(Q35106192)

6 August 2017

1 reference

title

The role of SHIP in cytokine-induced signaling (English)

1 reference

6 August 2017

2

L. M. Sly

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12692707

23 December 2023

3

M. R. Hughes

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12692707

23 December 2023

author name string

L-P Cao

6

1 reference

6 August 2017

J. Kalesnikoff

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12692707

23 December 2023

T. Büchse

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12692707

23 December 2023

M. J. Rauh

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12692707

23 December 2023

V. Lam

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12692707

23 December 2023

A. Mui

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12692707

23 December 2023

M. Huber

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12692707

23 December 2023

G. Krystal

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12692707

23 December 2023

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12692707

23 December 2023

publication date

12 April 2003

1 reference

full work available at URL

6 August 2017

http://www.springerlink.com/index/pdf/10.1007/s10254-003-0016-y

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Reviews of Physiology, Biochemistry and Pharmacology

23 December 2023

published in

1 reference

6 August 2017

149

1 reference

6 August 2017

87-103

1 reference

https://scigraph.springernature.com/pub.10.1007/s10254-003-0016-y

6 August 2017

0 references

cites work

Essential role for the C-terminal noncatalytic region of SHIP in FcgammaRIIB1-mediated inhibitory signaling

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Negative feedback regulation of the tumor suppressor PTEN by phosphoinositide-induced serine phosphorylation

23 December 2023

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Effects of overexpression of the SH2-containing inositol phosphatase SHIP on proliferation and apoptosis of erythroid AS-E2 cells

23 December 2023

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1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

SHIP modulates immune receptor responses by regulating membrane association of Btk.

23 December 2023

4

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Shc associates with the IL-3 receptor β subunit, SHIP and Gab2 following IL-3 stimulation

23 December 2023

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1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Bilevel control of B-cell activation by the inositol 5-phosphatase SHIP.

23 December 2023

6

1 reference

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Partially distinct molecular mechanisms mediate inhibitory FcgammaRIIB signaling in resting and activated B cells

23 December 2023

7

1 reference

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The two SH2-domain-containing inositol 5-phosphatases SHIP1 and SHIP2 are coexpressed in human T lymphocytes

23 December 2023

8

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

23 December 2023

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Regulation of protein kinase C zeta by PI 3-kinase and PDK-1

23 December 2023

10

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The lipid phosphatase SHIP2 controls insulin sensitivity

23 December 2023

11

1 reference

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Inhibitory signaling by B cell Fc gamma RIIb

23 December 2023

12

1 reference

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Death receptors bind SHP-1 and block cytokine-induced anti-apoptotic signaling in neutrophils

23 December 2023

13

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase

23 December 2023

14

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

SHIP's C-terminus is essential for its hydrolysis of PIP3 and inhibition of mast cell degranulation

23 December 2023

16

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Dissecting the thrombopoietin receptor: functional elements of the Mpl cytoplasmic domain

23 December 2023

18

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

The phosphatidylinositol polyphosphate 5-phosphatase SHIP1 associates with the dok1 phosphoprotein in bcr-Abl transformed cells

23 December 2023

19

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin

23 December 2023

20

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Disruption of a single Pten allele augments the chemotactic response of B lymphocytes to stromal cell-derived factor-1.

23 December 2023

22

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Positive regulation of interleukin-4-mediated proliferation by the SH2-containing inositol-5'-phosphatase

23 December 2023

25

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Tyrosine phosphorylation and relocation of SHIP are integrin-mediated in thrombin-stimulated human blood platelets

23 December 2023

26

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

The src homology domain 2-containing inositol phosphatase SHIP forms a ternary complex with Shc and Grb2 in antigen receptor-stimulated B lymphocytes

23 December 2023

27

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Targeted disruption of SHIP leads to hemopoietic perturbations, lung pathology, and a shortened life span

23 December 2023

28

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Genomewide search in familial Paget disease of bone shows evidence of genetic heterogeneity with candidate loci on chromosomes 2q36, 10p13, and 5q35

23 December 2023

29

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Association of SH2-containing inositol phosphatase 2 with the insulin resistance of diabetic db/db mice

23 December 2023

30

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

The inositol 5-phosphatase SHIP is expressed as 145 and 135 kDa proteins in blood and bone marrow cells in vivo, whereas carboxyl-truncated forms of SHIP are generated by proteolytic cleavage in vitro.

