(Q35070899)

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Constitutive ALK5-independent c-Jun N-terminal kinase activation contributes to endothelin-1 overexpression in pulmonary fibrosis: evidence of an autocrine endothelin loop operating through the endothelin A and B receptors

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scholarly article

1 reference

Europe PubMed Central

6 August 2017

Constitutive ALK5-independent c-Jun N-terminal kinase activation contributes to endothelin-1 overexpression in pulmonary fibrosis: evidence of an autocrine endothelin loop operating through the endothelin A and B receptors (English)

1 reference

Europe PubMed Central

6 August 2017

pulmonary fibrosis

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

3

object named as

Santiago Lamas

1 reference

Europe PubMed Central

6 August 2017

author name string

Xu Shi-Wen

1

1 reference

Europe PubMed Central

6 August 2017

Fernando Rodríguez-Pascual

2

1 reference

Europe PubMed Central

6 August 2017

Alan Holmes

4

1 reference

Europe PubMed Central

6 August 2017

Sarah Howat

5

1 reference

Europe PubMed Central

6 August 2017

Jeremy D Pearson

6

1 reference

Europe PubMed Central

6 August 2017

Michael R Dashwood

7

1 reference

Europe PubMed Central

6 August 2017

Roland M du Bois

8

1 reference

Europe PubMed Central

6 August 2017

Christopher P Denton

9

1 reference

Europe PubMed Central

6 August 2017

Carol M Black

10

1 reference

Europe PubMed Central

6 August 2017

David J Abraham

11

1 reference

Europe PubMed Central

6 August 2017

Andrew Leask

12

1 reference

Europe PubMed Central

6 August 2017

language of work or name

0 references

publication date

1 July 2006

1 reference

Europe PubMed Central

6 August 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

6 August 2017

26

1 reference

Europe PubMed Central

6 August 2017

5518-5527

1 reference

Europe PubMed Central

6 August 2017

14

1 reference

Europe PubMed Central

6 August 2017

Matrix contraction by dermal fibroblasts requires transforming growth factor-beta/activin-linked kinase 5, heparan sulfate-containing proteoglycans, and MEK/ERK: insights into pathological scarring in chronic fibrotic disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

CCN2 (connective tissue growth factor) promotes fibroblast adhesion to fibronectin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Targeted disruption of TGF-beta/Smad3 signaling modulates skin fibrosis in a mouse model of scleroderma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

TGF-beta signaling and the fibrotic response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/Akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic fibroblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Endothelin-1 induces expression of matrix-associated genes in lung fibroblasts through MEK/ERK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Impaired Smad7-Smurf-mediated negative regulation of TGF-beta signaling in scleroderma fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Cell and molecular regulation of endothelin-1 production during hepatic wound healing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Pulmonary fibrosis: cellular and molecular events

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Connective tissue growth factor gene regulation. Requirements for its induction by transforming growth factor-beta 2 in fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

The comparative role of activator protein 1 and Smad factors in the regulation of Timp-1 and MMP-1 gene expression by transforming growth factor-beta 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

The JNK-interacting protein-1 scaffold protein targets MAPK phosphatase-7 to dephosphorylate JNK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

A central role for the JNK pathway in mediating the antagonistic activity of pro-inflammatory cytokines against transforming growth factor-beta-driven SMAD3/4-specific gene expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

The extracellular matrix as a scaffold for tissue reconstruction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

CTGF expression in mesangial cells: involvement of SMADs, MAP kinase, and PKC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Myofibroblasts and mechano-regulation of connective tissue remodelling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Transforming growth factor-beta and connective tissue growth factor: key cytokines in scleroderma pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Smad3/AP-1 interactions control transcriptional responses to TGF-beta in a promoter-specific manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Localisation of transforming growth factor beta1 and beta3 mRNA transcripts in normal and fibrotic human lung

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Fibroblast matrix gene expression and connective tissue remodeling: role of endothelin-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

