(Q35131769)

6 August 2017

Biochemical aspects of telomerase function (English)

1 reference

6 August 2017

Lea Harrington

1

1 reference

PubMed ID

12757972

6 August 2017

language of work or name

English

0 references

publication date

1 May 2003

1 reference

6 August 2017

1 reference

6 August 2017

194

1 reference

6 August 2017

139-154

1 reference

6 August 2017

2

1 reference

A tandemly repeated sequence at the termini of the extrachromosomal ribosomal RNA genes in Tetrahymena

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Elaboration of telomeres in yeast: recognition and modification of termini from Oxytricha macronuclear DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

DNA sequences of telomeres maintained in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Cloning yeast telomeres on linear plasmid vectors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Growth of chromosome ends in multiplying trypanosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Dynamics of telomere length variation in tetrahymena thermophila

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Functional Evidence for an RNA Template in Telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Inhibition of telomerase by G-quartet DNA structures

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Telomere terminal transferase activity from Euplotes crassus adds large numbers of TTTTGGGG repeats onto telomeric primers

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Identification of a nonprocessive telomerase activity from mouse cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

1 reference

7 January 2021

Telomerase activity in germline and embryonic cells of Xenopus.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Characterization and developmental patterns of telomerase expression in plants

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Specific association of human telomerase activity with immortal cells and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Chromosome structure in ciliated protozoans

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

t-loops at trypanosome telomeres.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Mammalian telomeres end in a large duplex loop

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Telomeres of polytene chromosomes in a ciliated protozoan terminate in duplex DNA loops

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Telomere length regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Purification of telomerase from Euplotes aediculatus: requirement of a primer 3' overhang

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Telomerase primer specificity and chromosome healing

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

A novel specificity for the primer-template pairing requirement in Tetrahymena telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Recognition of a chromosome truncation site associated with α-thalassaemia by human telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Utilization of ribonucleotides and RNA primers by Tetrahymena telomerase.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

A mutant of Tetrahymena telomerase reverse transcriptase with increased processivity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Tetrahymena telomerase catalyzes nucleolytic cleavage and nonprocessive elongation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Requirements for the dGTP-dependent repeat addition processivity of recombinant Tetrahymena telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

dGTP-dependent processivity and possible template switching of euplotes telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Euplotes telomerase: evidence for limited base-pairing during primer elongation and dGTP as an effector of translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

The anchor site of telomerase from Euplotes aediculatus revealed by photo-cross-linking to single- and double-stranded DNA primers

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

De novo telomere addition by Tetrahymena telomerase in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Sequence-specific DNA primer effects on telomerase polymerization activity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Telomerase is processive

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Functionally interacting telomerase RNAs in the yeast telomerase complex

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Telomerase-dependent repeat divergence at the 3' ends of yeast telomeres

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Progressive cis-inhibition of telomerase upon telomere elongation.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

A protein-counting mechanism for telomere length regulation in yeast.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Introduction of extra telomeric DNA sequences into Saccharomyces cerevisiae results in telomere elongation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

The C terminus of the major yeast telomere binding protein Rap1p enhances telomere formation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Varying the number of telomere-bound proteins does not alter telomere length in tel1Delta cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

The yeast telomere length counting machinery is sensitive to sequences at the telomere-nontelomere junction.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

A novel Rap1p-interacting factor, Rif2p, cooperates with Rif1p to regulate telomere length in Saccharomyces cerevisiae.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Telomere formation by rap1p binding site arrays reveals end-specific length regulation requirements and active telomeric recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Control of telomere length by the human telomeric protein TRF1

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Control of human telomere length by TRF1 and TRF2

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Switching and signaling at the telomere

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Gel shift and UV cross-linking analysis of Tetrahymena telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Developmentally regulated initiation of DNA synthesis by telomerase: evidence for factor-assisted de novo telomere formation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Processing of nontelomeric 3' ends by telomerase: default template alignment and endonucleolytic cleavage

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

The reverse transcriptase component of the Tetrahymena telomerase ribonucleoprotein complex

