(Q34992163)

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Group II metabotropic glutamate receptor type 2 allosteric potentiators prevent sodium lactate-induced panic-like response in panic-vulnerable rats.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22914798%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Group II metabotropic glutamate receptor type 2 allosteric potentiators prevent sodium lactate-induced panic-like response in panic-vulnerable rats (English)

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11 February 2020

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ChEBI release 2020-05-28

Philip L Johnson

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11 February 2020

Stephanie D. Fitz

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Stephanie D Fitz

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11 February 2020

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Eric A Engleman

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11 February 2020

Kjell A Svensson

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11 February 2020

Jeffrey M Schkeryantz

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11 February 2020

Anantha Shekhar

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11 February 2020

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21 August 2012

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11 February 2020

Journal of Psychopharmacology

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11 February 2020

27

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11 February 2020

2

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11 February 2020

152-161

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11 February 2020

Metabotropic glutamate receptors: from the workbench to the bedside

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8 July 2018

Changes in central sodium and not osmolarity or lactate induce panic-like responses in a model of panic disorder

1 reference

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8 July 2018

A key role for orexin in panic anxiety.

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8 July 2018

Current use of benzodiazepines in anxiety disorders.

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8 July 2018

World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the pharmacological treatment of anxiety, obsessive-compulsive and post-traumatic stress disorders - first revision

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8 July 2018

Neural pathways underlying lactate-induced panic.

1 reference

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8 July 2018

Evidence-based guidelines for the pharmacological treatment of anxiety disorders: recommendations from the British Association for Psychopharmacology

1 reference

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8 July 2018

Metabotropic glutamate 2 receptor potentiators: receptor modulation, frequency-dependent synaptic activity, and efficacy in preclinical anxiety and psychosis model(s).

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8 July 2018

Metabotropic glutamate receptors as novel targets for anxiety and stress disorders

1 reference

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8 July 2018

Critical role of dorsomedial hypothalamic nucleus in a wide range of behavioral circadian rhythms

1 reference

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8 July 2018

LY354740, an mGlu2/3 receptor agonist as a novel approach to treat anxiety/stress

1 reference

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8 July 2018

The Amygdala, Panic Disorder, and Cardiovascular Responses

1 reference

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8 July 2018

Anxiolytic effects of a novel group II metabotropic glutamate receptor agonist (LY354740) in the fear-potentiated startle paradigm in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

New molecular targets for antianxiety interventions

1 reference

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8 July 2018

Generalized anxiety disorder: comorbidity, comparative biology and treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

The dorsomedial hypothalamus and the response to stress: part renaissance, part revolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

The role of amygdala glutamate receptors in fear learning, fear-potentiated startle, and extinction

1 reference

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8 July 2018

Modeling panic attacks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

Neuroanatomical hypothesis of panic disorder, revised

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

Memantine is a clinically well tolerated N-methyl-D-aspartate (NMDA) receptor antagonist--a review of preclinical data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

The dorsomedial hypothalamic nucleus revisited: 1998 update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

Organization of inputs to the dorsomedial nucleus of the hypothalamus: a reexamination with Fluorogold and PHAL in the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

Anxiolytic and side-effect profile of LY354740: a potent, highly selective, orally active agonist for group II metabotropic glutamate receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

The circumventricular organs form a potential neural pathway for lactate sensitivity: implications for panic disorder.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

Lactate-induced anxiety after imipramine and diazepam treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

Design, synthesis, and pharmacological characterization of (+)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY354740): a potent, selective, and orally active group 2 metabotropic glutamate receptor agonist possessing anticonvulsant and anxioly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

Dorsomedial hypothalamic GABA dysfunction produces physiological arousal following sodium lactate infusions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

Organization of projections from the dorsomedial nucleus of the hypothalamus: a PHA-L study in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

Panic disorder: diagnosis, epidemiology, and clinical course.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

The metabotropic glutamate receptors, mGluR2 and mGluR3, show unique postsynaptic, presynaptic and glial localizations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

False suffocation alarms, spontaneous panics, and related conditions. An integrative hypothesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

Distribution of the messenger RNA for a metabotropic glutamate receptor, mGluR2, in the central nervous system of the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity Survey

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

Effects of antagonists at the NMDA receptor complex in two models of anxiety.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

The metabotropic glutamate receptors: structure and functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

The use of social interaction as a method for detecting anxiolytic activity of chlordiazepoxide-like drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

The epidemiology of anxiety and panic disorders: an update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

Injection of L-allylglycine into the posterior hypothalamus in rats causes decreases in local GABA which correlate with increases in heart rate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

An improved and rapid HPLC-EC method for the isocratic separation of amino acid neurotransmitters from brain tissue and microdialysis perfusates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

High sensitivity HPLC assay for GABA in brain dialysis studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

Synaptic activation of rat supraoptic neurons by osmotic stimulation of the organum vasculosum lamina terminalis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

Anxiolytic-like effects of the noncompetitive NMDA antagonist MK 801

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

8 July 2018

rCBF differences between panic disorder patients and control subjects during anticipatory anxiety and rest

1 reference

https://api.crossref.org/works/10.1177%2F0269881112454230

21 January 2018

Endomorphin 1- and endomorphin 2-like immunoreactive neurons in the hypothalamus send axons to the parabrachial nucleus in the rat.

