(Q35023017)

5 August 2017

title

Glucocorticoids suppress inflammation via the upregulation of negative regulator IRAK-M. (English)

1 reference

5 August 2017

0 references

Richard A Flavell

8

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author name string

Masanori Miyata

1

1 reference

5 August 2017

Ji-Yun Lee

2

1 reference

5 August 2017

Seiko Susuki-Miyata

3

1 reference

5 August 2017

Wenzhuo Y Wang

4

1 reference

5 August 2017

Haidong Xu

5

1 reference

5 August 2017

Hirofumi Kai

6

1 reference

5 August 2017

Koichi S Kobayashi

7

1 reference

5 August 2017

Jian-Dong Li

9

1 reference

5 August 2017

language of work or name

English

0 references

publication date

14 January 2015

1 reference

5 August 2017

published in

Nature Communications

1 reference

5 August 2017

volume

6

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5 August 2017

page(s)

6062

1 reference

Creative Commons Attribution 4.0 International

5 August 2017

copyright license

start time

14 January 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Inhibition of PDE4B suppresses inflammation by increasing expression of the deubiquitinase CYLD.

8 July 2018

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The five Rs of glucocorticoid action during inflammation: ready, reinforce, repress, resolve, and restore.

8 July 2018

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Insights into negative regulation by the glucocorticoid receptor from genome-wide profiling of inflammatory cistromes

8 July 2018

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Dissecting negative regulation of Toll-like receptor signaling

8 July 2018

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CYLD negatively regulates transforming growth factor-β-signalling via deubiquitinating Akt

8 July 2018

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Disease tolerance as a defense strategy

8 July 2018

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Chronic obstructive pulmonary disease

8 July 2018

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Maps and legends: the quest for dissociated ligands of the glucocorticoid receptor.

8 July 2018

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Coactivation of GR and NFKB alters the repertoire of their binding sites and target genes

8 July 2018

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Widespread negative response elements mediate direct repression by agonist-liganded glucocorticoid receptor

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

TGF-β-induced IRAK-M expression in tumor-associated macrophages regulates lung tumor growth

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

DAP12 promotes IRAK-M expression and IL-10 production by liver myeloid dendritic cells and restrains their T cell allostimulatory ability.

8 July 2018

1 reference

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COT drives resistance to RAF inhibition through MAP kinase pathway reactivation

8 July 2018

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IL-1 receptor-associated kinase M downregulates DSS-induced colitis

8 July 2018

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The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

8 July 2018

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Critical role of IL-1 receptor-associated kinase-M in regulating chemokine-dependent deleterious inflammation in murine influenza pneumonia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

Abrogation of glucocorticoid receptor dimerization correlates with dissociated glucocorticoid behavior of compound a.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

TREM-1 activation alters the dynamics of pulmonary IRAK-M expression in vivo and improves host defense during pneumococcal pneumonia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

Involvement of interleukin-1 receptor-associated kinase (IRAK)-M in toll-like receptor (TLR) 7-mediated tolerance in RAW 264.7 macrophage-like cells

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

Identification of potential pathway mediation targets in Toll-like receptor signaling

8 July 2018

1 reference

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Infection in the pathogenesis and course of chronic obstructive pulmonary disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

Pyogenic bacterial infections in humans with MyD88 deficiency

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

Induction of IRAK-M is associated with lipopolysaccharide tolerance in a human endotoxemia model

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

Nontypeable Haemophilus influenzae: understanding virulence and commensal behavior

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

IRAK-M is involved in the pathogenesis of early-onset persistent asthma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

Differential regulation and role of interleukin-1 receptor associated kinase-M in innate immunity signaling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

TGF-beta induces p65 acetylation to enhance bacteria-induced NF-kappaB activation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

Sepsis-induced suppression of lung innate immunity is mediated by IRAK-M.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

Conserved nontypeable Haemophilus influenzae-derived TLR2-binding lipopeptides synergize with IFN-beta to increase cytokine production by resident murine and human alveolar macrophages.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

A comprehensive map of the toll-like receptor signaling network

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

The tumor suppressor cylindromatosis (CYLD) acts as a negative regulator for toll-like receptor 2 signaling via negative cross-talk with TRAF6 AND TRAF7.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

The glucocorticoid receptor blocks P-TEFb recruitment by NFkappaB to effect promoter-specific transcriptional repression.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

IL-1 receptor-associated kinase M is a central regulator of osteoclast differentiation and activation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

Chromatin immunoprecipitation (ChIP) scanning identifies primary glucocorticoid receptor target genes.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

NF-kappaB is essential for induction of CYLD, the negative regulator of NF-kappaB: evidence for a novel inducible autoregulatory feedback pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

Synergistic activation of NF-kappaB by nontypeable Haemophilus influenzae and tumor necrosis factor alpha

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

Involvement of IRAK-M in peptidoglycan-induced tolerance in macrophages

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

Involvement of PTEN in airway hyperresponsiveness and inflammation in bronchial asthma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

Pyogenic bacterial infections in humans with IRAK-4 deficiency

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

IRAK-M is a negative regulator of Toll-like receptor signaling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

Activation of NF-kappa B by nontypeable Hemophilus influenzae is mediated by toll-like receptor 2-TAK1-dependent NIK-IKK alpha /beta-I kappa B alpha and MKK3/6-p38 MAP kinase signaling pathways in epithelial cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

The NF-kappa B and I kappa B proteins: new discoveries and insights

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

Interleukin 1 receptor-associated kinase m impairs host defense during pneumococcal pneumonia

8 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7062

The MyD88-dependent, but not the MyD88-independent, pathway of TLR4 signaling is important in clearing nontypeable haemophilus influenzae from the mouse lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7062

ChIP and Re-ChIP assays: investigating interactions between regulatory proteins, histone modifications, and the DNA sequences to which they bind.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7062

Genome-wide transcriptional profiling of mononuclear phagocytes recruited to mouse lungs in response to alveolar challenge with the TLR2 agonist Pam3CSK4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7062

Adiponectin promotes endotoxin tolerance in macrophages by inducing IRAK-M expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7062

Airway eosinophilia is not a requirement for allergen-induced airway hyperresponsiveness.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7062

Expression of pancreatic regenerating gene in lung and intestinal tissue correlates with the severity of disease in rats with acute necrotizing pancreatitis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309435

A novel role for the glucocorticoid receptor in the regulation of monocyte chemoattractant protein-1 mRNA stability

25 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25585690

12 December 2020

inferred from PubMed ID database lookup

Decreased mRNA stability as a mechanism of glucocorticoid-mediated inhibition of vascular endothelial growth factor gene expression by cultured keratinocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25585690

12 December 2020

inferred from PubMed ID database lookup

An official American Thoracic Society workshop report: features and measurements of experimental acute lung injury in animals

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25585690

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NCOMMS7062

1 reference

Dimensions Publication ID

5 August 2017

0 references

1038138800

0 references

Fatcat ID

release_ybrhomgv6nbjlf3qvygm3k3che

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ybrhomgv6nbjlf3qvygm3k3che

24 November 2022

mapped directly with Wikidata item

PMC publication ID

4309435

1 reference

5 August 2017

1 reference