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Characterization of the interaction between the nuclease and reverse transcriptase activity of the yeast telomerase complex

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

TLC1: template RNA component of Saccharomyces cerevisiae telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Functional characterization and developmental regulation of mouse telomerase RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

The RNA component of human telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Architecture of telomerase RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Telomerase RNAs of different ciliates have a common secondary structure and a permuted template

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

A conserved secondary structure for telomerase RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Ciliate telomerase RNA structural features

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

A conserved pseudoknot in telomerase RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Secondary structure of vertebrate telomerase RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Functional reconstitution of wild-type and mutant Tetrahymena telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Boundary elements of the Tetrahymena telomerase RNA template and alignment domains

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Reconstitution of human telomerase activity and identification of a minimal functional region of the human telomerase RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Tetrahymena telomerase ribonucleoprotein RNA-protein interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Human telomerase RNA-protein interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Reconstitution of human telomerase activity in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Polymerization defects within human telomerase are distinct from telomerase RNA and TEP1 binding

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Functional multimerization of the human telomerase reverse transcriptase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

A stem-loop of Tetrahymena telomerase RNA distant from the template potentiates RNA folding and telomerase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Mutational analysis of the Tetrahymena telomerase RNA: identification of residues affecting telomerase activity in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Telomerase RNA function in recombinant Tetrahymena telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Template boundary definition in Tetrahymena telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

The telomerase RNA pseudoknot is critical for the stable assembly of a catalytically active ribonucleoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Altering specific telomerase RNA template residues affects active site function

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Specific RNA residue interactions required for enzymatic functions of Tetrahymena telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Template boundary in a yeast telomerase specified by RNA structure

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Telomerase recognizes its template by using an adjacent RNA motif

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Specific telomerase RNA residues distant from the template are essential for telomerase function

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Essential regions of Saccharomyces cerevisiae telomerase RNA: separate elements for Est1p and Est2p interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

The function of a stem-loop in telomerase RNA is linked to the DNA repair protein Ku.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Analysis of the structure of human telomerase RNA in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Functional regions of human telomerase reverse transcriptase and human telomerase RNA required for telomerase activity and RNA-protein interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Identification of Functional Domains and Dominant Negative Mutations in Vertebrate Telomerase RNA Using anin VivoReconstitution System

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Human telomerase activation requires two independent interactions between telomerase RNA and telomerase reverse transcriptase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

A critical stem-loop structure in the CR4-CR5 domain of mammalian telomerase RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Identification of an essential proximal sequence element in the promoter of the telomerase RNA gene of Tetrahymena thermophila

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

The mouse telomerase RNA 5"-end lies just upstream of the telomerase template sequence

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Method for determining RNA 3' ends and application to human telomerase RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

The product of the survival of motor neuron (SMN) gene is a human telomerase-associated protein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Telomere maintenance in telomerase-deficient mouse embryonic stem cells: characterization of an amplified telomeric DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Expression of mutant telomerase in immortal telomerase-negative human cells results in cell cycle deregulation, nuclear and chromosomal abnormalities and rapid loss of viability

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Transient expression of wild-type or biologically inactive telomerase allows the formation of artificial telomeres in mortal human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Block in anaphase chromosome separation caused by a telomerase template mutation.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Runaway telomere elongation caused by telomerase RNA gene mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Telomere fusions caused by mutating the terminal region of telomeric DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Uncapping and deregulation of telomeres lead to detrimental cellular consequences in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Biogenesis of yeast telomerase depends on the importin mtr10

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

In vitro assembly of human H/ACA small nucleolar RNPs reveals unique features of U17 and telomerase RNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

A box H/ACA small nucleolar RNA-like domain at the human telomerase RNA 3' end

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Very short telomeres in the peripheral blood of patients with X-linked and autosomal dyskeratosis congenita

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Purification of Tetrahymena telomerase and cloning of genes encoding the two protein components of the enzyme.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Reverse transcriptase motifs in the catalytic subunit of telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

