(Q35091480)

6 August 2017

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title

Viral versus cellular BCL-2 proteins (English)

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6 August 2017

Hardwick JM

1

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PubMed ID

12655348

6 August 2017

Bellows DS

series ordinal

2

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6 August 2017

1 January 2003

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Cell Death & Differentiation

6 August 2017

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6 August 2017

10 Suppl 1

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6 August 2017

S68-76

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401133

6 August 2017

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cites work

Inhibition of virus-induced neuronal apoptosis by Bax.

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Conversion of Bcl-2 to a Bax-like death effector by caspases

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Modulation of cell death by Bcl-XL through caspase interaction

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Solution structure of a Bcl-2 homolog from Kaposi sarcoma virus

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Breaking the mitochondrial barrier

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

The Bcl-2 protein family: arbiters of cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Epstein-Barr virus BHRF1 protein protects against cell death induced by DNA-damaging agents and heterologous viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

The effect of Epstein-Barr virus gene BHRF1 expression on radioresistance of nasopharyngeal carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Overexpression of the human BCL-2 gene product results in growth enhancement of Epstein-Barr virus-immortalized B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

DNA rearrangements in human follicular lymphoma can involve the 5' or the 3' region of the bcl-2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Mechanism of paclitaxel activity in Kaposi's sarcoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Antisense to the Epstein-Barr virus (EBV)-encoded latent membrane protein 1 (LMP-1) sensitizes EBV-immortalized B cells to transforming growth factor-beta and chemotherapeutic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Epstein-Barr virus BALF1 is a BCL-2-like antagonist of the herpesvirus antiapoptotic BCL-2 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Bax-independent inhibition of apoptosis by Bcl-XL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

The biochemistry of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Tumor necrosis factor-alpha induces Bax-Bak interaction and apoptosis, which is inhibited by adenovirus E1B 19K

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Viral homologs of BCL-2: role of apoptosis in the regulation of virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Epstein-Barr virus-coded BHRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Herpesvirus papio encodes a functional homologue of the Epstein-Barr virus apoptosis suppressor, BHRF1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

BHRF1 is highly conserved in primate virus analogues of Epstein-Barr virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

A Bcl-2 homolog encoded by Kaposi sarcoma-associated virus, human herpesvirus 8, inhibits apoptosis but does not heterodimerize with Bax or Bak

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Antiapoptotic herpesvirus Bcl-2 homologs escape caspase-mediated conversion to proapoptotic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Structure of Bax: coregulation of dimer formation and intracellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Alphaviruses induce apoptosis in Bcl-2-overexpressing cells: evidence for a caspase-mediated, proteolytic inactivation of Bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Cleavage of Bax enhances its cell death function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Granzyme B induces BID-mediated cytochrome c release and mitochondrial permeability transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Caspase cleavage enhances the apoptosis-inducing effects of BAD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

The apoptotic v-cyclin-CDK6 complex phosphorylates and inactivates Bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Aven, a novel inhibitor of caspase activation, binds Bcl-xL and Apaf-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

The cellular protein PRA1 modulates the anti-apoptotic activity of Epstein-Barr virus BHRF1, a homologue of Bcl-2, through direct interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Diva, a Bcl-2 homologue that binds directly to Apaf-1 and induces BH3-independent cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Bok is a pro-apoptotic Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with selective anti-apoptotic Bcl-2 family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

A splicing variant of the Bcl-2 member Bok with a truncated BH3 domain induces apoptosis but does not dimerize with antiapoptotic Bcl-2 proteins in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Induction of Bad-mediated apoptosis by Sindbis virus infection: involvement of pro-survival members of the Bcl-2 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

A novel function for SMN, the spinal muscular atrophy disease gene product, in pre-mRNA splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Movement of Bax from the cytosol to mitochondria during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Degenerative disorders caused by Bcl-2 deficiency prevented by loss of its BH3-only antagonist Bim

