(Q35067671)

6 August 2017

title

Furin is the major processing enzyme of the cardiac-specific growth factor bone morphogenetic protein 10. (English)

1 reference

6 August 2017

1 reference

Daniel Constam

9

0 references

Annik Prat

Annik Prat

11

0 references

Shoumo Bhattacharya

Shoumo Bhattacharya

10

0 references

Nabil Seidah

Nabil G Seidah

12

0 references

Dorota Szumska

Dorota Szumska

8

1 reference

ORCID Public Data File 2021

author name string

Delia Susan-Resiga

1

1 reference

6 August 2017

Rachid Essalmani

2

1 reference

6 August 2017

Josée Hamelin

3

1 reference

6 August 2017

Marie-Claude Asselin

4

1 reference

6 August 2017

Suzanne Benjannet

5

1 reference

6 August 2017

Ann Chamberland

6

1 reference

6 August 2017

Robert Day

7

1 reference

6 August 2017

language of work or name

English

0 references

publication date

5 May 2011

1 reference

Journal of Biological Chemistry

6 August 2017

published in

1 reference

6 August 2017

volume

286

1 reference

6 August 2017

issue

26

1 reference

6 August 2017

page(s)

22785-22794

1 reference

describes a project that uses

6 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3123046/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Proprotein convertase PC7 enhances the activation of the EGF receptor pathway through processing of the EGF precursor

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In vivo evidence that furin from hepatocytes inactivates PCSK9

8 July 2018

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The proprotein convertase PC7: unique zymogen activation and trafficking pathways

8 July 2018

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Expression, purification and osteogenic bioactivity of recombinant human BMP-4, -9, -10, -11 and -14.

8 July 2018

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Role of furin in granular acidification in the endocrine pancreas: identification of the V-ATPase subunit Ac45 as a candidate substrate

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123046

T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance

8 July 2018

1 reference

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Inhibition of Chikungunya virus infection in cultured human muscle cells by furin inhibitors: impairment of the maturation of the E2 surface glycoprotein

8 July 2018

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VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5

8 July 2018

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In vivo functions of the proprotein convertase PC5/6 during mouse development: Gdf11 is a likely substrate

8 July 2018

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The activation and physiological functions of the proprotein convertases

8 July 2018

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Overexpression of bone morphogenetic protein 10 in myocardium disrupts cardiac postnatal hypertrophic growth

8 July 2018

1 reference

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The cysteine-rich domain of the secreted proprotein convertases PC5A and PACE4 functions as a cell surface anchor and interacts with tissue inhibitors of metalloproteinases

8 July 2018

1 reference

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Identification of receptors and signaling pathways for orphan bone morphogenetic protein/growth differentiation factor ligands based on genomic analyses

8 July 2018

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Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia

8 July 2018

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BMP10 is essential for maintaining cardiac growth during murine cardiogenesis

8 July 2018

1 reference

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Furin at the cutting edge: from protein traffic to embryogenesis and disease

8 July 2018

1 reference

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Biosynthetic processing of the pro-alpha 1(V)2pro-alpha 2(V) collagen heterotrimer by bone morphogenetic protein-1 and furin-like proprotein convertases

8 July 2018

1 reference

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Inhibitory potency and specificity of subtilase-like pro-protein convertase (SPC) prodomains

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123046

Mutations within a furin consensus sequence block proteolytic release of ectodysplasin-A and cause X-linked hypohidrotic ectodermal dysplasia

8 July 2018

1 reference

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Evidence that furin is an authentic transforming growth factor-beta1-converting enzyme

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123046

The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters

8 July 2018

1 reference

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A genetic blueprint for cardiac development

8 July 2018

1 reference

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Polyarginines are potent furin inhibitors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123046

SPC4/PACE4 regulates a TGFbeta signaling network during axis formation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123046

Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123046

The prosegments of furin and PC7 as potent inhibitors of proprotein convertases. In vitro and ex vivo assessment of their efficacy and selectivity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123046

Heart specific expression of mouse BMP-10 a novel member of the TGF-beta superfamily

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123046

BMP-4 is proteolytically activated by furin and/or PC6 during vertebrate embryonic development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123046

In vitro cleavage of internally quenched fluorogenic human proparathyroid hormone and proparathyroid-related peptide substrates by furin. Generation of a potent inhibitor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123046

A role for PACE4 in the proteolytic activation of anthrax toxin protective antigen.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123046

Identification of the paired basic convertases implicated in HIV gp160 processing based on in vitro assays and expression in CD4(+) cell lines

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123046

Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123046

The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123046

Proteolytic activation of bacterial toxins by eukaryotic cells is performed by furin and by additional cellular proteases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123046

A mutation of furin causes the lack of precursor-processing activity in human colon carcinoma LoVo cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123046

A second mutant allele of furin in the processing-incompetent cell line, LoVo. Evidence for involvement of the homo B domain in autocatalytic activation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123046

Intracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surface

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123046

Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gp160

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123046

Altered processing of the neurotensin/neuromedin N precursor in PC2 knock down mice: a biochemical and immunohistochemical study

8 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.233577

The regulated cell surface zymogen activation of the proprotein convertase PC5A directs the processing of its secretory substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.233577

Mutation of an upstream cleavage site in the BMP4 prodomain leads to tissue-specific loss of activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.233577

A comprehensive study of the spatial and temporal expression of the col5a1 gene in mouse embryos: a clue for understanding collagen V function in developing connective tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.233577

Limited redundancy of the proprotein convertase furin in mouse liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.233577

Tissue-specific requirements for the proprotein convertase furin/SPC1 during embryonic turning and heart looping.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123046

Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase Furin.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123046

The neuroendocrine precursor 7B2 is a sulfated protein proteolytically processed by a ubiquitous furin-like convertase

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21550985

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M111.233577

1 reference

6 August 2017

1 reference

6 August 2017

1 reference