(Q35082073)

6 August 2017

title

Saturation transfer difference NMR for fragment screening (English)

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6 August 2017

Darren W Begley

1

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6 August 2017

Spencer O Moen

series ordinal

2

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6 August 2017

Phillip G Pierce

series ordinal

3

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6 August 2017

Edward R Zartler

series ordinal

4

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6 August 2017

publication date

1 January 2013

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Current protocols in chemical biology

6 August 2017

published in

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6 August 2017

volume

5

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6 August 2017

issue

4

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6 August 2017

page(s)

251-268

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Ligand efficiency indices as guideposts for drug discovery.

6 August 2017

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Interactions between the human sweet-sensing T1R2-T1R3 receptor and sweeteners detected by saturation transfer difference NMR spectroscopy

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New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays

21 January 2018

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Lessons for fragment library design: analysis of output from multiple screening campaigns

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A fragment-based approach for the discovery of isoform-specific p38alpha inhibitors

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From fragment to clinical candidate--a historical perspective.

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A ‘Rule of Three’ for fragment-based lead discovery?

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A Small-Molecule Probe Induces a Conformation in HIV TAR RNA Capable of Binding Drug-Like Fragments

21 January 2018

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Discovery of Leukotriene A4 Hydrolase Inhibitors Using Metabolomics Biased Fragment Crystallography †

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Screening protein-small molecule interactions by NMR.

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Learning from our mistakes: the 'unknown knowns' in fragment screening

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Transforming fragments into candidates: small becomes big in medicinal chemistry

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Quest for the rings. In silico exploration of ring universe to identify novel bioactive heteroaromatic scaffolds

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21 January 2018

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21 January 2018

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

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NMR-based characterization of phenothiazines as a RNA binding scaffold

21 January 2018

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Group epitope mapping by saturation transfer difference NMR to identify segments of a ligand in direct contact with a protein receptor

21 January 2018

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21 January 2018

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21 January 2018

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Sugar-oligoamides: bound-state conformation and DNA minor-groove-binding description by TR-NOESY and differential-frequency saturation-transfer-difference experiments

21 January 2018

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HTS by NMR of combinatorial libraries: a fragment-based approach to ligand discovery

21 January 2018

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The effect of relaxation on the epitope mapping by saturation transfer difference NMR.

21 January 2018

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Fragonomics: fragment-based drug discovery

21 January 2018

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ID NMR Methods in ligand-receptor interactions

21 January 2018

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Screening nucleotide binding to amino acid-coated supports by surface plasmon resonance and nuclear magnetic resonance

21 January 2018

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10.1002/9780470559277.CH130118

21 January 2018

Identifiers

DOI

1 reference

6 August 2017

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