(Q35040955)

6 August 2017

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title

Is there a unifying mechanism for protein folding? (English)

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6 August 2017

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2

Alan R Fersht

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6 August 2017

1

Valerie Daggett

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6 August 2017

1 January 2003

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6 August 2017

8

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Trends in Biochemical Sciences

inferred from page(s)

published in

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6 August 2017

28

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6 August 2017

1

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6 August 2017

18-25

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Nucleation, rapid folding, and globular intrachain regions in proteins

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Specific intermediates in the folding reactions of small proteins and the mechanism of protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

A model of myoglobin self-organization

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Intermediates in the folding reactions of small proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Protein-folding dynamics

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Some factors in the interpretation of protein denaturation

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

How does protein folding get started?

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Helix-coil transition of the isolated amino terminus of ribonuclease

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

A salt bridge stabilizes the helix formed by isolated C-peptide of RNase A

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Nature of the charged-group effect on the stability of the C-peptide helix

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

The influence of long-range interactions on the structure of myoglobin

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Folding of a nascent polypeptide chain in vitro: cooperative formation of structure in a protein module.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Structures of folding intermediates

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

The denatured state (the other half of the folding equation) and its role in protein stability.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

The chicken-egg scenario of protein folding revisited

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Folding of chymotrypsin inhibitor 2. 1. Evidence for a two-state transition

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Structure of the transition state for the folding/unfolding of the barley chymotrypsin inhibitor 2 and its implications for mechanisms of protein folding.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

The Structure of the Transition State for Folding of Chymotrypsin Inhibitor 2 Analysed by Protein Engineering Methods: Evidence for a Nucleation-condensation Mechanism for Protein Folding

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Optimization of rates of protein folding: the nucleation-condensation mechanism and its implications

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Nucleation mechanisms in protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Molecular dynamics simulations of the protein unfolding/folding reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Specific nucleus as the transition state for protein folding: evidence from the lattice model.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Multiple protein folding nuclei and the transition state ensemble in two-state proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Protein folding funnels: the nature of the transition state ensemble

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Topological and energetic factors: what determines the structural details of the transition state ensemble and "en-route" intermediates for protein folding? An investigation for small globular proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Structural correlations in protein folding funnels

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Exploring structures in protein folding funnels with free energy functionals: the transition state ensemble

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Protein folding and unfolding at atomic resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Protein folding from a highly disordered denatured state: the folding pathway of chymotrypsin inhibitor 2 at atomic resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Characterization of the transition state of protein unfolding by use of molecular dynamics: chymotrypsin inhibitor 2

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Structure of the transition state for folding of a protein derived from experiment and simulation.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Identification and characterization of the unfolding transition state of chymotrypsin inhibitor 2 by molecular dynamics simulations.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Protein folding and unfolding in microseconds to nanoseconds by experiment and simulation

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

A comparison of the pH, urea, and temperature-denatured states of barnase by heteronuclear NMR: implications for the initiation of protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Characterization of residual structure in the thermally denatured state of barnase by simulation and experiment: description of the folding pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Towards a complete description of the structural and dynamic properties of the denatured state of barnase and the role of residual structure in folding

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Molecular dynamics simulation of the unfolding of barnase: characterization of the major intermediate.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

The folding of an enzyme. IV. Structure of an intermediate in the refolding of barnase analysed by a protein engineering procedure

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

The folding of an enzyme. III. Structure of the transition state for unfolding of barnase analysed by a protein engineering procedure

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Cracking the folding code. Why do some proteins adopt partially folded conformations, whereas other don't?

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Preorganized secondary structure as an important determinant of fast protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Folding and stability of a fibronectin type III domain of human tenascin

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Mapping the interactions present in the transition state for unfolding/folding of FKBP12.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Fast and slow tracks in lysozyme folding: insight into the role of domains in the folding process

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Direct observation of better hydration at the N terminus of an alpha-helix with glycine rather than alanine as the N-cap residue

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Increasing temperature accelerates protein unfolding without changing the pathway of unfolding.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Determination of the three-dimensional solution structure of barnase using nuclear magnetic resonance spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

Structural studies of the engrailed homeodomain

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2900012-9

7 January 2021

10.1016/S0968-0004(02)00012-9

Identifiers

DOI

1 reference

6 August 2017

1 reference

PubMed ID

12517448