23 December 2023

31

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Targeted disruption of SHIP leads to Steel factor-induced degranulation of mast cells.

23 December 2023

32

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

The src homology 2-containing inositol phosphatase (SHIP) is the gatekeeper of mast cell degranulation

23 December 2023

33

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

The role of SHIP in growth factor induced signalling.

23 December 2023

34

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Vav3 modulates B cell receptor responses by regulating phosphoinositide 3-kinase activation

23 December 2023

38

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Molecular cloning of rat SH2-containing inositol phosphatase 2 (SHIP2) and its role in the regulation of insulin signaling

23 December 2023

39

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

PDGF induces an early and a late wave of PI 3-kinase activity, and only the late wave is required for progression through G1.

23 December 2023

41

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

SHIP represses mast cell activation and reveals that IgE alone triggers signaling pathways which enhance normal mast cell survival

23 December 2023

42

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

SHIP negatively regulates IgE + antigen-induced IL-6 production in mast cells by inhibiting NF-kappa B activity

23 December 2023

43

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Immunoreceptor tyrosine-based inhibitory motif of the IL-4 receptor associates with SH2-containing phosphatases and regulates IL-4-induced proliferation

23 December 2023

44

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Multiple forms of an inositol polyphosphate 5-phosphatase form signaling complexes with Shc and Grb2

23 December 2023

45

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Altered responsiveness to chemokines due to targeted disruption of SHIP.

23 December 2023

46

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

The negative signaling molecule SH2 domain-containing inositol-polyphosphate 5-phosphatase (SHIP) binds to the tyrosine-phosphorylated beta subunit of the high affinity IgE receptor

23 December 2023

47

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Co-clustering of Fcgamma and B cell receptors induces dephosphorylation of the Grb2-associated binder 1 docking protein

23 December 2023

48

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Lipid phosphatases in the immune system

23 December 2023

49

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Shc interaction with Src homology 2 domain containing inositol phosphatase (SHIP) in vivo requires the Shc-phosphotyrosine binding domain and two specific phosphotyrosines on SHIP

23 December 2023

50

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Protein kinase C-delta is a negative regulator of antigen-induced mast cell degranulation

23 December 2023

52

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Dok-3, a novel adapter molecule involved in the negative regulation of immunoreceptor signaling

23 December 2023

53

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

p150Ship, a signal transduction molecule with inositol polyphosphate-5-phosphatase activity

23 December 2023

54

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Multiple cytokines stimulate the binding of a common 145-kilodalton protein to Shc at the Grb2 recognition site of Shc

23 December 2023

55

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

The Src homology 2 (SH2) domain of SH2-containing inositol phosphatase (SHIP) is essential for tyrosine phosphorylation of SHIP, its association with Shc, and its induction of apoptosis

23 December 2023

56

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Interleukin-3 induces the association of the inositol 5-phosphatase SHIP with SHP2

23 December 2023

57

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

SHIP is a negative regulator of growth factor receptor-mediated PKB/Akt activation and myeloid cell survival

23 December 2023

59

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Scaffolding protein Gab2 mediates differentiation signaling downstream of Fms receptor tyrosine kinase

23 December 2023

60

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

23 December 2023

62

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

SHC and SHIP phosphorylation and interaction in response to activation of the FLT3 receptor

23 December 2023

63

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

TAPP1 and TAPP2 are targets of phosphatidylinositol 3-kinase signaling in B cells: sustained plasma membrane recruitment triggered by the B-cell antigen receptor

23 December 2023

64

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Interleukin-10 and the interleukin-10 receptor

23 December 2023

67

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Inactivating mutations in an SH2 domain-encoding gene in X-linked lymphoproliferative syndrome

23 December 2023

69

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Stat3-dependent induction of p19INK4D by IL-10 contributes to inhibition of macrophage proliferation.