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

The changing landscape of ischaemic brain injury mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Dimerization properties of human BAD. Identification of a BH-3 domain and analysis of its binding to mutant BCL-2 and BCL-XL proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Cell permeable BH3-peptides overcome the cytoprotective effect of Bcl-2 and Bcl-X(L).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Growth factors can influence cell growth and survival through effects on glucose metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Biology of Kaposi's sarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

HIV protease inhibitors are potent anti-angiogenic molecules and promote regression of Kaposi sarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Epidemiology and pathogenesis of Kaposi's sarcoma-associated herpesvirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Epidemiological evidence for causal relationship between Epstein-Barr virus and Burkitt's lymphoma from Ugandan prospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Biology and disease associations of Epstein-Barr virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Distinct interactions of the X-linked lymphoproliferative syndrome gene product SAP with cytoplasmic domains of members of the CD2 receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Regulation of SLAM-mediated signal transduction by SAP, the X-linked lymphoproliferative gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

LMP1 structure and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Molecular virology of Epstein-Barr virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Deregulation of cell growth by the K1 gene of Kaposi's sarcoma-associated herpesvirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Molecular piracy of Kaposi's sarcoma associated herpesvirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Characterization of an anti-apoptotic glycoprotein encoded by Kaposi's sarcoma-associated herpesvirus which resembles a spliced variant of human survivin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

The 19-Kilodalton Adenovirus E1B Transforming Protein Inhibits Programmed Cell Death and Prevents Cytolysis by Tumor Necrosis Factor α

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

BHRF1, a viral homologue of the Bcl-2 oncogene, is conserved at both the sequence and functional level in different Epstein-Barr virus isolates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Complex transcription of the Epstein-Barr virus BamHI fragment H rightward open reading frame 1 (BHRF1) in latently and lytically infected B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Epstein-Barr virus mRNAs produced by alternative splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Identification of an Epstein-Barr virus early gene encoding a second component of the restricted early antigen complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Identification of the in vivo role of a viral bcl-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

A prospective study in heart and lung transplant recipients correlating persistent Epstein-Barr virus infection with clinical events

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Kaposi's sarcoma-associated herpesvirus encodes a functional Bcl-2 homologue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

Epstein-Barr virus BHRF1 protein protects intestine 407 epithelial cells from apoptosis induced by tumor necrosis factor alpha and anti-Fas antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

7 January 2021

Suppression of c-Myc-induced apoptosis by the Epstein-Barr virus gene product BHRF1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

7 January 2021

Viral interference with apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

7 January 2021

Involvement of the bcl-2 gene in human follicular lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

7 January 2021

Epstein-Barr virus encodes a novel homolog of the bcl-2 oncogene that inhibits apoptosis and associates with Bax and Bak.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

7 January 2021

The murine gammaherpesvirus-68 M11 protein inhibits Fas- and TNF-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

7 January 2021

Herpesvirus saimiri encodes a functional homolog of the human bcl-2 oncogene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

7 January 2021

A new Epstein-Barr virus transactivator, R, induces expression of a cytoplasmic early antigen

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

7 January 2021

Acceleration of apoptotic cell death after the cleavage of Bcl-XL protein by caspase-3-like proteases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

7 January 2021

Caspase-3-dependent cleavage of Bcl-2 promotes release of cytochrome c

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

7 January 2021

Pro-apoptotic cleavage products of Bcl-xL form cytochrome c-conducting pores in pure lipid membranes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

7 January 2021

All along the watchtower: on the regulation of apoptosis regulators.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

7 January 2021

Nonionic detergents induce dimerization among members of the Bcl-2 family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

7 January 2021

Bcl-xL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

7 January 2021

Novel hypotheses for the roles of EBNA-1 and BHRF1 in EBV-related cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

7 January 2021

Three distinct regions of the murine gammaherpesvirus 68 genome are transcriptionally active in latently infected mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401133

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401133

1 reference

6 August 2017

1 reference

PubMed ID

12655348