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Toxin-induced mitochondrial dysfunction
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
12512343
retrieved
5 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
Toxin-induced mitochondrial dysfunction
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
12512343
retrieved
5 August 2017
author
M. Flint Beal
series ordinal
2
object named as
M Flint Beal
1 reference
stated in
Europe PubMed Central
PubMed ID
12512343
retrieved
5 August 2017
author name string
Susan E Browne
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
12512343
retrieved
5 August 2017
publication date
1 January 2002
1 reference
stated in
Europe PubMed Central
PubMed ID
12512343
retrieved
5 August 2017
published in
International Review of Neurobiology
1 reference
stated in
Europe PubMed Central
PubMed ID
12512343
retrieved
5 August 2017
volume
53
1 reference
stated in
Europe PubMed Central
PubMed ID
12512343
retrieved
5 August 2017
page(s)
243-279
1 reference
stated in
Europe PubMed Central
PubMed ID
12512343
retrieved
5 August 2017
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Coenzyme Q10 and nicotinamide block striatal lesions produced by the mitochondrial toxin malonate
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Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease
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Acetyl-levo-carnitine protects against MPTP-induced parkinsonism in primates.
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Decreases in mouse brain NAD+ and ATP induced by 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP): prevention by the poly(ADP-ribose) polymerase inhibitor, benzamide.
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Effect of intranigral Mn2+ on striatal and nigral synthesis and levels of dopamine and cofactor.
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7 January 2021
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Uptake and release of manganese by rat striatal slices
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Crossref
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7 January 2021
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7 January 2021
based on heuristic
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7 January 2021
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Neurological conditions resulting from prolonged and severe dietary restriction; case reports in prisoners-of-war, and general review
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Crossref
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7 January 2021
based on heuristic
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Effects of 3-acetylpyridine on the central nervous system of the rat, as demonstrated by silver methods.
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Crossref
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7 January 2021
based on heuristic
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Correlation between 1-methyl-4-phenylpyridinium ion (MPP+) levels, ascorbic acid oxidation and glutathione levels in the striatal synaptosomes of the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated rat
1 reference
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7 January 2021
based on heuristic
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Role of oxidative stress in the manganese and 1-methyl-4-(2'-ethylphenyl)-1,2,3,6-tetrahydropyridine-induced apoptosis in PC12 cells
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based on heuristic
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3-Acetylpyridine-induced degeneration of the nigrostriatal dopamine system: an animal model of olivopontocerebellar atrophy-associated parkinsonism
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based on heuristic
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1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and 1-methyl-4-phenylpyridine (MPP+) cause rapid ATP depletion in isolated hepatocytes
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Crossref
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Involvement of a caspase-3-like cysteine protease in 1-methyl-4-phenylpyridinium-mediated apoptosis of cultured cerebellar granule neurons.
1 reference
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Ubiquinone (coenzyme q10) and mitochondria in oxidative stress of parkinson's disease
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7 January 2021
based on heuristic
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Protection by synergistic effects of adenovirus-mediated X-chromosome-linked inhibitor of apoptosis and glial cell line-derived neurotrophic factor gene transfer in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.
1 reference
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7 January 2021
based on heuristic
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Salicylate protects against MPTP-induced impairments in dopaminergic neurotransmission at the striatal and nigral level in mice
1 reference
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Crossref
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7 January 2021
based on heuristic
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Systemic administration of rotenone produces selective damage in the striatum and globus pallidus, but not in the substantia nigra.
1 reference
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7 January 2021
based on heuristic
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Neuroprotective effects of creatine in a transgenic mouse model of Huntington's disease.
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7 January 2021
based on heuristic
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Locus ceruleus lesions and eosinophilic inclusions in MPTP-treated monkeys.
1 reference
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7 January 2021
based on heuristic
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Erythropoietin exerts neuroprotection in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated C57/BL mice via increasing nitric oxide production
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7 January 2021
based on heuristic
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Animal models of Parkinson's disease: an empirical comparison with the phenomenology of the disease in man.