The catalytic subunit of yeast telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Telomerase catalytic subunit homologs from fission yeast and human

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Human telomerase contains evolutionarily conserved catalytic and structural subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Two telomerase reverse transcriptases (TERTs) expressed in Candida albicans

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Telomerase reverse transcriptase genes identified in Tetrahymena thermophila and Oxytricha trifallax

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Disruption of the telomerase catalytic subunit gene from Arabidopsis inactivates telomerase and leads to a slow loss of telomeric DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Expression of mouse telomerase catalytic subunit in embryos and adult tissues.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Putative telomerase catalytic subunits from Giardia lamblia and Caenorhabditis elegans.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

The telomerase reverse transcriptase is limiting and necessary for telomerase function in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Presence of telomeric G-strand tails in the telomerase catalytic subunit TERT knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Preferential maintenance of critically short telomeres in mammalian cells heterozygous for mTert.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

The human telomerase catalytic subunit hTERT: organization of the gene and characterization of the promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

The hTERTalpha splice variant is a dominant negative inhibitor of telomerase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Induction of hTERT expression and telomerase activity by estrogens in human ovary epithelium cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Telomerase activity and expression of telomerase RNA component and catalytic subunits in precancerous and cancerous colorectal lesions

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Regulation of telomerase by alternate splicing of human telomerase reverse transcriptase (hTERT) in normal and neoplastic ovary, endometrium and myometrium

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Tissue-specific alternate splicing of human telomerase reverse transcriptase (hTERT) influences telomere lengths during human development

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Tamoxifen regulates human telomerase reverse transcriptase (hTERT) gene expression differently in breast and endometrial cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Direct activation of TERT transcription by c-MYC.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Regulation of the human telomerase reverse transcriptase gene

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Histone deacetylation is involved in the transcriptional repression of hTERT in normal human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Identification and characterization of negative regulatory elements of the human telomerase catalytic subunit (hTERT) gene promoter: possible role of MZF-2 in transcriptional repression of hTERT.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Telomerase activation by histone deacetylase inhibitor in normal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Human telomerase contains two cooperating telomerase RNA molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Telomerase activity reconstituted in vitro with purified human telomerase reverse transcriptase and human telomerase RNA component.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Functional reconstitution of human telomerase expressed in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

RNA binding domain of telomerase reverse transcriptase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Analysis of telomerase catalytic subunit mutants in vivo and in vitro in Schizosaccharomycespombe

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Template definition by Tetrahymena telomerase reverse transcriptase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Telomerase RNA bound by protein motifs specific to telomerase reverse transcriptase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Essential functions of amino-terminal domains in the yeast telomerase catalytic subunit revealed by selection for viable mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

N-terminal domains of the human telomerase catalytic subunit required for enzyme activity in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Functional analysis of conserved residues in the putative "finger" domain of telomerase reverse transcriptase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Identification of functionally important domains in the N-terminal region of telomerase reverse transcriptase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

The nucleolar localization domain of the catalytic subunit of human telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

C-terminal regions of the human telomerase catalytic subunit essential for in vivo enzyme activity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Analysis of telomerase processivity: mechanistic similarity to HIV-1 reverse transcriptase and role in telomere maintenance

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Two independent regions of human telomerase reverse transcriptase are important for its oligomerization and telomerase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Functional multimerization of human telomerase requires an RNA interaction domain in the N terminus of the catalytic subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Two inactive fragments of the integral RNA cooperate to assemble active telomerase with the human protein catalytic subunit (hTERT) in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

The telomerase reverse transcriptase: components and regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Interactions between telomerase and primase physically link the telomere and chromosome replication machinery

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

One-step affinity purification protocol for human telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

The Tetrahymena p80/p95 complex is required for proper telomere length maintenance and micronuclear genome stability.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Interaction of recombinant Tetrahymena telomerase proteins p80 and p95 with telomerase RNA and telomeric DNA substrates

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Tetrahymena proteins p80 and p95 are not core telomerase components

