(Q35134632)

6 August 2017

title

Brain 5-HT deficiency increases stress vulnerability and impairs antidepressant responses following psychosocial stress (English)

1 reference

6 August 2017

3

Marc G Caron

1 reference

6 August 2017

Benjamin D Sachs

1

1 reference

6 August 2017

Jason R Ni

series ordinal

2

1 reference

6 August 2017

language of work or name

English

0 references

publication date

9 February 2015

1 reference

Proceedings of the National Academy of Sciences of the United States of America

6 August 2017

published in

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6 August 2017

volume

112

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6 August 2017

issue

8

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6 August 2017

page(s)

2557-2562

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β-catenin mediates stress resilience through Dicer1/microRNA regulation

6 August 2017

cites work

1 reference

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13 July 2018

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Prefrontal cortex reactivity underlies trait vulnerability to chronic social defeat stress

13 July 2018

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Prefrontal cortical circuit for depression- and anxiety-related behaviors mediated by cholecystokinin: role of ΔFosB.

13 July 2018

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Sex differences in response to chronic mild stress and congenital serotonin deficiency

13 July 2018

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Anxiolytic function of the orexin 2/hypocretin A receptor in the basolateral amygdala

13 July 2018

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DREADDs: novel tools for drug discovery and development

13 July 2018

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Congenital brain serotonin deficiency leads to reduced ethanol sensitivity and increased ethanol consumption in mice

13 July 2018

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βCaMKII in lateral habenula mediates core symptoms of depression

13 July 2018

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The effects of congenital brain serotonin deficiency on responses to chronic fluoxetine

13 July 2018

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A new translational target for deep brain stimulation to treat depression

13 July 2018

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The effects of brain serotonin deficiency on behavioural disinhibition and anxiety-like behaviour following mild early life stress

13 July 2018

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Cortical-amygdalar circuit dysfunction in a genetic mouse model of serotonin deficiency

13 July 2018

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Chronic SSRI treatment exacerbates serotonin deficiency in humanized Tph2 mutant mice

13 July 2018

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Cortical control of affective networks

13 July 2018

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DREADDing the lateral habenula: a review of methodological approaches for studying lateral habenula function

13 July 2018

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The 5-HT deficiency theory of depression: perspectives from a naturalistic 5-HT deficiency model, the tryptophan hydroxylase 2Arg439His knockin mouse

13 July 2018

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Activation of lateral habenula inputs to the ventral midbrain promotes behavioral avoidance

13 July 2018

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Input to the lateral habenula from the basal ganglia is excitatory, aversive, and suppressed by serotonin.

13 July 2018

1 reference

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A role for repressive histone methylation in cocaine-induced vulnerability to stress

13 July 2018

1 reference

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A novel role of the WNT-dishevelled-GSK3β signaling cascade in the mouse nucleus accumbens in a social defeat model of depression

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345581

Deficient serotonin neurotransmission and depression-like serotonin biomarker alterations in tryptophan hydroxylase 2 (Tph2) loss-of-function mice

13 July 2018

1 reference

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Synaptic potentiation onto habenula neurons in the learned helplessness model of depression

13 July 2018

1 reference

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Remission of major depression under deep brain stimulation of the lateral habenula in a therapy-refractory patient

13 July 2018

1 reference

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The effects of tryptophan depletion on neural responses to emotional words in remitted depression

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345581

Representation of negative motivational value in the primate lateral habenula

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345581

Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345581

Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345581

Lateral habenula as a source of negative reward signals in dopamine neurons

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345581

Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345581

Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345581

SNP and haplotype analysis of a novel tryptophan hydroxylase isoform (TPH2) gene provide evidence for association with major depression

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345581

Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345581

The influence of genetic factors and life stress on depression among adolescent girls

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345581

Social model of depression in mice of C57BL/6J strain

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345581

5HT(1B) receptor-mediated pre-synaptic depression of excitatory inputs to the rat lateral habenula

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345581

Functionally altered neurocircuits in a rat model of treatment-resistant depression show prominent role of the habenula

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345581

Tryptophan hydroxylase 2 gene polymorphisms and poststroke anxiety disorders.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345581

Pharmacological inhibition of the lateral habenula improves depressive-like behavior in an animal model of treatment resistant depression.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345581

Tryptophan hydroxylase 2 gene is associated with major depression and antidepressant treatment response

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345581

Common genetic variations in human brain-specific tryptophan hydroxylase-2 and response to antidepressant treatment

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345581

Haplotype-based linkage of tryptophan hydroxylase 2 to suicide attempt, major depression, and cerebrospinal fluid 5-hydroxyindoleacetic acid in 4 populations

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345581

Investigation of serotonin-related genes in antidepressant response

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345581

Genetic moderation of environmental risk for depression and anxiety in adolescent girls.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345581

27 September 2018

Identifiers

DOI

10.1073/PNAS.1416866112

1 reference

6 August 2017

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1 reference

6 August 2017

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