(Q35177662)

6 August 2017

1 reference

title

Role of Jun and Jun kinase in resistance of cancer cells to therapy (English)

1 reference

6 August 2017

Irina Vasilevskaya

1

1 reference

PubMed ID

12860462

6 August 2017

Peter J O'Dwyer

series ordinal

2

1 reference

6 August 2017

1 June 2003

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6 August 2017

Drug Resistance Updates

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6 August 2017

6

1 reference

6 August 2017

147-156

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6 August 2017

3

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Mitogen-activated protein kinases

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Etoposide-induced activation of c-jun N-terminal kinase (JNK) correlates with drug-induced apoptosis in salivary gland acinar cells

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Direct activation of mitochondrial apoptosis machinery by c-Jun N-terminal kinase in adult cardiac myocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Enhanced ROS production in oncogenically transformed cells potentiates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase activation and sensitization to genotoxic stress

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Signaling pathways and effector mechanisms pre-programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

The role of MAPK pathways in the action of chemotherapeutic drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Molecular aspects of resistance to antitumor platinum drugs.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Jun NH2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Mammalian MAP kinase signalling cascades

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

ASK1 mediates apoptotic cell death induced by genotoxic stress.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Transcription factors as targets for cancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Signal transduction by the JNK group of MAP kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

JNK phosphorylation and activation of BAD couples the stress-activated signaling pathway to the cell death machinery

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

A novel AP-1 element in the CD95 ligand promoter is required for induction of apoptosis in hepatocellular carcinoma cells upon treatment with anticancer drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Role of mitogen-activated protein kinases in the response of tumor cells to chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Vinblastine-induced phosphorylation of Bcl-2 and Bcl-XL is mediated by JNK and occurs in parallel with inactivation of the Raf-1/MEK/ERK cascade

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Mixed-lineage kinase control of JNK and p38 MAPK pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Differential involvement of MEK kinase 1 (MEKK1) in the induction of apoptosis in response to microtubule-targeted drugs versus DNA damaging agents

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Inhibition of extracellular signal-regulated protein kinase or c-Jun N-terminal protein kinase cascade, differentially activated by cisplatin, sensitizes human ovarian cancer cell line

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

The activation of c-Jun NH2-terminal kinase (JNK) by DNA-damaging agents serves to promote drug resistance via activating transcription factor 2 (ATF2)-dependent enhanced DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

MAPK-regulated transcription: a continuously variable gene switch?

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Cellular stress response and apoptosis in cancer therapy.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

From receptors to stress-activated MAP kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Anti-apoptotic versus pro-apoptotic signal transduction: checkpoints and stop signs along the road to death.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

c-Jun can recruit JNK to phosphorylate dimerization partners via specific docking interactions

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Activation of MEK kinase 1 by the c-Abl protein tyrosine kinase in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Translocation of SAPK/JNK to mitochondria and interaction with Bcl-x(L) in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

The role of caspase-8 in resistance to cancer chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Prolonged Jun N-terminal kinase (JNK) activation and the upregulation of p53 and p21(WAF1/CIP1) preceded apoptosis in hepatocytes after partial hepatectomy and cisplatin

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

c-Jun-dependent CD95-L expression is a rate-limiting step in the induction of apoptosis by alkylating agents

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Variation in the kinetics of caspase-3 activation, Bcl-2 phosphorylation and apoptotic morphology in unselected human ovarian cancer cell lines as a response to docetaxel

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Paclitaxel (Taxol)-induced gene expression and cell death are both mediated by the activation of c-Jun NH2-terminal kinase (JNK/SAPK)

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

MEKK1 activates both IkappaB kinase alpha and IkappaB kinase beta

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Diverse functions of JNK signaling and c-Jun in stress response and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Regulation of platinum-compound cytotoxicity by the c-Jun N-terminal kinase and c-Jun signaling pathway in small-cell lung cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Cisplatin induction of ERCC-1 mRNA expression in A2780/CP70 human ovarian cancer cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Modulation of excision repair cross complementation group 1 (ERCC-1) mRNA expression by pharmacological agents in human ovarian carcinoma cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Integration of signals from receptor tyrosine kinases and g protein-coupled receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Regulation of c-Myc through phosphorylation at Ser-62 and Ser-71 by c-Jun N-terminal kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Nicotine affects the signaling of the death pathway, reducing the response of head and neck cancer cell lines to DNA damaging agents

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Reversal of cisplatin resistance in human ovarian cancer cell lines by a c-jun antisense oligodeoxynucleotide (ISIS 10582): evidence for the role of transcription factor overexpression in determining resistant phenotype

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Activation of c-Jun N-terminal kinase antagonizes an anti-apoptotic action of Bcl-2

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Rewiring MAP kinase pathways using alternative scaffold assembly mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

The Jun kinase/stress-activated protein kinase pathway functions to regulate DNA repair and inhibition of the pathway sensitizes tumor cells to cisplatin

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Protective role for c-Jun in the cellular response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Signal transduction. Imposing specificity on kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Lack of c-Jun activity increases survival to cisplatin

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Cisplatin induces a persistent activation of JNK that is related to cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

CL100/MKP-1 modulates JNK activation and apoptosis in response to cisplatin

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Cell stress and MEKK1-mediated c-Jun activation modulate NFkappaB activity and cell viability

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Cell signaling by receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

c-Jun NH2-terminal kinase-mediated activation of interleukin-1beta converting enzyme/CED-3-like protease during anticancer drug-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Differential regulation of mitogen-activated protein kinases by microtubule-binding agents in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Microtubule inhibitors elicit differential effects on MAP kinase (JNK, ERK, and p38) signaling pathways in human KB-3 carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Microtubule-interfering Agents Activate c-Jun N-terminal Kinase/Stress-activated Protein Kinase through Both Ras and Apoptosis Signal-regulating Kinase Pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Microtubule dysfunction induced by paclitaxel initiates apoptosis through both c-Jun N-terminal kinase (JNK)-dependent and -independent pathways in ovarian cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Paclitaxel-induced cell death: where the cell cycle and apoptosis come together

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Activation of the PI3K/Akt pathway and chemotherapeutic resistance

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

The JNK signal transduction pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

A mammalian scaffold complex that selectively mediates MAP kinase activation

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

The essential role of MEKK3 in TNF-induced NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

An anti-GD2 monoclonal antibody enhances apoptotic effects of anti-cancer drugs against small cell lung cancer cells via JNK (c-Jun terminal kinase) activation

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Tumor necrosis factor alpha gene regulation: enhancement of C/EBPbeta-induced activation by c-Jun

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Mitogen-activated protein kinase/ERK kinase kinases 2 and 3 activate nuclear factor-kappaB through IkappaB kinase-alpha and IkappaB kinase-beta

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

Components of a new human protein kinase signal transduction pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900043-8

7 January 2021

10.1016/S1368-7646(03)00043-8

Identifiers

DOI

1 reference

6 August 2017

1 reference

PubMed ID

12860462