(Q35125022)

6 August 2017

Selective targeting of TGF-β activation to treat fibroinflammatory airway disease (English)

1 reference

6 August 2017

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Lynne Murray

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

David J Erle

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

author name string

Shunsuke Minagawa

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Jianlong Lou

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Anthony Cormier

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Shenping Wu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Yifan Cheng

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Ping Tsui

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Jane Connor

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Ronald Herbst

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Cedric Govaerts

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Tyren Barker

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Stephanie Cambier

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Haruhiko Yanagisawa

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Amanda Goodsell

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Mitsuo Hashimoto

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Oliver J Brand

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Ran Cheng

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Royce Ma

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Kate J McKnelly

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Weihua Wen

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Arthur Hill

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

David Jablons

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Paul Wolters

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Hideya Kitamura

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Jun Araya

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Andrea J Barczak

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Louis F Reichardt

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

James D Marks

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Jody L Baron

31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Stephen L Nishimura

32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

language of work or name

English

0 references

publication date

1 June 2014

1 reference

Science Translational Medicine

6 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

issue

241

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

page(s)

241ra79

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

9 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4341974/fullTextXML

inferred from PubMed Central ID database lookup

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/4341974

inferred from PubMed Central ID database lookup

cites work

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28 July 2018

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α(V)β(3) integrin crystal structures and their functional implications

28 July 2018

1 reference

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Crystal structure of α5β1 integrin ectodomain: Atomic details of the fibronectin receptor

28 July 2018

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IL-17A produced by αβ T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction

28 July 2018

1 reference

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Angiotensin receptor blockade attenuates cigarette smoke-induced lung injury and rescues lung architecture in mice

28 July 2018

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Regulation of integrin affinity on cell surfaces

28 July 2018

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P2X7 receptor and caspase 1 activation are central to airway inflammation observed after exposure to tobacco smoke

28 July 2018

1 reference

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Interleukin-1beta induces increased transcriptional activation of the transforming growth factor-beta-activating integrin subunit beta8 through altering chromatin architecture

28 July 2018

1 reference

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Chronic obstructive pulmonary disease exacerbations in the COPDGene study: associated radiologic phenotypes

28 July 2018

1 reference

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Latent TGF-β structure and activation

28 July 2018

1 reference

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Integrin structure, activation, and interactions

28 July 2018

1 reference

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Mesangial cell integrin αvβ8 provides glomerular endothelial cell cytoprotection by sequestering TGF-β and regulating PECAM-1

28 July 2018

1 reference

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TGF-β induces surface LAP expression on murine CD4 T cells independent of Foxp3 induction

28 July 2018

1 reference

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Requirement of open headpiece conformation for activation of leukocyte integrin alphaXbeta2.

28 July 2018

1 reference

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Modulation of integrin activation by an entropic spring in the {beta}-knee

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341974

Combined forced oscillation and forced expiration measurements in mice for the assessment of airway hyperresponsiveness

28 July 2018

1 reference

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Expression of the T helper 17-associated cytokines IL-17A and IL-17F in asthma and COPD.

28 July 2018

1 reference

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Recreation of the terminal events in physiological integrin activation

28 July 2018

1 reference

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Integrin alphaIIbbeta3 activation in Chinese hamster ovary cells and platelets increases clustering rather than affinity

28 July 2018

1 reference

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Integrin-mediated transforming growth factor-beta activation, a potential therapeutic target in fibrogenic disorders

28 July 2018

1 reference

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Crystal structure of the complete integrin αVβ3 ectodomain plus an α/β transmembrane fragment

28 July 2018

1 reference

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Homeostatic role of transforming growth factor-beta in the oral cavity and esophagus of mice and its expression by mast cells in these tissues

28 July 2018

1 reference

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Mice that lack activity of alphavbeta6- and alphavbeta8-integrins reproduce the abnormalities of Tgfb1- and Tgfb3-null mice

28 July 2018

1 reference

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Linking integrin conformation to function

28 July 2018

1 reference

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Cigarette smoke selectively enhances viral PAMP- and virus-induced pulmonary innate immune and remodeling responses in mice.