1 reference

https://api.crossref.org/works/10.1177%2F0269881112454230

21 January 2018

Different distributions of GAD65 and GAD67 mRNAs suggest that the two glutamate decarboxylases play distinctive functional roles.

1 reference

https://api.crossref.org/works/10.1177%2F0269881112454230

21 January 2018

Reductions in occipital cortex GABA levels in panic disorder detected with 1h-magnetic resonance spectroscopy

1 reference

https://api.crossref.org/works/10.1177%2F0269881112454230

21 January 2018

Characterization of the neurochemical content of neuronal populations of the lamina terminalis activated by acute hydromineral challenge

1 reference

https://api.crossref.org/works/10.1177%2F0269881112454230

21 January 2018

Role of glutamate ionotropic receptors in the dorsomedial hypothalamic nucleus on anxiety and locomotor behavior

1 reference

https://api.crossref.org/works/10.1177%2F0269881112454230

21 January 2018

Panic-prone state induced in rats with GABA dysfunction in the dorsomedial hypothalamus is mediated by NMDA receptors.

1 reference

https://api.crossref.org/works/10.1177%2F0269881112454230

21 January 2018

Cost-effectiveness and cost offset of a collaborative care intervention for primary care patients with panic disorder

1 reference

https://api.crossref.org/works/10.1177%2F0269881112454230

21 January 2018

Sodium lactate elicits anxiety in rats after repeated GABA receptor blockade in the basolateral amygdala

1 reference

https://api.crossref.org/works/10.1177%2F0269881112454230

21 January 2018

Regulation of anxiety by GABAA receptors in the rat amygdala.

1 reference

https://api.crossref.org/works/10.1177%2F0269881112454230

21 January 2018

Evidence of a suffocation alarm system within the periaqueductal gray matter of the rat.

1 reference

https://api.crossref.org/works/10.1177%2F0269881112454230

21 January 2018

Angiotensin-II is a putative neurotransmitter in lactate-induced panic-like responses in rats with disruption of GABAergic inhibition in the dorsomedial hypothalamus.

1 reference

https://api.crossref.org/works/10.1177%2F0269881112454230

21 January 2018

Dorsomedial hypothalamic GABA regulates anxiety in the social interaction test

1 reference

https://api.crossref.org/works/10.1177%2F0269881112454230

21 January 2018

LY354740, a potent group II metabotropic glutamate receptor agonist prevents lactate-induced panic-like response in panic-prone rats

1 reference

https://api.crossref.org/works/10.1177%2F0269881112454230

21 January 2018

The group II metabotropic glutamate receptor agonist (-)-2-oxa-4-aminobicyclo[3.1.0.]hexane-4,6-dicarboxylate (LY379268) and clozapine reverse phencyclidine-induced behaviors in monoamine-depleted rats

1 reference

https://api.crossref.org/works/10.1177%2F0269881112454230

21 January 2018

Some forebrain mechanisms involved in expression of rage with special reference to suppression of angry behavior.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

26 October 2018

Descending pathways mediating cardiovascular response from dorsomedial hypothalamic nucleus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

26 October 2018

Biological accompaniments of lactate-induced panic.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300988

26 October 2018

Dorsomedial hypothalamic sites where disinhibition evokes tachycardia correlate with location of raphe-projecting neurons

1 reference

https://api.crossref.org/works/10.1177%2F0269881112454230

21 January 2018

Connections of the rat lateral septal complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/22914798

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of metabotropic glutamate 2 and 3 receptors in the rat forebrain: Implication in emotional responses and central disinhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/22914798

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of the mRNA for a metabotropic glutamate receptor (mGluR3) in the rat brain: an in situ hybridization study

1 reference

https://pubmed.ncbi.nlm.nih.gov/22914798

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pre- and postsynaptic localization of a metabotropic glutamate receptor, mGluR2, in the rat brain: an immunohistochemical study with a monoclonal antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/22914798

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anxiogenic effects of CO2 and hyperventilation in patients with panic disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/22914798

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Topographic organization of respiratory responses to glutamate microstimulation of the parabrachial nucleus in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/22914798

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1177/0269881112454230

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22914798%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22914798%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22914798%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

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