(Q35005209)

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Combinatorial effect of two framework mutations (E119V and I222L) in the neuraminidase active site of H3N2 influenza virus on resistance to oseltamivir

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Europe PubMed Central

PubMed publication ID

5 August 2017

Combinatorial effect of two framework mutations (E119V and I222L) in the neuraminidase active site of H3N2 influenza virus on resistance to oseltamivir (English)

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Europe PubMed Central

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5 August 2017

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Mathilde Richard

object named as

Mathilde Richard

1

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Bruno Lina

10

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Olivier Ferraris

2

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Europe PubMed Central

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5 August 2017

Alexandra Erny

3

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Europe PubMed Central

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5 August 2017

Mendy Barthélémy

4

1 reference

Europe PubMed Central

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5 August 2017

Aurélien Traversier

5

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Europe PubMed Central

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5 August 2017

Murielle Sabatier

6

1 reference

Europe PubMed Central

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5 August 2017

Alan Hay

7

1 reference

Europe PubMed Central

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5 August 2017

Yi Pu Lin

8

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Europe PubMed Central

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5 August 2017

Rupert J Russell

9

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5 August 2017

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publication date

21 March 2011

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5 August 2017

Antimicrobial Agents and Chemotherapy

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Europe PubMed Central

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5 August 2017

55

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Europe PubMed Central

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5 August 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

2942-2952

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Oseltamivir-resistant influenza A(H1N1) viruses in south of France, 2007/2009.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

In vitro characterization of naturally occurring influenza H3NA- viruses lacking the NA gene segment: toward a new mechanism of viral resistance?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Permissive secondary mutations enable the evolution of influenza oseltamivir resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Detection of E119V and E119I mutations in influenza A (H3N2) viruses isolated from an immunocompromised patient: challenges in diagnosis of oseltamivir resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Oseltamivir-resistant 2009 pandemic influenza A (H1N1) virus infection in two summer campers receiving prophylaxis--North Carolina, 2009.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

In vitro generation of neuraminidase inhibitor resistance in A(H5N1) influenza viruses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Emergence and spread of oseltamivir-resistant A(H1N1) influenza viruses in Oceania, South East Asia and South Africa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Oseltamivir-resistant influenza virus A (H1N1), Europe, 2007-08 season

1 reference

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8 July 2018

Oseltamivir-resistant influenza A viruses are transmitted efficiently among guinea pigs by direct contact but not by aerosol.

1 reference

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8 July 2018

Enzymatic properties of the neuraminidase of seasonal H1N1 influenza viruses provide insights for the emergence of natural resistance to oseltamivir

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Surveillance for neuraminidase inhibitor resistance among human influenza A and B viruses circulating worldwide from 2004 to 2008.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Impact of influenza A virus neuraminidase mutations on the stability, activity, and sensibility of the neuraminidase to neuraminidase inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Mutations of neuraminidase implicated in neuraminidase inhibitors resistance

1 reference

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8 July 2018

Inefficient transmission of H5N1 influenza viruses in a ferret contact model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Emergence of influenza B viruses with reduced sensitivity to neuraminidase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Impact of neuraminidase mutations conferring influenza resistance to neuraminidase inhibitors in the N1 and N2 genetic backgrounds.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Characterization of drug-resistant recombinant influenza A/H1N1 viruses selected in vitro with peramivir and zanamivir

1 reference

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8 July 2018

Natural variation can significantly alter the sensitivity of influenza A (H5N1) viruses to oseltamivir.

1 reference

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8 July 2018

The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Importance of neuraminidase active-site residues to the neuraminidase inhibitor resistance of influenza viruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Detection of influenza viruses resistant to neuraminidase inhibitors in global surveillance during the first 3 years of their use.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

The guinea pig as a transmission model for human influenza viruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: design, synthesis, and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Susceptibilities of antiviral-resistant influenza viruses to novel neuraminidase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Neuraminidase inhibitor-resistant influenza viruses may differ substantially in fitness and transmissibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Characterization of recombinant influenza B viruses with key neuraminidase inhibitor resistance mutations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Molecular mechanisms of influenza virus resistance to neuraminidase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Overexpression of the alpha-2,6-sialyltransferase in MDCK cells increases influenza virus sensitivity to neuraminidase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Evaluation of neuraminidase enzyme assays using different substrates to measure susceptibility of influenza virus clinical isolates to neuraminidase inhibitors: report of the neuraminidase inhibitor susceptibility network.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Mechanism by which mutations at his274 alter sensitivity of influenza a virus n1 neuraminidase to oseltamivir carboxylate and zanamivir

