(Q21261225)

5 July 2017

title

Abnormal expression and processing of the proprotein convertases PC1 and PC2 in human colorectal liver metastases (English)

1 reference

5 July 2017

Nabil Seidah

9

Nabil

Seidah

1 reference

Dimensions

18 August 2022

8

Michel Chrétien

Michel

Chrétien

2 references

5 July 2017

18 August 2022

George N Tzimas

1

George N

Tzimas

2 references

5 July 2017

18 August 2022

Eric Chevet

2

Eric

Chevet

2 references

5 July 2017

18 August 2022

Sarah Jenna

3

Sarah

Jenna

2 references

5 July 2017

18 August 2022

Duc Thang Nguyên

4

Duc Thang

Nguyên

2 references

5 July 2017

18 August 2022

Abdel M Khatib

5

Abdel M

Khatib

2 references

5 July 2017

18 August 2022

Victoria Marcus

6

Victoria

Marcus

2 references

5 July 2017

18 August 2022

Yi Zhang

7

Yi

Zhang

2 references

5 July 2017

18 August 2022

Peter Metrakos

10

Peter

Metrakos

2 references

5 July 2017

18 August 2022

language of work or name

English

0 references

publication date

17 November 2005

1 reference

5 July 2017

1 reference

5 July 2017

volume

5

1 reference

5 July 2017

issue

1

0 references

page(s)

149

1 reference

Neuroendocrine secretory protein 7B2: structure, expression and functions

5 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310616

Mammalian subtilisin/kexin isozyme SKI-1: A widely expressed proprotein convertase with a unique cleavage specificity and cellular localization

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310616

Isolation of the human PC6 gene encoding the putative host protease for HIV-1 gp160 processing in CD4+ T lymphocytes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310616

The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310616

Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310616

The neuroendocrine protein 7B2 is required for peptide hormone processing in vivo and provides a novel mechanism for pituitary Cushing's disease

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310616

Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310616

Severe block in processing of proinsulin to insulin accompanied by elevation of des-64,65 proinsulin intermediates in islets of mice lacking prohormone convertase 1/3.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310616

Elevated expression of proprotein convertases alters breast cancer cell growth in response to estrogen and tamoxifen

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310616

The subtilisin/kexin family of precursor convertases. Emphasis on PC1, PC2/7B2, POMC and the novel enzyme SKI-1.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310616

The SAAS granin exhibits structural and functional homology to 7B2 and contains a highly potent hexapeptide inhibitor of PC1.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310616

PC1 and PC2 are proprotein convertases capable of cleaving proopiomelanocortin at distinct pairs of basic residues

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310616

The proteolytic processing of pro-platelet-derived growth factor-A at RRKR(86) by members of the proprotein convertase family is functionally correlated to platelet-derived growth factor-A-induced functions and tumorigenicity.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310616

Evidence that PC2 is the endogenous pro-neurotensin convertase in rMTC 6-23 cells and that PC1- and PC2-transfected PC12 cells differentially process pro-neurotensin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310616

Immunohistochemical localization of the pro-peptide processing enzymes PC1/PC3 and PC2 in the human anal canal

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310616

Effect of LHRH on plasma 7B2 in patients with gonadotropin-producing pituitary adenomas

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310616

Expression of human prohormone convertase PC2 in a baculovirus-insect cell system.

30 May 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-5-149

Structure of the gene for the testis-specific proprotein convertase 4 and of its alternate messenger RNA isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-5-149

Human dermal fibroblasts express prohormone convertases 1 and 2 and produce proopiomelanocortin-derived peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-5-149

Inhibition of proprotein convertases is associated with loss of growth and tumorigenicity of HT-29 human colon carcinoma cells: importance of insulin-like growth factor-1 (IGF-1) receptor processing in IGF-1-mediated functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-5-149

Elevated furin expression in aggressive human head and neck tumors and tumor cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-5-149

The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-5-149

7B2, a possible marker for nonfunctioning pancreatic islet cell tumor

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16293189

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Proprotein convertases (PC1/PC3 and PC2) in normal and neoplastic human tissues: their use as markers of neuroendocrine differentiation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16293189

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Neurotensin and a non-peptide neurotensin receptor antagonist control human colon cancer cell growth in cell culture and in cells xenografted into nude mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16293189

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1471-2407-5-149

1 reference

5 July 2017

0 references

1 reference

5 July 2017

1 reference