(Q35032772)

5 August 2017

title

Frequent genetic abnormalities of the PI3K/AKT pathway in primary ovarian cancer predict patient outcome (English)

1 reference

5 August 2017

1 reference

1 reference

Heini Lassus

8

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George Coukos

object named as

George Coukos

14

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Katherine L Nathanson

object named as

Katherine L Nathanson

12

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Dionyssios Katsaros

7

object named as

Dionyssios Katsaros

1 reference

5 August 2017

Jia Huang

1

1 reference

5 August 2017

Lin Zhang

2

1 reference

5 August 2017

Joel Greshock

3

1 reference

5 August 2017

Theresa A Colligon

4

1 reference

5 August 2017

Yan Wang

5

1 reference

5 August 2017

Renee Ward

6

1 reference

5 August 2017

Ralf Butzow

9

1 reference

5 August 2017

Andrew K Godwin

10

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5 August 2017

Joseph R Testa

11

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5 August 2017

Phyllis A Gimotty

13

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5 August 2017

Barbara L Weber

15

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5 August 2017

Yan Degenhardt

16

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5 August 2017

publication date

11 May 2011

1 reference

Genes, Chromosomes and Cancer

5 August 2017

published in

1 reference

5 August 2017

volume

50

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5 August 2017

issue

8

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5 August 2017

page(s)

606-618

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Identification of candidate growth promoting genes in ovarian cancer through integrated copy number and expression analysis

5 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

Mutations in the phosphatidylinositol-3-kinase pathway predict for antitumor activity of the inhibitor PX-866 whereas oncogenic Ras is a dominant predictor for resistance

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

Integrated genomic and transcriptional profiling identifies chromosomal loci with altered gene expression in cervical cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

Cancer cell lines as genetic models of their parent histology: analyses based on array comparative genomic hybridization

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

Promoting apoptosis as a strategy for cancer drug discovery

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

On the road to cancer: aneuploidy and the mitotic checkpoint

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

Array comparative genomic hybridization and its applications in cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

Role of transforming growth factor Beta in human cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

Origins and molecular pathology of ovarian cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

Wnt/beta-catenin signaling pathway as a novel cancer drug target

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

Targeting the mitogen-activated protein kinase cascade to treat cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

Role of STATs as downstream signal transducers in Src family kinase-mediated tumorigenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

Circular binary segmentation for the analysis of array-based DNA copy number data

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

Cancer genes and the pathways they control

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

p38 MAP kinase: a convergence point in cancer therapy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

High frequency of mutations of the PIK3CA gene in human cancers

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

Targeting PI3K-AKT pathway for cancer therapy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

1-Mb resolution array-based comparative genomic hybridization using a BAC clone set optimized for cancer gene analysis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

Oncogenic pathways implicated in ovarian epithelial cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

Role of Jun and Jun kinase in resistance of cancer cells to therapy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

Reduced expression of the murine p85alpha subunit of phosphoinositide 3-kinase improves insulin signaling and ameliorates diabetes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

The role of genetic abnormalities of PTEN and the phosphatidylinositol 3-kinase pathway in breast and ovarian tumorigenesis, prognosis, and therapy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

Analysis of gene expression profiles in normal and neoplastic ovarian tissue samples identifies candidate molecular markers of epithelial ovarian cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

Tissue microarrays for high-throughput molecular profiling of tumor specimens

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

PI3K: A rational target for ovarian cancer therapy?

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FGCC.20883

Chromosome 5 imbalance mapping in breast tumors from BRCA1 and BRCA2 mutation carriers and sporadic breast tumors.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FGCC.20883

RNA interference-mediated silencing of the phosphatidylinositol 3-kinase catalytic subunit attenuates growth of human ovarian cancer cells in vitroand in vivo

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FGCC.20883

Array-based comparative genomic hybridization for the differential diagnosis of renal cell cancer.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

The phosphatidylinositol 3'-kinase p85alpha gene is an oncogene in human ovarian and colon tumors.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110626

Distinct subtypes of serous ovarian carcinoma identified by p53 determination

25 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21563232

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Sequence mutations and amplification of PIK3CA and AKT2 genes in purified ovarian serous neoplasms

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21563232

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Integrative genomic analysis of phosphatidylinositol 3'-kinase family identifies PIK3R3 as a potential therapeutic target in epithelial ovarian cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21563232

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/GCC.20883

1 reference

5 August 2017

1 reference

5 August 2017

1 reference