(Q35042726)

6 August 2017

title

High-content assays for hepatotoxicity using induced pluripotent stem cell-derived cells (English)

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6 August 2017

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Oksana Sirenko

1

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6 August 2017

Jayne Hesley

series ordinal

2

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6 August 2017

Ivan Rusyn

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3

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6 August 2017

Evan F Cromwell

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4

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6 August 2017

publication date

14 November 2013

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Assay and Drug Development Technologies

6 August 2017

published in

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6 August 2017

volume

12

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6 August 2017

issue

1

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6 August 2017

page(s)

43-54

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describes a project that uses

6 August 2017

induced pluripotent stem cell

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Developing high-fidelity hepatotoxicity models from pluripotent stem cells

inferred from title

cites work

1 reference

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Comparison of electrophysiological data from human-induced pluripotent stem cell-derived cardiomyocytes to functional preclinical safety assays

8 July 2018

1 reference

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In vitro models for liver toxicity testing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934660

The effects of jaspamide on human cardiomyocyte function and cardiac ion channel activity

8 July 2018

1 reference

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Assessment of an automated in vitro basal cytotoxicity test system based on metabolically-competent cells

8 July 2018

1 reference

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ToxPi GUI: an interactive visualization tool for transparent integration of data from diverse sources of evidence

8 July 2018

1 reference

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Current challenges and controversies in drug-induced liver injury.

8 July 2018

1 reference

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Mechanisms of zolpidem-induced long QT syndrome: acute inhibition of recombinant hERG K(+) channels and action potential prolongation in human cardiomyocytes derived from induced pluripotent stem cells

8 July 2018

1 reference

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HER2-targeted liposomal doxorubicin displays enhanced anti-tumorigenic effects without associated cardiotoxicity

8 July 2018

1 reference

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Drug-induced liver injury: a summary of recent advances.

8 July 2018

1 reference

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Chemically defined conditions for human iPSC derivation and culture

8 July 2018

1 reference

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Opportunities for use of human iPS cells in predictive toxicology

8 July 2018

1 reference

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Gene expression analysis of precision-cut human liver slices indicates stable expression of ADME-Tox related genes.

8 July 2018

1 reference

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Efficient generation of transgene-free induced pluripotent stem cells from normal and neoplastic bone marrow and cord blood mononuclear cells

8 July 2018

1 reference

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New directions in toxicity testing

8 July 2018

1 reference

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Toxicology for the twenty-first century

8 July 2018

1 reference

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A toxicology for the 21st century--mapping the road ahead

8 July 2018

1 reference

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Mechanisms of drug-induced liver disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934660

Three distinct stages of apoptotic nuclear condensation revealed by time-lapse imaging, biochemical and electron microscopy analysis of cell-free apoptosis

8 July 2018

1 reference

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High concordance of drug-induced human hepatotoxicity with in vitro cytotoxicity measured in a novel cell-based model using high content screening

8 July 2018

1 reference

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Can the pharmaceutical industry reduce attrition rates?

8 July 2018

1 reference

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Acute Liver Failure in the United States

8 July 2018

1 reference

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Drug-induced hepatotoxicity.

8 July 2018

1 reference

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In vitro models to study hepatotoxicity.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934660

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934660

Are in vitro tests suitable for regulatory use?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934660

High-content screening: a decade of evolution

25 October 2018

1 reference

12 December 2020

The Use of Hepatocytes to Investigate Drug Toxicity

1 reference

12 December 2020

Characterization of human-induced pluripotent stem cell-derived cardiomyocytes: bioenergetics and utilization in safety screening

1 reference

12 December 2020

The liver slice system: An in vitro acute toxicity test for assessment of hepatotoxins and their antidotes

1 reference

12 December 2020

Identifiers

DOI

10.1089/ADT.2013.520

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6 August 2017

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6 August 2017

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