A cytokine reborn? Endothelin-1 in pulmonary inflammation and fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Tumor necrosis factor alpha suppresses the induction of connective tissue growth factor by transforming growth factor-beta in normal and scleroderma fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Role and interaction of connective tissue growth factor with transforming growth factor-beta in persistent fibrosis: A mouse fibrosis model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Induction of subcutaneous tissue fibrosis in newborn mice by transforming growth factor beta--simultaneous application with basic fibroblast growth factor causes persistent fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Increased levels of endothelin-1 and differential endothelin type A and B receptor expression in scleroderma-associated fibrotic lung disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Pathogenesis of scleroderma. Collagen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Cell-specific induction of distinct oncogenes of the Jun family is responsible for differential regulation of collagenase gene expression by transforming growth factor-beta in fibroblasts and keratinocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Molecular pharmacology of endothelin converting enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Impaired regulation of collagen pro-alpha 1(I) mRNA and change in pattern of collagen-binding integrins on scleroderma fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Stable expression of a c-JUN deletion mutant in two malignant mouse epidermal cell lines blocks tumor formation in nude mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Mechanism of action of a dominant-negative mutant of c-Jun.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Fibroblasts, myofibroblasts, and wound contraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Increased endothelin-1 production in fibroblasts derived from patients with systemic sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Factors influencing myofibroblast differentiation during wound healing and fibrosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Role of connective tissue proteases in the pathogenesis of chronic inflammatory lung disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Clinical deterioration in patients with idiopathic pulmonary fibrosis: causes and assessment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Interleukin 1 (IL-1) gene expression, synthesis, and effect of specific IL-1 receptor blockade in rabbit immune complex colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Collagen synthesis and degradation by systemic sclerosis lung fibroblasts. Responses to transforming growth factor-beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Spontaneous Activation of Transforming Growth Factor-β Gene Transcription in Broncho-Alveolar Mononuclear Cells of Individuals with Systemic Autoimmune Diseases with Lung Involvement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Production of a tissue-like structure by contraction of collagen lattices by human fibroblasts of different proliferative potential in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

8 July 2018

Prostacyclin derivatives prevent the fibrotic response to TGF-beta by inhibiting the Ras/MEK/ERK pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

27 September 2018

Functional characterization of transforming growth factor beta signaling in Smad2- and Smad3-deficient fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

27 September 2018

CTGF and SMADs, maintenance of scleroderma phenotype is independent of SMAD signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592704

27 September 2018

Transforming growth Factor-beta1 induces phenotypic modulation of human lung fibroblasts to myofibroblast through a c-Jun-NH2-terminal kinase-dependent pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/16809784

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of activin receptor-like kinase 5 (transforming growth factor beta receptor type I) signaling to the fibrotic phenotype of scleroderma fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/16809784

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional cooperation between Smad proteins and activator protein-1 regulates transforming growth factor-beta-mediated induction of endothelin-1 expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/16809784

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and regulation of intracellular SMAD signaling in scleroderma skin fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/16809784

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissecting the roles of endothelin, TGF-beta and GM-CSF on myofibroblast differentiation by keratinocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16809784

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/16809784

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding characteristics and vascular effects of various angiotensin II antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/16809784

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/16809784

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Significance of plasma endothelin-1 levels in patients with systemic sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16809784

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterization of a phosphoramidon-sensitive endothelin-converting enzyme in porcine aortic endothelium. OFF

1 reference

https://pubmed.ncbi.nlm.nih.gov/16809784

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated levels of platelet derived growth factor and transforming growth factor-beta 1 in bronchoalveolar lavage fluid from patients with scleroderma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16809784

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Scleroderma lung fibroblasts exhibit elevated and dysregulated type I collagen biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16809784

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective tyrosine kinase inhibitor for the platelet-derived growth factor receptor in vitro inhibits smooth muscle cell proliferation after reinjury of arterial intima in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/16809784

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.00625-06

1 reference

Europe PubMed Central

6 August 2017

release_ognrrjmafrd3lnfmd7srypf7xq

1 reference

https://api.fatcat.wiki/v0/release/ognrrjmafrd3lnfmd7srypf7xq

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

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