(Q35031917)

5 August 2017

1 reference

title

Strategies for chemokine antagonists as therapeutics (English)

1 reference

5 August 2017

Timothy N C Wells

4

0 references

author name string

Amanda E I Proudfoot

series ordinal

1

1 reference

PubMed ID

12495641

5 August 2017

Christine A Power

series ordinal

2

1 reference

PubMed ID

12495641

5 August 2017

Christian Rommel

series ordinal

3

1 reference

5 August 2017

1 February 2003

1 reference

5 August 2017

Seminars in Immunology

1 reference

5 August 2017

15

1 reference

5 August 2017

1

1 reference

5 August 2017

57-65

1 reference

Purification of a human monocyte-derived neutrophil chemotactic factor that has peptide sequence similarity to other host defense cytokines

5 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

The human homolog of the JE gene encodes a monocyte secretory protein

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Resolution of the two components of macrophage inflammatory protein 1, and cloning and characterization of one of those components, macrophage inflammatory protein 1 beta

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Chemokines: a new classification system and their role in immunity

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Structure and Functional Expression of a Human Interleukin-8 Receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Cloning of complementary DNA encoding a functional human interleukin-8 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Identification of the discontinuous binding site in human interleukin 1 beta for the type I interleukin 1 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Is there a 'lock' for all agonist 'keys' in 7TM receptors?

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Chemokine receptors: multifaceted therapeutic targets

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Knock out models to dissect chemokine receptor function in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

A key role for CC chemokine receptor 4 in lipopolysaccharide-induced endotoxic shock

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

The murine CCR3 receptor regulates both the role of eosinophils and mast cells in allergen-induced airway inflammation and hyperresponsiveness

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Requirement for the chemokine receptor CCR6 in allergic pulmonary inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Aberrant in vivo T helper type 2 cell response and impaired eosinophil recruitment in CC chemokine receptor 8 knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Two-site binding of C5a by its receptor: an alternative binding paradigm for G protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Antagonists of monocyte chemoattractant protein 1 identified by modification of functionally critical NH2-terminal residues

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

A dominant negative inhibitor indicates that monocyte chemoattractant protein 1 functions as a dimer

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Extension of recombinant human RANTES by the retention of the initiating methionine produces a potent antagonist.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

New therapeutics that modulate chemokine networks

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Human interferon-inducible 10-kDa protein and human interferon-inducible T cell alpha chemoattractant are allotopic ligands for human CXCR3: differential binding to receptor states.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Species selectivity of a small molecule antagonist for the CCR1 chemokine receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Identification and characterization of a potent, selective, and orally active antagonist of the CC chemokine receptor-1

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

The coordinated action of CC chemokines in the lung orchestrates allergic inflammation and airway hyperresponsiveness

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

RANTES and monocyte chemoattractant protein-1 (MCP-1) play an important role in the inflammatory phase of crescentic nephritis, but only MCP-1 is involved in crescent formation and interstitial fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Targeting CCR2 or CD18 inhibits experimental in-stent restenosis in primates: inhibitory potential depends on type of injury and leukocytes targeted

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

An antagonist of monocyte chemoattractant protein 1 (MCP-1) inhibits arthritis in the MRL-lpr mouse model

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Effect of a CC chemokine receptor antagonist on collagen induced arthritis in DBA/1 mice

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

The chemokine RANTES is a crucial mediator of the progression from acute to chronic colitis in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Met-RANTES reduces vascular and tubular damage during acute renal transplant rejection: blocking monocyte arrest and recruitment

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Clinical effects of human macrophage inflammatory protein-1 alpha MIP-1α (LD78) administration to humans: a phase I study in cancer patients and normal healthy volunteers with the genetically engineered variant, BB-10010

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Differential binding of chemokines to glycosaminoglycan subpopulations

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Glycosaminoglycans interact selectively with chemokines and modulate receptor binding and cellular responses

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

The purified myxoma virus gamma interferon receptor homolog M-T7 interacts with the heparin-binding domains of chemokines

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

The viral anti-inflammatory chemokine-binding protein M-T7 reduces intimal hyperplasia after vascular injury

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Chemokine signalling: pivoting around multiple phosphoinositide 3-kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Lipids on the move: phosphoinositide 3-kinases in leukocyte function

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Vav2 is required for cell spreading

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Role of Rac in controlling the actin cytoskeleton and chemotaxis in motile cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Chemokine receptor homo- or heterodimerization activates distinct signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Rantes activates Jak2 and Jak3 to regulate engagement of multiple signaling pathways in T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Chemokine receptor dimerization: two are better than one.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Role of the C terminus of the interleukin 8 receptor in signal transduction and internalization

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: a novel inhibitory mechanism of HIV infectivity

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

CC chemokine receptor-3 undergoes prolonged ligand-induced internalization

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Aminooxypentane-RANTES induces CCR3 activation and internalization of CCR3 from the surface of human eosinophils

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2802%2900128-8

7 January 2021

10.1016/S1044-5323(02)00128-8

Identifiers

DOI

1 reference

5 August 2017

1 reference

PubMed ID

12495641