(Q35022049)

5 August 2017

Inhibition of autoprocessing of natural variants and multidrug resistant mutant precursors of HIV-1 protease by clinical inhibitors (English)

1 reference

5 August 2017

multiple drug resistance

1 reference

3

Irene T Weber

1 reference

5 August 2017

John M Louis

1

1 reference

5 August 2017

Annie Aniana

series ordinal

2

1 reference

5 August 2017

Jane M Sayer

series ordinal

4

1 reference

5 August 2017

language of work or name

English

0 references

publication date

16 May 2011

1 reference

Proceedings of the National Academy of Sciences of the United States of America

5 August 2017

1 reference

5 August 2017

108

1 reference

5 August 2017

22

1 reference

5 August 2017

9072-9077

1 reference

In vitro selection of highly darunavir-resistant and replication-competent HIV-1 variants by using a mixture of clinical HIV-1 isolates resistant to multiple conventional protease inhibitors.

5 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107318

Autocatalytic maturation, physical/chemical properties, and crystal structure of group N HIV-1 protease: Relevance to drug resistance

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107318

Autoprocessing of human immunodeficiency virus type 1 protease miniprecursor fusions in mammalian cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107318

Update of the drug resistance mutations in HIV-1: December 2009.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107318

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107318

Interactions of different inhibitors with active-site aspartyl residues of HIV-1 protease and possible relevance to pepsin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107318

Visualizing transient events in amino-terminal autoprocessing of HIV-1 protease.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107318

Inhibition of HIV-2 protease by HIV-1 protease inhibitors in clinical use.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107318

Effect of the Active Site D25N Mutation on the Structure, Stability, and Ligand Binding of the Mature HIV-1 Protease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107318

Development of protease inhibitors and the fight with drug-resistant HIV-1 variants

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107318

HIV-1 protease: structure, dynamics, and inhibition

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107318

Structural and thermodynamic basis for the binding of TMC114, a next-generation human immunodeficiency virus type 1 protease inhibitor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107318

Initial cleavage of the human immunodeficiency virus type 1 GagPol precursor by its activated protease occurs by an intramolecular mechanism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107318

Intracellular and plasma pharmacokinetics of saquinavir-ritonavir, administered at 1,600/100 milligrams once daily in human immunodeficiency virus-infected patients

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107318

Phylogenetic characteristics of three new HIV-1 N strains and implications for the origin of group N.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107318

HIV-1 protease: maturation, enzyme specificity, and drug resistance.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107318

Three-dimensional solution structure of the HIV-1 protease complexed with DMP323, a novel cyclic urea-type inhibitor, determined by nuclear magnetic resonance spectroscopy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107318

Intracellular localization of human immunodeficiency virus type 1 Gag and GagPol products and virus particle release: relationship with the Gag-to-GagPol ratio

8 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1102278108

A major role for a set of non-active site mutations in the development of HIV-1 protease drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1102278108

Proteolytic processing of HIV-1 protease precursor, kinetics and mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1102278108

Binding kinetics of darunavir to human immunodeficiency virus type 1 protease explain the potent antiviral activity and high genetic barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1102278108

Identification of the minimal conserved structure of HIV-1 protease in the presence and absence of drug pressure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1102278108

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1102278108

Mutational and structural studies aimed at characterizing the monomer of HIV-1 protease and its precursor

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21576495

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Pharmacokinetics of darunavir/ritonavir and TMC125 alone and coadministered in HIV-negative volunteers

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21576495

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1102278108

1 reference

5 August 2017

0 references

1 reference

5 August 2017

1 reference