(Q35010977)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21498508%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

title

Intestinal hypoxia-inducible factor-2alpha (HIF-2alpha) is critical for efficient erythropoiesis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21498508%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21498508%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

author name string

Erik R Anderson

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21498508%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Yatrik M Shah

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21498508%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

language of work or name

English

0 references

publication date

15 April 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21498508%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

28 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21498508%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

volume

286

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21498508%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

issue

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21498508%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

page(s)

19533-19540

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21498508%20AND%20SRC:MED&resulttype=core&format=json

Hypoxia-inducible factor-2α mediates the adaptive increase of intestinal ferroportin during iron deficiency in mice

28 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

Cellular hypoxia of pancreatic beta-cells due to high levels of oxygen consumption for insulin secretion in vitro

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

During EPO or anemia challenge, erythroid progenitor cells transit through a selectively expandable proerythroblast pool

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

Iron Loading and Overloading due to Ineffective Erythropoiesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

Erythropoiesis stimulating agents and anaemia of end-stage renal disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

HIF-2alpha, but not HIF-1alpha, promotes iron absorption in mice.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

Intestinal hypoxia-inducible transcription factors are essential for iron absorption following iron deficiency

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

Duodenal cytochrome B expression stimulates iron uptake by human intestinal epithelial cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

Hypoxia-inducible factor augments experimental colitis through an MIF-dependent inflammatory signaling cascade.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

Erythropoietin mediates hepcidin expression in hepatocytes through EPOR signaling and regulation of C/EBPalpha

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

Effect of erythropoietin on hepcidin, DMT1 with IRE, and hephaestin gene expression in duodenum of rats

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

Hepcidin inhibits apical iron uptake in intestinal cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs).

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

The role of erythropoietin therapy in the critically ill.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

Iron Imports. II. Iron uptake at the apical membrane in the intestine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

Hepcidin in iron overload disorders

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

Measurement of absolute oxygen levels in cells and tissues using oxygen sensors and 2-nitroimidazole EF5.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

An iron-regulated ferric reductase associated with the absorption of dietary iron

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

Hepcidin, a urinary antimicrobial peptide synthesized in the liver

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

Pathophysiology of thalassaemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

A novel mammalian iron-regulated protein involved in intracellular iron metabolism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

Cloning and characterization of a mammalian proton-coupled metal-ion transporter

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

Requirement for JAK2 in erythropoietin-induced signalling pathways

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103332

Regulation of erythropoietin production

8 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.238667

Tissue-specific changes in iron metabolism genes in mice following phenylhydrazine-induced haemolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.238667

Intestinal DMT1 cotransporter is down-regulated by hepcidin via proteasome internalization and degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.238667

Evidence for differential effects of hepcidin in macrophages and intestinal epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.238667

Effect of hepcidin on intestinal iron absorption in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.238667

Use of 2-nitroimidazoles as bioreductive markers for tumour hypoxia

21 January 2018

1 reference

12 December 2020

A simple technique for measuring storage iron concentrations in formalinised liver samples

1 reference

12 December 2020

Identification of HIF2alpha as an important STAT5 target gene in human hematopoietic stem cells

1 reference

12 December 2020

Transferrin receptor distribution and regulation in the rat small intestine. Effect of iron stores and erythropoiesis

1 reference

12 December 2020

IRON METABOLISM IN RATS WITH PHENYLHYDRAZINE-INDUCED HEMOLYTIC DISEASE

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M111.238667

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21498508%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21498508%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

PubMed publication ID

21498508

1 reference