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7 January 2021
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Manganese superoxide dismutase protects nNOS neurons from NMDA and nitric oxide-mediated neurotoxicity.
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Crossref
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7 January 2021
based on heuristic
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Protein nitration in Parkinson's disease.
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7 January 2021
based on heuristic
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The risk of Parkinson's disease with exposure to pesticides, farming, well water, and rural living
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7 January 2021
based on heuristic
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Basal ganglia degeneration, myelin alterations, and enzyme inhibition induced in mice by the plant toxin 3-nitropropanoic acid
1 reference
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7 January 2021
based on heuristic
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Brain enzyme and clinical alterations induced in rats and mice by nitroaliphatic toxicants.
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7 January 2021
based on heuristic
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Mitochondrial defect in Huntington's disease caudate nucleus
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7 January 2021
based on heuristic
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Parkinsonism, pyramidal signs, polyneuropathy, and cognitive decline after long-term occupational solvent exposure.
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7 January 2021
based on heuristic
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Nature and distribution of brain lesions in rats intoxicated with 3-nitropropionic acid: a type of hypoxic (energy deficient) brain damage.
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7 January 2021
based on heuristic
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Inhibition of neuronal nitric oxide synthase prevents MPTP-induced parkinsonism in baboons.
1 reference
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7 January 2021
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Epidemiological study of lathyrism in northwestern districts of Bangladesh.
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7 January 2021
based on heuristic
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Delayed dystonia with striatal CT lucencies induced by a mycotoxin (3-nitropropionic acid)
1 reference
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Crossref
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7 January 2021
based on heuristic
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Dopaminergic toxicity of rotenone and the 1-methyl-4-phenylpyridinium ion after their stereotaxic administration to rats: implication for the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity.
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of alpha-phenyl-N-tert-butyl nitrone and alternative electron acceptors with complex I indicates a substrate reduction site upstream from the rotenone binding site.
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
[3H]dihydrorotenone binding to NADH: ubiquinone reductase (complex I) of the electron transport chain: an autoradiographic study.
1 reference
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https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Manganese mimics the action of 1-methyl-4-phenylpyridinium ion, a dopaminergic neurotoxin, in rat striatal tissue slices
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
alpha-synuclein promotes mitochondrial deficit and oxidative stress
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Chronic carbon disulfide encephalopathy.
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Long-term progression in chronic manganism: ten years of follow-up
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial encephalomyopathy (MELAS): pathological study and successful therapy with coenzyme Q10 and idebenone
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Intense immunoreactivity for Mn-superoxide dismutase (Mn-SOD) in cholinergic and non-cholinergic neurons in the rat basal forebrain
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Selective accumulation of MPP+ in the substantia nigra: a key to neurotoxicity?
1 reference
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Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
1-methyl-4-phenyl-pyridinium ion (MPP+) causes DNA fragmentation and increases the Bcl-2 expression in human neuroblastoma, SH-SY5Y cells, through different mechanisms
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for impairment of energy metabolism in vivo in Huntington's disease using localized 1H NMR spectroscopy
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Protective effects of the antiparkinsonian drugs talipexole and pramipexole against 1-methyl-4-phenylpyridinium-induced apoptotic death in human neuroblastoma SH-SY5Y cells.
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Manganese superoxide dismutase overexpression attenuates MPTP toxicity.
