(Q35015483)

5 August 2017

title

Molecular Validation of PACE4 as a Target in Prostate Cancer (English)

1 reference

5 August 2017

1 reference

François D'Anjou

1

1 reference

5 August 2017

Sophie Routhier

2

1 reference

5 August 2017

Jean-Pierre Perreault

3

1 reference

5 August 2017

Alain Latil

4

1 reference

5 August 2017

David Bonnel

5

1 reference

5 August 2017

Isabelle Fournier

6

1 reference

5 August 2017

Michel Salzet

7

1 reference

5 August 2017

Robert Day

8

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5 August 2017

publication date

1 June 2011

1 reference

5 August 2017

published in

Translational Oncology

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5 August 2017

volume

4

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5 August 2017

issue

3

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5 August 2017

page(s)

157-172

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describes a project that uses

5 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3104696/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Investigating a New Generation of Ribozymes in Order to Target HCV

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8 July 2018

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Identification of the GATA factor TRPS1 as a repressor of the osteocalcin promoter

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Trps1 deficiency enlarges the proliferative zone of growth plate cartilage by upregulation of Pthrp

8 July 2018

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A small-molecule furin inhibitor inhibits cancer cell motility and invasiveness

8 July 2018

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The activation and physiological functions of the proprotein convertases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Expression and characterization of a human BMP-7 variant with improved biochemical properties

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Proteomic analysis of proteins regulated by TRPS1 transcription factor in DU145 prostate cancer cells.

8 July 2018

1 reference

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8 July 2018

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Identification of inhibitors using a cell-based assay for monitoring Golgi-resident protease activity

8 July 2018

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8 July 2018

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Furin regulates the intracellular activation and the uptake rate of cell surface-associated MT1-MMP.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Destroying RNA as a therapeutic approach

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Abnormal expression and processing of the proprotein convertases PC1 and PC2 in human colorectal liver metastases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Inhibitors of proprotein convertases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Proprotein convertases: "master switches" in the regulation of tumor growth and progression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

PACE4 expression in mouse basal keratinocytes results in basement membrane disruption and acceleration of tumor progression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Regulation of the stepwise proteolytic cleavage and secretion of PDGF-B by the proprotein convertases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Cutting back on pro-protein convertases: the latest approaches to pharmacological inhibition

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Target-dependent on/off switch increases ribozyme fidelity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

The TRPS1 transcription factor: androgenic regulation in prostate cancer and high expression in breast cancer.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

MUC1 expression in human prostate cancer cell lines and primary tumors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Silencing of SPC2 expression using an engineered delta ribozyme in the mouse betaTC-3 endocrine cell line

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

The atypical GATA protein TRPS1 represses androgen-induced prostate-specific antigen expression in LNCaP prostate cancer cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

TACE/ADAM-17 maturation and activation of sheddase activity require proprotein convertase activity.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Novel insights into cadherin processing by subtilisin-like convertases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Increased furin activity enhances the malignant phenotype of human head and neck cancer cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Prohormone convertase furin has a role in gastric cancer cell proliferation with parathyroid hormone-related peptide in a reciprocal manner

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Proprotein convertases in tumor progression and malignancy: novel targets in cancer therapy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Structure and function of GC79/TRPS1, a novel androgen-repressible apoptosis gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Significance analysis of microarrays applied to the ionizing radiation response

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Transcriptional repression and developmental functions of the atypical vertebrate GATA protein TRPS1.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Evidence that furin is an authentic transforming growth factor-beta1-converting enzyme

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Comparative characterization of two forms of recombinant human SPC1 secreted from Schneider 2 cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

8 July 2018

The Hallmarks of Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Expression of PACE4 in chemically induced carcinomas is associated with spindle cell tumor conversion and increased invasive ability

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Pro-protein convertase gene expression in human breast cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Comparative analysis of expression of the proprotein convertases furin, PACE4, PC1 and PC2 in human lung tumours

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

cDNA structure, tissue distribution, and chromosomal localization of rat PC7, a novel mammalian proprotein convertase closest to yeast kexin-like proteinases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

The TNM classification of prostate cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Distribution and regulation of the prohormone convertases PC1 and PC2 in the rat pituitary.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Targeted production of proprotein convertase PC1 enhances mammary development and tumorigenesis in transgenic mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

The regulated cell surface zymogen activation of the proprotein convertase PC5A directs the processing of its secretory substrates

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Trps1 regulates proliferation and apoptosis of chondrocytes through Stat3 signaling.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Increased expression of the pro-protein convertase furin predicts decreased survival in ovarian cancer.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Engineering of alpha1-antitrypsin variants selective for subtilisin-like proprotein convertases PACE4 and PC6: importance of the P2' residue in stable complex formation of the serpin with proprotein convertase.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Functional characterization of the SOFA delta ribozyme

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Extensive analysis of the 7q31 region in human prostate tumors supports TES as the best candidate tumor suppressor gene.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Epigenetic regulation of proprotein convertase PACE4 gene expression in human ovarian cancer cells

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Proprotein convertases regulate activity of prostate epithelial cell differentiation markers and are modulated in human prostate cancer cells

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Inhibition of furin-mediated processing results in suppression of astrocytoma cell growth and invasiveness.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Elevated furin expression in aggressive human head and neck tumors and tumor cell lines

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

Proprotein convertases promote processing of VEGF-D, a critical step for binding the angiogenic receptor VEGFR-2

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104696

MUC1 Expression in Prostate Carcinoma: Correlation with Grade and Stage

9 December 2018

1 reference

12 December 2020

MUC1, MUC2, MUC4, MUC5AC and MUC6 Expression in the Progression of Prostate Cancer

1 reference

12 December 2020

The histology and prognosis of prostatic cancer

1 reference

12 December 2020

Proprotein processing activity and cleavage site selectivity of the Kex2-like endoprotease PACE4

1 reference

12 December 2020

Protease inhibitors suppress in vitro growth of human small cell lung cancer

1 reference

12 December 2020

Cellular localization of the prohormone convertases in the hypothalamic paraventricular and supraoptic nuclei: selective regulation of PC1 in corticotrophin-releasing hormone parvocellular neurons mediated by glucocorticoids

1 reference

12 December 2020

Identifiers

DOI

10.1593/TLO.10295

1 reference

release_pqiwl5cgpjgbznfxf2gt2cekfy

5 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/pqiwl5cgpjgbznfxf2gt2cekfy

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3104696

1 reference

5 August 2017

1 reference