(Q34981539)

5 August 2017

title

Modulation of protease activated receptor 1 influences human metapneumovirus disease severity in a mouse model (English)

1 reference

5 August 2017

main subject

Human metapneumovirus

object named as

human metapneumovirus

1 reference

Nathalie Vergnolle

10

0 references

Nabil Seidah

object named as

Nabil G Seidah

9

0 references

Guy Boivin

12

object named as

Guy Boivin

1 reference

5 August 2017

2

Marie-Ève Hamelin

1 reference

5 August 2017

Laetitia Aerts

1

1 reference

5 August 2017

Chantal Rhéaume

3

1 reference

5 August 2017

Sophie Lavigne

4

1 reference

5 August 2017

Christian Couture

5

1 reference

5 August 2017

Woojin Kim

6

1 reference

5 August 2017

Delia Susan-Resiga

7

1 reference

5 August 2017

Annik Prat

8

1 reference

5 August 2017

Beatrice Riteau

11

1 reference

5 August 2017

language of work or name

English

0 references

publication date

28 August 2013

1 reference

5 August 2017

1 reference

5 August 2017

volume

8

1 reference

5 August 2017

issue

8

1 reference

5 August 2017

page(s)

e72529

1 reference

Creative Commons Attribution 4.0 International

5 August 2017

copyright license

start time

28 August 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3755973/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Granzyme A and thrombin differentially promote the release of interleukin-8 from alveolar epithelial A549 cells

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8 July 2018

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Pulmonary epithelium is a prominent source of proteinase-activated receptor-1-inducible CCL2 in pulmonary fibrosis

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8 July 2018

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8 July 2018

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8 July 2018

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Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Protease-activated receptor 1-selective antagonist SCH79797 inhibits cell proliferation and induces apoptosis by a protease-activated receptor 1-independent mechanism

8 July 2018

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SCH 79797, a selective PAR1 antagonist, limits myocardial ischemia/reperfusion injury in rat hearts

8 July 2018

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Induction of monocyte chemoattractant protein-1 release from A549 cells by agonists of protease-activated receptor-1 and -2.

8 July 2018

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8 July 2018

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8 July 2018

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Effect of ribavirin and glucocorticoid treatment in a mouse model of human metapneumovirus infection

8 July 2018

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8 July 2018

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The cotton rat (Sigmodon hispidus) is a permissive small animal model of human metapneumovirus infection, pathogenesis, and protective immunity

8 July 2018

1 reference

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Pathogenesis of human metapneumovirus lung infection in BALB/c mice and cotton rats

8 July 2018

1 reference

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A major role for proteolytic activity and proteinase-activated receptor-2 in the pathogenesis of infectious colitis

8 July 2018

1 reference

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The immune response to human metapneumovirus is associated with aberrant immunity and impaired virus clearance in BALB/c mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3755973

Proteinase-activated receptors: transducers of proteinase-mediated signaling in inflammation and immune response.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3755973

Human metapneumovirus persists in BALB/c mice despite the presence of neutralizing antibodies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3755973

Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3755973

Experimental human metapneumovirus infection of cynomolgus macaques (Macaca fascicularis) results in virus replication in ciliated epithelial cells and pneumocytes with associated lesions throughout the respiratory tract.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3755973

Protease-activated receptors: contribution to physiology and disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3755973

Clinical impact and diagnosis of human metapneumovirus infection

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3755973

Altered expression and in vivo lung function of protease-activated receptors during influenza A virus infection in mice.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3755973

Comparison of the inhibition of human metapneumovirus and respiratory syncytial virus by ribavirin and immune serum globulin in vitro

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3755973

Proteinase-activated receptor 1 activation induces epithelial apoptosis and increases intestinal permeability

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3755973

Human metapneumovirus infections in hospitalized children

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3755973

Respiratory tract reinfections by the new human Metapneumovirus in an immunocompromised child

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3755973

Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3755973

Signalling pathways induced by protease-activated receptors and integrins in T cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3755973

Proteinase-activated receptors.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3755973

Thrombin signalling and protease-activated receptors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3755973

Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3755973

Termination of signaling by protease-activated receptor-1 is linked to lysosomal sorting

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3755973

Proteinase-activated receptors: novel mechanisms of signaling by serine proteases.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3755973

Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3755973

An Outbreak of Severe Respiratory Tract Infection Due to Human Metapneumovirus in a Long-Term Care Facility

8 July 2018

1 reference

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A Summer Outbreak of Human Metapneumovirus Infection in a Long‐Term‐Care Facility

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0072529

Human metapneumovirus in a haematopoietic stem cell transplant recipient with fatal lower respiratory tract disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0072529

Pathology of human metapneumovirus infection: insights into the pathogenesis of a newly identified respiratory virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0072529

Detection of severe human metapneumovirus infection by real-time polymerase chain reaction and histopathological assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0072529

Immune response and alteration of pulmonary function after primary human metapneumovirus (hMPV) infection of BALB/c mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0072529

Human metapneumovirus infection induces long-term pulmonary inflammation associated with airway obstruction and hyperresponsiveness in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0072529

Successful outcome of human metapneumovirus (hMPV) pneumonia in a lung transplant recipient treated with intravenous ribavirin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0072529

Vorapaxar for secondary prevention of thrombotic events for patients with previous myocardial infarction: a prespecified subgroup analysis of the TRA 2°P-TIMI 50 trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0072529

Thrombin enhances herpes simplex virus infection of cells involving protease-activated receptor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0072529

Tissue factor and glycoprotein C on herpes simplex virus type 1 are protease-activated receptor 2 cofactors that enhance infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0072529

Immunization of macaques with formalin-inactivated human metapneumovirus induces hypersensitivity to hMPV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0072529

Thrombin regulates the function of human blood dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0072529

Protease-activated receptor 1 knockout reduces experimentally induced liver fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0072529

Modification of the cytoprotective protein C pathway during Dengue virus infection of human endothelial vascular cells.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3755973

Proteinase-activated receptor-1 is an anti-inflammatory signal for colitis mediated by a type 2 immune response

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3755973

Effects of ribavirin on cytokine production of recall antigens and phytohemaglutinin-stimulated peripheral blood mononuclear cells. (Inhibitory effects of ribavirin on cytokine production).

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3755973

Induction of IL-6 release from human T cells by PAR-1 and PAR-2 agonists

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24015257

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Development of a cotton rat-human metapneumovirus (hMPV) model for identifying and evaluating potential hMPV antivirals and vaccines

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24015257

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0072529

1 reference

5 August 2017

0 references

1 reference

5 August 2017

1 reference