

Estimation of apolipoprotein E genotype-specific relative mortality risks from the distribution of genotypes in centenarians and middle-aged men: apolipoprotein E gene is a "frailty gene," not a "longevity gene"

1 reference

12 December 2020

Apolipoprotein E gene polymorphism and colorectal cancer: gender-specific modulation of risk and prognosis

1 reference

12 December 2020

ANTAGONISTIC PLEIOTROPY, MORTALITY SOURCE INTERACTIONS, AND THE EVOLUTIONARY THEORY OF SENESCENCE

1 reference

12 December 2020

Epidemiological approaches to heart disease: the Framingham Study

1 reference

12 December 2020

Low fibrosis progression of recurrent hepatitis C in apolipoprotein E epsilon4 carriers: relationship with the blood lipid profile

1 reference

12 December 2020

10.1111/J.1474-9726.2011.00689.X

Identifiers

DOI

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5 August 2017

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5 August 2017

1 reference