(Q35146545)

6 August 2017

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title

Human melanocyte senescence and melanoma susceptibility genes (English)

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6 August 2017

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Dorothy C Bennett

1

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6 August 2017

language of work or name

English

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publication date

1 May 2003

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6 August 2017

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6 August 2017

volume

22

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6 August 2017

issue

20

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6 August 2017

page(s)

3063-3069

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Id1 regulation of cellular senescence through transcriptional repression of p16/Ink4a.

6 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

A critical role for telomeres in suppressing and facilitating carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

The human melanocyte: a model system to study the complexity of cellular aging and transformation in non-fibroblastic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

The melanocortin-1-receptor gene is the major freckle gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Mechanisms of differentiation in melanoma cells and melanocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Molecular regulation of melanocyte senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Telomere states and cell fates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

INK4a-deficient human diploid fibroblasts are resistant to RAS-induced senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Cyclic AMP a key messenger in the regulation of skin pigmentation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Model predicting survival in stage I melanoma based on tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Mutations of the BRAF gene in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Protein tyrosine kinases in malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Selective proliferation of normal human melanocytes in vitro in the presence of phorbol ester and cholera toxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Activation of a cAMP pathway and induction of melanogenesis correlate with association of p16(INK4) and p27(KIP1) to CDKs, loss of E2F-binding activity, and premature senescence of human melanocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Regulation of tyrosinase in human melanocytes grown in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Deregulated E2F transcriptional activity in autonomously growing melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Update on genetic events in the pathogenesis of melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

New developments in melanoma genetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Expression of the tumor suppressor gene product p16INK4 in benign and malignant melanocytic lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

PIG3V, an immortalized human vitiligo melanocyte cell line, expresses dilated endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Terminal differentiation and senescence in the human melanocyte: repression of tyrosine-phosphorylation of the extracellular signal-regulated kinase 2 selectively defines the two phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

A melanoma-associated germline mutation in exon 1beta inactivates p14ARF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

p16(MTS-1/CDKN2/INK4a) in cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Telomerase activity in melanocytic lesions: A potential marker of tumor biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Role of the INK4a locus in tumor suppression and cell mortality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

The INK4A/ARF locus and its two gene products

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

The INK4a/ARF network in tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Differentiation of human melanoma cells through p38 MAP kinase is associated with decreased retinoblastoma protein phosphorylation and cell cycle arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

p16(Ink4a) in melanocyte senescence and differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

p16/cyclin-dependent kinase inhibitor 2A deficiency in human melanocyte senescence, apoptosis, and immortalization: possible implications for melanoma progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Virtually 100% of melanoma cell lines harbor alterations at the DNA level within CDKN2A, CDKN2B, or one of their downstream targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Role of p14(ARF) in replicative and induced senescence of human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Melanocyte-stimulating hormone promotes activation of pre-existing tyrosinase molecules in Cloudman S91 melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Reduced growth factor requirements and accelerated cell-cycle kinetics in adult human melanocytes transformed with SV40 large T antigen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Melanocortin 1 Receptor (MC1R) Gene Variants are Associated with an Increased Risk for Cutaneous Melanoma Which is Largely Independent of Skin Type and Hair Color

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Mutations in theINK4a/ARFMelanoma Susceptibility Locus Functionally Impair p14ARF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

Selective cultivation of human melanocytes from newborn and adult epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

7 January 2021

Increase in telomerase activity during progression of melanocytic cells from melanocytic naevi to malignant melanomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

7 January 2021

In vitro growth patterns of normal human melanocytes and melanocytes from different stages of melanoma progression

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

7 January 2021

Human melanocytes cultured from nevi and melanomas

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206446

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206446

1 reference

6 August 2017

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