(Q34982853)

5 August 2017

Singly modified amikacin and tobramycin derivatives show increased rRNA A-site binding and higher potency against resistant bacteria (English)

1 reference

5 August 2017

1 reference

5

Victor Nizet

0 references

author name string

Richard J Fair

1

1 reference

5 August 2017

Lisa S McCoy

2

1 reference

5 August 2017

Mary E Hensler

3

1 reference

5 August 2017

Bernice Aguilar

4

1 reference

5 August 2017

Yitzhak Tor

6

1 reference

5 August 2017

language of work or name

1 reference

23 July 2014

1 reference

5 August 2017

1 reference

5 August 2017

9

1 reference

5 August 2017

9

1 reference

5 August 2017

2164-2171

1 reference

Designer aminoglycosides that selectively inhibit cytoplasmic rather than mitochondrial ribosomes show decreased ototoxicity: a strategy for the treatment of genetic diseases

5 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Aminoglycosides: how should we use them in the 21st century?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Polymyxins and analogues bind to ribosomal RNA and interfere with eukaryotic translation in vitro.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

10 x '20 Progress--development of new drugs active against gram-negative bacilli: an update from the Infectious Diseases Society of America

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Clinical relevance of the ESKAPE pathogens

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Aminoglycoside antibiotics in the 21st century.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Selectively guanidinylated aminoglycosides as antibiotics

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Antibiotics that target protein synthesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Fidaxomicin: first-in-class macrocyclic antibiotic

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Current use of aminoglycosides: indications, pharmacokinetics and monitoring for toxicity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Origins and evolution of antibiotic resistance

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Antibiotic selectivity for prokaryotic vs. eukaryotic decoding sites

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

FRET enabled real time detection of RNA-small molecule binding

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Conjugative plasmids: vessels of the communal gene pool

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Potential of old-generation antibiotics to address current need for new antibiotics

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Federal funding for the study of antimicrobial resistance in nosocomial pathogens: no ESKAPE

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Where have All the Antibiotics Gone?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Clinical and economic impact of common multidrug-resistant gram-negative bacilli

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Aminoglycoside antibiotics: old drugs and new therapeutic approaches

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Crystal structure of the bacterial ribosomal decoding site complexed with amikacin containing the gamma-amino-alpha-hydroxybutyryl (haba) group

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Aminoglycoside-induced reduction in nucleotide mobility at the ribosomal RNA A-site as a potentially key determinant of antibacterial activity.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Colistin: the revival of polymyxins for the management of multidrug-resistant gram-negative bacterial infections

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Trends in antimicrobial drug development: implications for the future

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Daptomycin: another novel agent for treating infections due to drug-resistant gram-positive pathogens

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Oxazolidinone Structure–Activity Relationships Leading to Linezolid

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Crystal structure of a complex between the aminoglycoside tobramycin and an oligonucleotide containing the ribosomal decoding a site

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Recognition of cognate transfer RNA by the 30S ribosomal subunit

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Enhanced RNA binding of dimerized aminoglycosides

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

BB-K 8, a new semisynthetic aminoglycoside antibiotic

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Interaction of antibiotics with functional sites in 16S ribosomal RNA

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298452

Evaluation of amphiphilic aminoglycoside-peptide triazole conjugates as antibacterial agents

8 July 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201402175

6''-Thioether tobramycin analogues: towards selective targeting of bacterial membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201402175

Site-selective displacement of tobramycin hydroxyls for preparation of antimicrobial cationic amphiphiles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201402175

CuAAC-mediated diversification of aminoglycoside-arginine conjugate mimics by non-reducing di- and trisaccharides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201402175

Design, synthesis, and antibacterial activities of conformationally constrained kanamycin A derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201402175

Synthesis of triazole-functionalized 2-DOS analogues and their evaluation as A-site binders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201402175

5-substituted, 6-substituted, and unsubstituted 3-heteroaromatic pyridine analogues of nicotine as selective inhibitors of cytochrome P-450 2A6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201402175

The multicopper oxidase of Pseudomonas aeruginosa is a ferroxidase with a central role in iron acquisition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201402175

21 January 2018

Identifiers

DOI

10.1002/CMDC.201402175

1 reference

5 August 2017

1 reference

5 August 2017

1 reference