(Q35107526)

6 August 2017

Mitochondrion-dependent N-terminal processing of outer membrane Mcl-1 protein removes an essential Mule/Lasu1 protein-binding site (English)

1 reference

Maureen D O'Connor-McCourt

6 August 2017

1 reference

10

object named as

Maureen O'Connor-McCourt

1 reference

6 August 2017

Matthew R Warr

1

1 reference

6 August 2017

John R Mills

2

1 reference

6 August 2017

Mai Nguyen

3

1 reference

6 August 2017

Stephanie Lemaire-Ewing

4

1 reference

6 August 2017

Jason Baardsnes

5

1 reference

6 August 2017

Karen L W Sun

6

1 reference

6 August 2017

Abba Malina

7

1 reference

6 August 2017

Jason C Young

8

1 reference

6 August 2017

Danny V Jeyaraju

9

1 reference

6 August 2017

Luca Pellegrini

11

1 reference

6 August 2017

Jerry Pelletier

12

1 reference

6 August 2017

Gordon C Shore

13

1 reference

6 August 2017

language of work or name

English

0 references

publication date

25 May 2011

1 reference

6 August 2017

10

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

1 reference

6 August 2017

286

1 reference

6 August 2017

28

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6 August 2017

25098-25107

1 reference

describes a project that uses

6 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3137083/fullTextXML

inferred from PubMed Central ID database lookup

cites work

SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

Heterodimerization of BAK and MCL-1 activated by detergent micelles

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

The fast-mobility isoform of mouse Mcl-1 is a mitochondrial matrix-localized protein with attenuated anti-apoptotic activity

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

Ubiquitin-independent degradation of antiapoptotic MCL-1.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

The landscape of somatic copy-number alteration across human cancers

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

mTORC1 promotes survival through translational control of Mcl-1.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

Unique biology of Mcl-1: therapeutic opportunities in cancer

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

The BCL-2 protein family: opposing activities that mediate cell death

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

N-terminal truncation of antiapoptotic MCL1, but not G2/M-induced phosphorylation, is associated with stabilization and abundant expression in tumor cells.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

Degradation of Mcl-1 by beta-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

Translocation of proteins into mitochondria

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

An internal EELD domain facilitates mitochondrial targeting of Mcl-1 via a Tom70-dependent pathway

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

Mcl-1 overexpression in hepatocellular carcinoma: a potential target for antisense therapy

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

BH3-ligand regulates access of MCL-1 to its E3 ligase

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

MCL-1 expression in B-cell non-Hodgkin's lymphomas

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

During apoptosis bcl-2 changes membrane topology at both the endoplasmic reticulum and mitochondria

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

Cell death: critical control points

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

Regulation of apoptosis by endoplasmic reticulum pathways.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

MCL1 provides a window on the role of the BCL2 family in cell proliferation, differentiation and tumorigenesis

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

Mcl-1 deficiency results in peri-implantation embryonic lethality

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

Regulated targeting of BAX to mitochondria.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells.

9 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M111.218321

Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M111.218321

Expression of apoptosis-regulating proteins in chronic lymphocytic leukemia: correlations with In vitro and In vivo chemoresponses.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137083

Expression of apoptotic regulators and their significance in cervical cancer

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21613222

12 December 2020

inferred from PubMed ID database lookup

Immunohistochemical analysis of Bcl-2, Bax, Bcl-X, and Mcl-1 expression in pancreatic cancers

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21613222

12 December 2020

inferred from PubMed ID database lookup

Unraveling MCL-1 degradation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21613222

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1074/JBC.M111.218321

1 reference

release_ldfmcoxn2nd3hpmej7n5biy3ja

6 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ldfmcoxn2nd3hpmej7n5biy3ja

24 November 2022

mapped directly with Wikidata item

PMCID

3137083

1 reference

6 August 2017

1 reference