(Q35008879)

English

Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibition by 4-hydroxynonenal leads to increased Akt activation in hepatocytes

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scholarly article

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Europe PubMed Central

PubMed publication ID

5 August 2017

Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibition by 4-hydroxynonenal leads to increased Akt activation in hepatocytes (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

6

object named as

Numsen Hail

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1

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Colin T Shearn

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author name string

Colin T Shearn

1

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Rebecca L Smathers

2

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Benjamin J Stewart

3

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Kristofer S Fritz

4

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

James J Galligan

5

1 reference

Europe PubMed Central

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5 August 2017

Dennis R Petersen

7

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

publication date

17 March 2011

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Europe PubMed Central

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5 August 2017

Molecular Pharmacology

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Europe PubMed Central

PubMed publication ID

5 August 2017

79

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

941-952

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3102545/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Role of TAPP1 and TAPP2 adaptor binding to PtdIns(3,4)P2 in regulating insulin sensitivity defined by knock-in analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102545

8 July 2018

The critical role of AKT2 in hepatic steatosis induced by PTEN loss

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102545

8 July 2018

Physiological regulation of Akt activity and stability.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102545

8 July 2018

Akt2 is required for hepatic lipid accumulation in models of insulin resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102545

8 July 2018

Lipid aldehyde-mediated cross-linking of apolipoprotein B-100 inhibits secretion from HepG2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102545

8 July 2018

Dissecting the role of the 3-phosphoinositide-dependent protein kinase-1 (PDK1) signalling pathways.

1 reference

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8 July 2018

Severe liver steatosis correlates with nitrosative and oxidative stress in rats

1 reference

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8 July 2018

4-hydroxynonenal: a membrane lipid oxidation product of medicinal interest.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102545

8 July 2018

Reactive aldehyde modification of thioredoxin-1 activates early steps of inflammation and cell adhesion

1 reference

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8 July 2018

Carbonylation of adipose proteins in obesity and insulin resistance: identification of adipocyte fatty acid-binding protein as a cellular target of 4-hydroxynonenal

1 reference

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8 July 2018

Inhibition of thioredoxin and thioredoxin reductase by 4-hydroxy-2-nonenal in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102545

8 July 2018

Redox regulation of PTEN by S-nitrosothiols

1 reference

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8 July 2018

Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102545

8 July 2018

Regulation of glycogen synthase kinase-3beta by products of lipid peroxidation in human neuroblastoma cells

1 reference

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8 July 2018

Redox regulation of PTEN and protein tyrosine phosphatases in H(2)O(2) mediated cell signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102545

8 July 2018

Redox regulation of PI 3-kinase signalling via inactivation of PTEN

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102545

8 July 2018

TAPP1 and TAPP2 are targets of phosphatidylinositol 3-kinase signaling in B cells: sustained plasma membrane recruitment triggered by the B-cell antigen receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102545

8 July 2018

Reversible inactivation of the tumor suppressor PTEN by H2O2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102545

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Nile Red binding to HepG2 cells: an improved assay for in vitro studies of hepatosteatosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102545

8 July 2018

Phosphorylation of the PTEN tail acts as an inhibitory switch by preventing its recruitment into a protein complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102545

8 July 2018

Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102545

8 July 2018

The multiple roles of PTEN in tumor suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102545

8 July 2018

Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102545

8 July 2018

Formation and export of the glutathione conjugate of 4-hydroxy-2, 3-E-nonenal (4-HNE) in hepatoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102545

8 July 2018

In situ detection of lipid peroxidation by-products in chronic liver diseases

1 reference

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8 July 2018

Experimental liver cirrhosis induced by alcohol and iron

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102545

8 July 2018

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102545

8 July 2018

Oxidative stress and steatosis are cofactors of liver injury in primary biliary cirrhosis

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Decreased expression of peroxiredoxin 6 in a mouse model of ethanol consumption

1 reference

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26 October 2018

Residue-specific adduction of tubulin by 4-hydroxynonenal and 4-oxononenal causes cross-linking and inhibits polymerization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102545

26 October 2018

Cysteine modification by lipid peroxidation products inhibits protein disulfide isomerase

1 reference

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26 October 2018

Susceptibility of actin to modification by 4-hydroxy-2-nonenal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102545

26 October 2018

Protein phosphatase 2A-linked and -unlinked caspase-dependent pathways for downregulation of Akt kinase triggered by 4-hydroxynonenal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102545

26 October 2018

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26 October 2018

4-hydroxynonenal induces mitochondrial oxidative stress, apoptosis and expression of glutathione S-transferase A4-4 and cytochrome P450 2E1 in PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21415306

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based on heuristic

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Cytotoxic aldehydes originating from the peroxidation of liver microsomal lipids. Identification of 4,5-dihydroxydecenal

1 reference

https://pubmed.ncbi.nlm.nih.gov/21415306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The hepatocellular metabolism of 4-hydroxynonenal by alcohol dehydrogenase, aldehyde dehydrogenase, and glutathione S-transferase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21415306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Co-metabolism of ethanol, ethanol-derived acetaldehyde, and 4-hydroxynonenal in isolated rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21415306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatocyte-specific Pten-deficient mice as a novel model for nonalcoholic steatohepatitis and hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21415306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1124/MOL.110.069534

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

ResearchGate publication ID

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