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Influenza virus carrying an R292K mutation in the neuraminidase gene is not transmitted in ferrets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Selection of influenza virus mutants in experimentally infected volunteers treated with oseltamivir

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

A DNA transfection system for generation of influenza A virus from eight plasmids

1 reference

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8 July 2018

Characterization of human influenza virus variants selected in vitro in the presence of the neuraminidase inhibitor GS 4071.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Identification of GS 4104 as an orally bioavailable prodrug of the influenza virus neuraminidase inhibitor GS 4071.

1 reference

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Catalytic and framework mutations in the neuraminidase active site of influenza viruses that are resistant to 4-guanidino-Neu5Ac2en.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Characterization of mutants of influenza A virus selected with the neuraminidase inhibitor 4-guanidino-Neu5Ac2en

1 reference

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Rational design of potent sialidase-based inhibitors of influenza virus replication

1 reference

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8 July 2018

Sequence and structure alignment of paramyxovirus hemagglutinin-neuraminidase with influenza virus neuraminidase.

1 reference

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Molecular modeling studies on ligand binding to sialidase from influenza virus and the mechanism of catalysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Influenza type A virus neuraminidase does not play a role in viral entry, replication, assembly, or budding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Structure of the influenza virus glycoprotein antigen neuraminidase at 2.9 A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

8 July 2018

Structure of the catalytic and antigenic sites in influenza virus neuraminidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

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Characterization of temperature sensitive influenza virus mutants defective in neuraminidase

1 reference

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Three-dimensional structure of neuraminidase of subtype N9 from an avian influenza virus.

1 reference

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Hemagglutinins from two influenza virus variants bind to sialic acid derivatives with millimolar dissociation constants: a 500-MHz proton nuclear magnetic resonance study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

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Refined atomic structures of N9 subtype influenza virus neuraminidase and escape mutants

1 reference

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Three-dimensional structure of the neuraminidase of influenza virus A/Tokyo/3/67 at 2.2 A resolution

1 reference

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Evidence for a sialosyl cation transition-state complex in the reaction of sialidase from influenza virus

1 reference

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8 July 2018

The structure of the complex between influenza virus neuraminidase and sialic acid, the viral receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

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Inhibition of influenza virus replication in tissue culture by 2-deoxy-2,3-dehydro-N-trifluoroacetylneuraminic acid (FANA): mechanism of action

1 reference

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Effect of the neuraminidase mutation H274Y conferring resistance to oseltamivir on the replicative capacity and virulence of old and recent human influenza A(H1N1) viruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

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Emergence of H274Y oseltamivir-resistant A(H1N1) influenza viruses in Japan during the 2008-2009 season

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101467

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Surveillance for neuraminidase-inhibitor-resistant influenza viruses in Japan, 1996-2007.

1 reference

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Infections with oseltamivir-resistant influenza A(H1N1) virus in the United States

1 reference

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Detection of human influenza A (H1N1) and B strains with reduced sensitivity to neuraminidase inhibitors.

1 reference

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Activity of the neuraminidase inhibitor A-315675 against oseltamivir-resistant influenza neuraminidases of N1 and N2 subtypes

1 reference

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Sensitivity of influenza viruses to zanamivir and oseltamivir: a study performed on viruses circulating in France prior to the introduction of neuraminidase inhibitors in clinical practice

1 reference

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1 reference

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A reverse genetics study of resistance to neuraminidase inhibitors in an influenza A/H1N1 virus.

1 reference

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Resistant influenza A viruses in children treated with oseltamivir: descriptive study

1 reference

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Susceptibility of human influenza viruses from Australasia and South East Asia to the neuraminidase inhibitors zanamivir and oseltamivir

1 reference

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Influenza virus carrying neuraminidase with reduced sensitivity to oseltamivir carboxylate has altered properties in vitro and is compromised for infectivity and replicative ability in vivo

1 reference

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26 October 2018

Characterization of multidrug-resistant influenza A/H3N2 viruses shed during 1 year by an immunocompromised child

1 reference

https://pubmed.ncbi.nlm.nih.gov/21422222

12 December 2020

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Identifiers

10.1128/AAC.01699-10

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

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