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mice deficient in group IV cytosolic phospholipase A2 are resistant to MPTP neurotoxicity.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of neuronal nitric oxide synthase protects against MPTP toxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Energy metabolism defects in Huntington's disease and effects of coenzyme Q10.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The influence of acidosis on hypoglycemic brain damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Excitotoxins L-beta-oxalyl-amino-alanine (L-BOAA) and 3,4,6-trihydroxyphenylalanine (6-OH-DOPA) inhibit [3H] alpha-amino-3- hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) binding in human hippocampus.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The inflammatory reaction following 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine intoxication in mouse.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of the overexpression of wild-type or mutant alpha-synuclein on cell susceptibility to insult
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rat striatal dopamine and tetrahydrobiopterin content following an intrastriatal injection of manganese chloride.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antioxidant treatment improves in vivo cardiac and skeletal muscle bioenergetics in patients with Friedreich's ataxia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Noninfectious environmental agents associated with myopathies.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Levodopa failure in chronic manganism.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
3-Nitropropionic acid-exogenous animal neurotoxin and possible human striatal toxin.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuroprotective effects of creatine administration against NMDA and malonate toxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Brain, skeletal muscle and platelet homogenate mitochondrial function in Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MPP+ induced substantia nigra degeneration is attenuated in nNOS knockout mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuroprotective effects of creatine and cyclocreatine in animal models of Huntington's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Novel free radical spin traps protect against malonate and MPTP neurotoxicity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isoquinoline derivatives as endogenous neurotoxins in the aetiology of Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Valproate treatment induces lipid globule accumulation with ultrastructural abnormalities of mitochondria in skeletal muscle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Parkinson's disease, pesticides, and glutathione transferase polymorphisms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Experimental striatal necrosis induced by sodium azide. A contribution to the problem of selective vulnerability and histochemical studies of enzymatic activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deficiencies in complex I subunits of the respiratory chain in Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis is induced by 1-methyl-4-phenylpyridinium ion (MPP+) in ventral mesencephalic-striatal co-culture in rat.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuroprotection by sodium salicylate against 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-induced neurotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The antioxidant ebselen prevents neurotoxicity and clinical symptoms in a primate model of Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuroprotection by bromocriptine against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Levels of 5-hydroxytryptamine, dopamine and norepinephrine in whole brain of rabbits in chronic manganese toxicity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
1-Methyl-4-phenylpyridinum kills differentiated PC12 cells with a concomitant change in protein phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective depletion of caudate nucleus dopamine and serotonin during chronic manganese dioxide administration to squirrel monkeys.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Visualizing manganese in the primate basal ganglia with magnetic resonance imaging
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell death induced by MPTP, a substrate for monoamine oxidase B.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energy levels are reduced
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of Bcl-2 attenuates MPP+, but not 6-ODHA, induced cell death in a dopaminergic neuronal cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Etiology and pathogenesis of Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Manganese intoxication in the rhesus monkey: a clinical, imaging, pathologic, and biochemical study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
L-BOAA induces selective inhibition of brain mitochondrial enzyme, NADH-dehydrogenase.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abnormalities of the electron transport chain in idiopathic Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lack of muscle toxicity with didanosine (ddI). Clinical and experimental studies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mass spectrometric quantification of 3-nitrotyrosine, ortho-tyrosine, and o,o'-dityrosine in brain tissue of 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-treated mice, a model of oxidative stress in Parkinson's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
EXPERIMENTAL MANGANESE ENCEPHALOPATHY IN MONKEYS. A PRELIMINARY REPORT
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxidative post-translational modifications of alpha-synuclein in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurological sequelae of cyanide intoxication--the patterns of clinical, magnetic resonance imaging, and positron emission tomography findings.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific antagonism of behavioral action of "uncommon" amino acids linked to motor-system diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and free radicals in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MPTP activates c-Jun NH(2)-terminal kinase (JNK) and its upstream regulatory kinase MKK4 in nigrostriatal neurons in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biochemical mechanism of action of the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial complex I deficiency in Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