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

TLP1: a gene encoding a protein component of mammalian telomerase is a novel member of WD repeats family

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

A mammalian telomerase-associated protein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Vaults and telomerase share a common subunit, TEP1

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

The Telomerase/vault-associated protein TEP1 is required for vault RNA stability and its association with the vault particle

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Telomerase-associated protein TEP1 is not essential for telomerase activity or telomere length maintenance in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Euplotes telomerase contains an La motif protein produced by apparent translational frameshifting

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

The La antigen associates with the human telomerase ribonucleoprotein and influences telomere length in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Telomere elongation by hnRNP A1 and a derivative that interacts with telomeric repeats and telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

hnRNP A1 may interact simultaneously with telomeric DNA and the human telomerase RNA in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Heterogeneous nuclear ribonucleoproteins C1 and C2 associate with the RNA component of human telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Heterogeneous nuclear ribonucleoprotein A1 and UP1 protect mammalian telomeric repeats and modulate telomere replication in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Interaction of hnRNP A2/B1 isoforms with telomeric ssDNA and the in vitro function

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

In vitro properties of the conserved mammalian protein hnRNP D suggest a role in telomere maintenance

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

A model for heterogeneous nuclear ribonucleoproteins in telomere and telomerase regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Identification of two RNA-binding proteins associated with human telomerase RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Involvement of 14-3-3 proteins in nuclear localization of telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Stable association of hsp90 and p23, but Not hsp70, with active human telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Functional requirement of p23 and Hsp90 in telomerase complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Hsp90 levels affect telomere length in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Regulation of the hTERT telomerase catalytic subunit by the c-Abl tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

TERT regulates cell survival independent of telomerase enzymatic activity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Akt protein kinase enhances human telomerase activity through phosphorylation of telomerase reverse transcriptase subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Telomerase is controlled by protein kinase Calpha in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Molecular interactions between telomerase and the tumor suppressor protein p53 in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Protein phosphatase 2A inhibits nuclear telomerase activity in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Three Ever Shorter Telomere (EST) genes are dispensable for in vitro yeast telomerase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

The Est3 protein is a subunit of yeast telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Est1 has the properties of a single-stranded telomere end-binding protein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

The Est1 subunit of yeast telomerase binds the Tlc1 telomerase RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Association of the Est1 protein with telomerase activity in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Cdc13 delivers separate complexes to the telomere for end protection and replication

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Est1 and Cdc13 as comediators of telomerase access

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Cdc13 cooperates with the yeast Ku proteins and Stn1 to regulate telomerase recruitment

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Est1p as a cell cycle-regulated activator of telomere-bound telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Coordinate regulation of G- and C strand length during new telomere synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Specific DNA replication mutations affect telomere length in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Flexible filaments in a flowing soap film as a model for one-dimensional flags in a two-dimensional wind.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

The function of DNA polymerase alpha at telomeric G tails is important for telomere homeostasis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Characterization of genetic interactions with RFA1: the role of RPA in DNA replication and telomere maintenance.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Cell cycle restriction of telomere elongation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Saccharomyces telomeres acquire single-strand TG1-3 tails late in S phase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Evidence for a new step in telomere maintenance

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Exonuclease activity is required for sequence addition and Cdc13p loading at a de novo telomere

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

The role of the Mre11-Rad50-Xrs2 complex in telomerase- mediated lengthening of Saccharomyces cerevisiae telomeres

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Processing of telomeric DNA ends requires the passage of a replication fork

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Yeast Ku as a regulator of chromosomal DNA end structure

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Telomere maintenance is dependent on activities required for end repair of double-strand breaks.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Maintenance of double-stranded telomeric repeats as the critical determinant for cell viability in yeast cells lacking Ku.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

Yeast Ku protein plays a direct role in telomeric silencing and counteracts inhibition by rif proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900701-2

7 January 2021

10.1016/S0304-3835(02)00701-2

Identifiers

DOI

1 reference

6 August 2017

1 reference

PubMed ID

12757972