23 December 2023

70

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor Fc(gamma)RIIB.

23 December 2023

71

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Deletion of SHIP or SHP-1 reveals two distinct pathways for inhibitory signaling

23 December 2023

72

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

The inositol 5'-phosphatase SHIP binds to immunoreceptor signaling motifs and responds to high affinity IgE receptor aggregation

23 December 2023

73

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Downstream of kinase, p62(dok), is a mediator of Fc gamma IIB inhibition of Fc epsilon RI signaling

23 December 2023

74

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Identification of a second SH2-domain-containing protein closely related to the phosphatidylinositol polyphosphate 5-phosphatase SHIP

23 December 2023

75

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

The SH2 domain containing inositol 5-phosphatase SHIP2 displays phosphatidylinositol 3,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate 5-phosphatase activity

23 December 2023

76

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Enzymatic activity of the Src homology 2 domain-containing inositol phosphatase is regulated by a plasma membrane location

23 December 2023

77

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

The role of phosphoinositide 3-kinase lipid products in cell function

23 December 2023

78

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

The phosphatidylinositol polyphosphate 5-phosphatase SHIP and the protein tyrosine phosphatase SHP-2 form a complex in hematopoietic cells which can be regulated by BCR/ABL and growth factors

23 December 2023

80

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

SHIP1, an SH2 domain containing polyinositol-5-phosphatase, regulates migration through two critical tyrosine residues and forms a novel signaling complex with DOK1 and CRKL

23 December 2023

81

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM

23 December 2023

82

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

PtdIns-3,4,5-P3: a regulatory nexus between tyrosine kinases and sustained calcium signals.

23 December 2023

83

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Phosphatidylinositol (3,4,5)P3 is essential but not sufficient for protein kinase B (PKB) activation; phosphatidylinositol (3,4)P2 is required for PKB phosphorylation at Ser-473: studies using cells from SH2-containing inositol-5-phosphatase knockou

23 December 2023

84

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

CD150 association with either the SH2-containing inositol phosphatase or the SH2-containing protein tyrosine phosphatase is regulated by the adaptor protein SH2D1A

23 December 2023

85

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

SHIP-mediated inhibition of K562 erythroid differentiation requires an intact catalytic domain and Shc binding site

23 December 2023

86

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

23 December 2023

87

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts

23 December 2023

88

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

The RasGAP-binding protein p62dok is a mediator of inhibitory FcgammaRIIB signals in B cells

23 December 2023

89

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Recruitment and phosphorylation of SH2-containing inositol phosphatase and Shc to the B-cell Fc gamma immunoreceptor tyrosine-based inhibition motif peptide motif

23 December 2023

90

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Src Homology 2 Domain-Containing Inositol Polyphosphate Phosphatase Regulates NF- B-Mediated Gene Transcription by Phagocytic Fc Rs in Human Myeloid Cells

23 December 2023

92

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Embryonic and hematopoietic stem cells express a novel SH2-containing inositol 5'-phosphatase isoform that partners with the Grb2 adapter protein

23 December 2023

93

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Activin/TGF-beta induce apoptosis through Smad-dependent expression of the lipid phosphatase SHIP.

23 December 2023

94

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Differential association of phosphatases with hematopoietic co-receptors bearing immunoreceptor tyrosine-based inhibition motifs

23 December 2023

97

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Erythropoietin induces the tyrosine phosphorylation of insulin receptor substrate-2. An alternate pathway for erythropoietin-induced phosphatidylinositol 3-kinase activation

23 December 2023

98

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

Cloning of the genomic locus of mouse SH2 containing inositol 5-phosphatase (SHIP) and a novel 110-kDa splice isoform, SHIPdelta

23 December 2023

101

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

SH2 domain-containing inositol polyphosphate 5'-phosphatase is the main mediator of the inhibitory action of the mast cell function-associated antigen

23 December 2023

102

1 reference

https://api.crossref.org/works/10.1007/S10254-003-0016-Y

23 December 2023

Identifiers

0 references

1 reference