(Q35017231)

5 August 2017

title

Therapeutic potential of histamine H3 receptor agonist for the treatment of obesity and diabetes mellitus (English)

1 reference

5 August 2017

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Ryo Yoshimoto

1

1 reference

5 August 2017

Yasuhisa Miyamoto

2

1 reference

5 August 2017

Ken Shimamura

3

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5 August 2017

Akane Ishihara

4

1 reference

5 August 2017

Kazuhiko Takahashi

5

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5 August 2017

Hidehito Kotani

6

1 reference

5 August 2017

Airu S Chen

7

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5 August 2017

Howard Y Chen

8

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5 August 2017

Douglas J Macneil

9

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5 August 2017

Akio Kanatani

10

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5 August 2017

Shigeru Tokita

11

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5 August 2017

language of work or name

English

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publication date

5 September 2006

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Proceedings of the National Academy of Sciences of the United States of America

5 August 2017

published in

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5 August 2017

volume

103

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5 August 2017

issue

37

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5 August 2017

page(s)

13866-13871

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A neuropeptide Y Y5 antagonist selectively ameliorates body weight gain and associated parameters in diet-induced obese mice

5 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

Influence of a selective histamine H3 receptor antagonist on hypothalamic neural activity, food intake and body weight

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

Anatomy and regulation of the central melanocortin system

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

Assessment of pharmacology and potential anti-obesity properties of H3 receptor antagonists/inverse agonists

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

The histamine H3 receptor: from gene cloning to H3 receptor drugs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

Acute wake-promoting actions of JNJ-5207852, a novel, diamine-based H3 antagonist

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

A simple method for the isolation and purification of total lipides from animal tissues

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

Hyperleptinemia, visceral adiposity, and decreased glucose tolerance in mice with a targeted disruption of the histidine decarboxylase gene.

8 July 2018

1 reference

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Minireview: From anorexia to obesity--the yin and yang of body weight control

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

Targeted disruption of H3 receptors results in changes in brain histamine tone leading to an obese phenotype

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

Genetics and pathophysiology of human obesity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

Hypothalamic histamine neurons activate lipolysis in rat adipose tissue.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

Targeted disruption of histamine H1-receptor attenuates regulatory effects of leptin on feeding, adiposity, and UCP family in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

Obesity and the regulation of energy balance

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

Bodyweight gain with atypical antipsychotics. A comparative review

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

The physiology of brain histamine.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

Diseases of liporegulation: new perspective on obesity and related disorders

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

Transgenic study of energy homeostasis equation: implications and confounding influences

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

Cloning and functional expression of the human histamine H3 receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

Thioperamide, a histamine H3 receptor antagonist, powerfully suppresses peptide YY-induced food intake in rats.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

Interacting appetite-regulating pathways in the hypothalamic regulation of body weight

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

Sch 50971, an orally active histamine H3 receptor agonist, inhibits central neurogenic vascular inflammation and produces sedation in the guinea pig.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

Behavioural characterization and amounts of brain monoamines and their metabolites in mice lacking histamine H1 receptors.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

Role of melanocortinergic neurons in feeding and the agouti obesity syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

Neuronal histamine in the hypothalamus suppresses food intake in rats

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

Inhibition of histamine synthesis in brain by alpha-fluoromethylhistidine, a new irreversible inhibitor: in vitro and in vivo studies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

Highly potent and selective ligands for histamine H3-receptors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

S-[2-(4-imidazolyl)ethyl]isothiourea, a highly specific and potent histamine H3 receptor agonist

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

Involvement of hypothalamic histamine H1 receptor in the regulation of feeding rhythm and obesity

8 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506104103

Effects of intracerebroventricularly infused histamine and selective H1, H2 and H3 agonists on food and water intake and urine flow in Wistar rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506104103

Central H3R activation by thioperamide does not affect energy balance

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506104103

Effect of alpha-fluoromethylhistidine on the histamine content of the brain of W/Wv mice devoid of mast cells: turnover of brain histamine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506104103

Activation of central melanocortin pathways by fenfluramine

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506104103

Cholecystokinin-mediated suppression of feeding involves the brainstem melanocortin system

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506104103

H3 agonist immepip markedly reduces cortical histamine release, but only weakly promotes sleep in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506104103

Simultaneous fluorometric measurement of histamine and tele-methylhistamine levels in rodent brain by high-performance liquid chromatography

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506104103

The role of central glucagon-like peptide-1 in mediating the effects of visceral illness: differential effects in rats and mice.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

Histamine H1 receptors mediate the anorectic action of the pancreatic hormone amylin

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560086

Abnormal temporal dynamics of visual attention in spatial neglect patients

25 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506104103

Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass

21 January 2018

1 reference

12 December 2020

Histamine turnover in regions of rat brain

1 reference

12 December 2020

Abnormalities in obese Zuckers: defective control of histaminergic functions

1 reference

12 December 2020

Sleep and waking during acute histamine H3 agonist BP 2.94 or H3 antagonist carboperamide (MR 16155) administration in rats

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0506104103

1 reference

5 August 2017

0 references

1 reference

5 August 2017

1 reference