(Q35976375)

11 August 2017

1 reference

title

NMR-based techniques in the hit identification and optimisation processes (English)

1 reference

11 August 2017

Barbara Becattini

2

0 references

Martino Forino

object named as

Martino Forino

5

0 references

Roberto Fattorusso

object named as

Roberto Fattorusso

4

0 references

Marco Fragai

object named as

Marco Fragai

6

0 references

author name string

Maurizio Pellecchia

1

1 reference

11 August 2017

Kevin J Crowell

3

1 reference

11 August 2017

Dawoon Jung

7

1 reference

11 August 2017

Tomas Mustelin

8

1 reference

11 August 2017

Lutz Tautz

9

1 reference

11 August 2017

language of work or name

English

0 references

publication date

1 December 2004

1 reference

Expert Opinion on Therapeutic Targets

11 August 2017

1 reference

11 August 2017

8

1 reference

11 August 2017

6

1 reference

11 August 2017

597-611

1 reference

11 August 2017

NMR in drug discovery

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

Application of NMR screening in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

NMR-based screening method for transglutaminases: rapid analysis of their substrate specificities and reaction rates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

NMR spectroscopy techniques for screening and identifying ligand binding to protein receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

NMR methods for the determination of protein-ligand dissociation constants

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

Fluorine nuclear magnetic resonance of fluorinated ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

Aurintricarboxylic acid blocks in vitro and in vivo activity of YopH, an essential virulent factor of Yersinia pestis, the agent of plague.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

Glucose transporter of Escherichia coli: NMR characterization of the phosphocysteine form of the IIB(Glc) domain and its binding interface with the IIA(Glc) subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

The catalytic mechanism of Cdc25A phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

Use of selective Trp side chain labeling to characterize protein-protein and protein-ligand interactions by NMR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

Identification of compounds with binding affinity to proteins via magnetization transfer from bulk water.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

High-throughput NMR-based screening with competition binding experiments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

Caspases: preparation and characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

Reliable high-throughput functional screening with 3-FABS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

A Strategy for High-Throughput Assay Development Using Leads Derived from Nuclear Magnetic Resonance-Based Screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

The SHAPES strategy: an NMR-based approach for lead generation in drug discovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

Discovering high-affinity ligands for proteins: SAR by NMR

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

Second-site NMR screening and linker design

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

Targeting apoptosis via chemical design: inhibition of bid-induced cell death by small organic molecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

Property distribution of drug-related chemical databases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

The properties of known drugs. 1. Molecular frameworks

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

Development and validation of a genetic algorithm for flexible docking

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

A geometric approach to macromolecule-ligand interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

A fast flexible docking method using an incremental construction algorithm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

LigandFit: a novel method for the shape-directed rapid docking of ligands to protein active sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

Consensus scoring for ligand/protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

Evaluation of the FLEXX incremental construction algorithm for protein-ligand docking

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

Discovery and Structure−Activity Relationship of Oxalylarylaminobenzoic Acids as Inhibitors of Protein Tyrosine Phosphatase 1B

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

NMR-based screening in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

Novel inhibitors of Erm methyltransferases from NMR and parallel synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

IAP family proteins--suppressors of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

Fragment-based lead discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

WaterLOGSY as a method for primary NMR screening: practical aspects and range of applicability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.6.597

21 January 2018

Identifiers

DOI

10.1517/14728222.8.6.597

1 reference

11 August 2017

1 reference