3-Acetylpyridine produces age-dependent excitotoxic lesions in rat striatum.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Coenzyme Q10 and nicotinamide and a free radical spin trap protect against MPTP neurotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP-induced neurotoxicity in mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of free radicals in excitotoxicity in vivo.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuroprotective strategies for treatment of lesions produced by mitochondrial toxins: implications for neurodegenerative diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of oxidative stress in 3-nitropropionic acid neurotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuroprotective effects of the pyrrolopyrimidine U-104067F in 3-acetylpyridine-treated rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuroprotective effects of the GABA(A) receptor partial agonist U-101017 in 3-acetylpyridine-treated rats.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuroprotective effects of the dopamine agonists pramipexole and bromocriptine in 3-acetylpyridine-treated rats.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of 1-methyl-4-phenylpyridinium on glutathione in rat pheochromocytoma PC 12 cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MPP+ induced apoptotic cell death in SH-SY5Y neuroblastoma cells: an electron microscope study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chronic reduction in complex I function alters calcium signaling in SH-SY5Y neuroblastoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Electron microscope study of the rat brain with experimental sodium azide intoxication
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Coenzyme Q10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective lesions by manganese and extensive damage by iron after injection into rat striatum or hippocampus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Occupational fatality and persistent neurological sequelae after mass exposure to hydrogen sulfide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MPP+ inhibits proliferation of PC12 cells by a p21(WAF1/Cip1)-dependent pathway and induces cell death in cells lacking p21(WAF1/Cip1)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lathyrism: evidence for role of the neuroexcitatory aminoacid BOAA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Guam amyotrophic lateral sclerosis-parkinsonism-dementia linked to a plant excitant neurotoxin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Manganese augments nitric oxide synthesis in murine astrocytes: a new pathogenetic mechanism in manganism?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thiol oxidation and loss of mitochondrial complex I precede excitatory amino acid-mediated neurodegeneration.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HEK-293 cells expressing the human dopamine transporter are susceptible to low concentrations of 1-methyl-4-phenylpyridine (MPP+) via impairment of energy metabolism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Matrilineal inheritance of complex I dysfunction in a multigenerational Parkinson's disease family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of acute and repeated treatment with a novel dopamine D2 receptor ligand on L-DOPA-induced dyskinesias in MPTP monkeys
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
3-Acetylpyridine neurotoxicity to the nigrostriatal dopamine system in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased caspase 3 and Bax immunoreactivity accompany nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of the cyclooxygenase isoenzymes COX-1 and COX-2 provide neuroprotection in the MPTP-mouse model of Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endogenous dopaminergic tone and dopamine agonist action
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dopamine neurons from transgenic mice with a knockout of the p53 gene resist MPTP neurotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Brain damage caused by hydrogen sulfide: a follow-up study of six patients.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyanide-induced parkinsonism: a clinicopathologic report.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chronic MPTP treatment reproduces in baboons the differential vulnerability of mesencephalic dopaminergic neurons observed in Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CGP 3466 protects dopaminergic neurons in lesion models of Parkinson's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Niacinamide blocks 3-acetylpyridine toxicity of cerebellar granule cells in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Destruction of the nucleus raphe obscurus and potentiation of serotonin-mediated behaviors following administration of the neurotoxin 3-acetylpyridine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuronal damage induced by beta-N-oxalylamino-L-alanine, in the rat hippocampus, can be prevented by a non-NMDA antagonist, 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuroprotective effect of free radical scavengers on beta-N-oxalylamino-L-alanine (BOAA)-induced neuronal damage in rat hippocampus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Positron emission tomography in manganese intoxication
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
3‐Nitropropionic Acid Toxicity in the Striatum
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glutathione depletion potentiates MPTP and MPP+ toxicity in nigral dopaminergic neurones.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chronic manganese poisoning: a neuropathological study with determination of manganese distribution in the brain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyride neurotoxicity is attenuated in mice overexpressing Bcl-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nitric oxide in retina: relation to excitatory amino acids and excitotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Manganese inhibits mitochondrial aconitase: a mechanism of manganese neurotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pramipexole inhibits lipid peroxidation and reduces injury in the substantia nigra induced by the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in C57BL/6 mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Partial inhibition of brain succinate dehydrogenase by 3-nitropropionic acid is sufficient to initiate striatal degeneration in rat.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2953010-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0074-7742(02)53010-5
1 reference
stated in
Europe PubMed Central
PubMed ID
12512343
retrieved
5 August 2017
PubMed ID
12512343
1 reference
stated in
Europe PubMed Central
PubMed ID
12512343
retrieved
5 August 2017
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