(Q35095308)

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PIK3CA mutations frequently coexist with EGFR/KRAS mutations in non-small cell lung cancer and suggest poor prognosis in EGFR/KRAS wildtype subgroup

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scholarly article

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Europe PubMed Central

PubMed publication ID

6 August 2017

PIK3CA mutations frequently coexist with EGFR/KRAS mutations in non-small cell lung cancer and suggest poor prognosis in EGFR/KRAS wildtype subgroup (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

non-small-cell lung carcinoma

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based on heuristic

inferred from title

object named as

Yongfu Yu

7

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author name string

Lei Wang

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Haichuan Hu

2

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Europe PubMed Central

PubMed publication ID

6 August 2017

Yunjian Pan

3

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Rui Wang

4

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Yuan Li

5

1 reference

Europe PubMed Central

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6 August 2017

Lei Shen

6

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Hang Li

8

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Deng Cai

9

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Yihua Sun

10

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Europe PubMed Central

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6 August 2017

Haiquan Chen

11

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6 August 2017

language of work or name

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publication date

12 February 2014

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Europe PubMed Central

PubMed publication ID

6 August 2017

1 reference

Europe PubMed Central

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6 August 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

e88291

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

copyright license

Creative Commons Attribution 4.0 International

12 February 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

PIK3CA mutations in advanced cancers: characteristics and outcomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

9 July 2018

Phosphoinositide 3-kinase (PI3K) pathway alterations are associated with histologic subtypes and are predictive of sensitivity to PI3K inhibitors in lung cancer preclinical models.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

9 July 2018

PI3K expression and PIK3CA mutations are related to colorectal cancer metastases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

9 July 2018

Spectrum of oncogenic driver mutations in lung adenocarcinomas from East Asian never smokers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

9 July 2018

Coexistence of PIK3CA and other oncogene mutations in lung adenocarcinoma-rationale for comprehensive mutation profiling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

9 July 2018

Highly frequent promoter methylation and PIK3CA amplification in non-small cell lung cancer (NSCLC).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

9 July 2018

International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

9 July 2018

Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

9 July 2018

Lung adenocarcinoma from East Asian never-smokers is a disease largely defined by targetable oncogenic mutant kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

9 July 2018

Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

9 July 2018

Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

9 July 2018

Phosphatidylinositol-3-kinase and AKT1 mutations occur early in breast carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

9 July 2018

KIF5B-ALK, a novel fusion oncokinase identified by an immunohistochemistry-based diagnostic system for ALK-positive lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

9 July 2018

PIK3CA mutations and copy number gains in human lung cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

9 July 2018

Phosphatidylinositol 3-kinase in breast cancer: where from here?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

9 July 2018

Activation of the mTOR signaling pathway in breast cancer and its correlation with the clinicopathologic variables

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

9 July 2018

PIK3CA mutation and amplification in human lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

9 July 2018

Allelic dilution obscures detection of a biologically significant resistance mutation in EGFR-amplified lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

9 July 2018

The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

9 July 2018

Phosphoinositide 3-kinase: from viral oncoprotein to drug target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

9 July 2018

Oncogenic PI3K and its role in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

9 July 2018

Inhibition of mammalian target of rapamycin reverses alveolar epithelial neoplasia induced by oncogenic K-ras

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

9 July 2018

PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

9 July 2018

The biology and clinical relevance of the PTEN tumor suppressor pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

9 July 2018

High frequency of mutations of the PIK3CA gene in human cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

9 July 2018

Loss of PTEN expression as a prognostic marker for tongue cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

9 July 2018

KRAS mutation in patients with lung cancer: a predictor for poor prognosis but not for EGFR-TKIs or chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

27 September 2018

Expression of p-AKT and p-mTOR in a large series of bronchopulmonary neuroendocrine tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

27 September 2018

PIK3CA overexpression is a possible prognostic factor for favorable survival in ovarian clear cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

27 September 2018

Somatic mutation analysis of EGFR, KRAS, BRAF and PIK3CA in 861 patients with non-small cell lung cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

27 September 2018

A novel KIF5B-ALK variant in nonsmall cell lung cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

27 September 2018

Frequent PIK3CA gene amplification and its clinical significance in colorectal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

27 September 2018

A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

27 September 2018

Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: a cohort study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

27 September 2018

PI3K-AKT pathway mediates growth and survival signals during development of fetal mouse lung

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

27 September 2018

Frequent activation of AKT in non-small cell lung carcinomas and preneoplastic bronchial lesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

27 September 2018

PIK3CA is implicated as an oncogene in ovarian cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3922761

27 September 2018

Biomarker Analyses and Final Overall Survival Results From a Phase III, Randomized, Open-Label, First-Line Study of Gefitinib Versus Carboplatin/Paclitaxel in Clinically Selected Patients With Advanced Non–Small-Cell Lung Cancer in Asia (IPASS)

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0088291

21 January 2018

PTEN expression in non–small-cell lung cancer: evaluating its relation to tumor characteristics, allelic loss, and epigenetic alteration

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0088291

21 January 2018

PIK3CA mutation status in Japanese lung cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/24533074

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different prognostic roles of mutations in the helical and kinase domains of the PIK3CA gene in breast carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/24533074

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein expression and prognostic value of genes in the erb-b signaling pathway in advanced ovarian carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/24533074

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early involvement of the phosphatidylinositol 3-kinase/Akt pathway in lung cancer progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/24533074

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and prognostic significance of PTEN product protein in patients with esophageal squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/24533074

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PONE.0088291

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

2014PLoSO...988291W

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release_lhqwrn2brrdxhnv4blt5fqvr2a

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https://api.fatcat.wiki/v0/release/lhqwrn2brrdxhnv4blt5fqvr2a

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

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Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

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Europe PubMed Central

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6 August 2017

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