28 July 2018

1 reference

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Interleukin-1beta causes acute lung injury via alphavbeta5 and alphavbeta6 integrin-dependent mechanisms.

28 July 2018

1 reference

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Loss of integrin alpha(v)beta8 on dendritic cells causes autoimmunity and colitis in mice

28 July 2018

1 reference

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Using phage display to select antibodies recognizing post-translational modifications independently of sequence context

28 July 2018

1 reference

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Integrin-mediated transforming growth factor-beta activation regulates homeostasis of the pulmonary epithelial-mesenchymal trophic unit

28 July 2018

1 reference

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Remodeling in asthma and chronic obstructive pulmonary disease

28 July 2018

1 reference

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Molecular evolution of antibody affinity for sensitive detection of botulinum neurotoxin type A.

28 July 2018

1 reference

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The nature of small-airway obstruction in chronic obstructive pulmonary disease

28 July 2018

1 reference

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Negative staining and image classification — powerful tools in modern electron microscopy

28 July 2018

1 reference

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Loss of integrin alpha(v)beta6-mediated TGF-beta activation causes Mmp12-dependent emphysema

28 July 2018

1 reference

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Stabilizing the open conformation of the integrin headpiece with a glycan wedge increases affinity for ligand

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341974

beta8 integrins are required for vascular morphogenesis in mouse embryos

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341974

The integrin alpha(v)beta8 mediates epithelial homeostasis through MT1-MMP-dependent activation of TGF-beta1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341974

Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341974

Transient expression of IL-1beta induces acute lung injury and chronic repair leading to pulmonary fibrosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341974

Interactions between growth factors and integrins: latent forms of transforming growth factor-beta are ligands for the integrin alphavbeta1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341974

Parainfluenza virus-induced persistence of airway inflammation, fibrosis, and dysfunction associated with TGF-beta 1 expression in brown Norway rats

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341974

SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341974

Virus-induced airway hyperresponsiveness in man.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341974

Comparative protein modelling by satisfaction of spatial restraints

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341974

Integrin alpha v beta 8. Interaction with vitronectin and functional divergence of the beta 8 cytoplasmic domain

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341974

Cloning and expression of a divergent integrin subunit beta 8

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341974

Induction of heart valve lesions by small-molecule ALK5 inhibitors.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341974

Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8-mediated activation of TGF-β.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341974

Noninvasive and invasive pulmonary function in mouse models of obstructive and restrictive respiratory diseases

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341974

Imbalances between interleukin-1 and tumor necrosis factor agonists and antagonists in stable COPD.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341974

The role of interleukin-1beta in murine cigarette smoke-induced emphysema and small airway remodeling

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341974

Squamous metaplasia amplifies pathologic epithelial-mesenchymal interactions in COPD patients

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341974

Accumulation of dendritic cells and increased CCL20 levels in the airways of patients with chronic obstructive pulmonary disease.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341974

Respiratory syncytial virus, airway inflammation, and FEV1 decline in patients with chronic obstructive pulmonary disease.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341974

A 50-A separation of the integrin alpha v beta 3 extracellular domain C termini reveals an intermediate activation state

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341974

Allosteric beta1 integrin antibodies that stabilize the low affinity state by preventing the swing-out of the hybrid domain

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341974

Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341974

The Inhibitory Anti-β1 Integrin Monoclonal Antibody 13 Recognizes an Epitope That Is Attenuated by Ligand Occupancy

27 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3008074

Correlation of molecular shape with GPIIb-IIIa receptor antagonist activity in RGD peptides

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24944194

12 December 2020

inferred from PubMed ID database lookup

Correlation between serum biomarkers and BODE index in patients with stable COPD

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24944194

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1126/SCITRANSLMED.3008074

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24944194%20AND%20SRC:MED&resulttype=core&format=json