(Q35146572)

6 August 2017

1 reference

title

PTEN signaling pathways in melanoma (English)

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6 August 2017

Heng Wu

1

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6 August 2017

Vikas Goel

series ordinal

2

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6 August 2017

Frank G Haluska

series ordinal

3

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6 August 2017

language of work or name

English

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publication date

1 May 2003

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6 August 2017

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6 August 2017

volume

22

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6 August 2017

issue

20

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6 August 2017

page(s)

3113-3122

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1206451

6 August 2017

exact match

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cites work

Cell cycle arrest and astrocytic differentiation resulting from PTEN expression in glioma cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Mutation and allelic loss of the PTEN/MMAC1 gene in primary and metastatic melanoma biopsies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

The PTEN tumour suppressor gene and malignant melanoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Mutations of the human PTEN gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

PTEN expression is reduced in a subset of sporadic thyroid carcinomas: evidence that PTEN-growth suppressing activity in thyroid cancer cells mediated by p27kip1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Frequency of homozygous deletion at p16/CDKN2 in primary human tumours

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Identification of PTEN mutations in metastatic melanoma specimens

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Cooperative effects of INK4a and ras in melanoma susceptibility in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Mutations of the BRAF gene in human cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

The multiple roles of PTEN in tumor suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Pten is essential for embryonic development and tumour suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Deletion mapping of the long arm of chromosome 10 in glioblastoma multiforme

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

PTEN transcriptionally modulates c-myc gene expression in human breast carcinoma cells and is involved in cell growth regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Differential nuclear and cytoplasmic expression of PTEN in normal thyroid tissue, and benign and malignant epithelial thyroid tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Shc and FAK differentially regulate cell motility and directionality modulated by PTEN.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Molecular genetics of familial cutaneous melanoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Loss of heterozygosity in sporadic primary cutaneous melanoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

PTEN induces chemosensitivity in PTEN-mutated prostate cancer cells by suppression of Bcl-2 expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Suppression of tumorigenicity and metastasis in B16F10 cells by PTEN/MMAC1/TEP1 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Cytogenetic homogeneity in eight independent sites in a case of malignant melanoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Somatic mutations of the PTEN/MMAC1 gene in fifteen Japanese endometrial cancers: evidence for inactivation of both alleles.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

PTEN regulates the ubiquitin-dependent degradation of the CDK inhibitor p27(KIP1) through the ubiquitin E3 ligase SCF(SKP2)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Glial cell line-derived neurotrophic factor-stimulated phosphatidylinositol 3-kinase and Akt activities exert opposing effects on the ERK pathway: importance for the rescue of neuroectodermic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Phosphatase and tensin analog gene overexpression engenders cellular death in human malignant mesothelioma cells via inhibition of AKT phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Germline mutations in the PTEN/MMAC1 gene in patients with Cowden disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

The protein kinase B/Akt signalling pathway in human malignancy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Possible involvement of the chromosome region 10q24----q26 in early stages of melanocytic neoplasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Stem cells. PTEN--coupling tumor suppression to stem cells?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

PTEN/MMAC1 in malignant melanoma and its importance for tumor progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Detection of new PTEN/MMAC1 mutations in head and neck squamous cell carcinomas with loss of chromosome 10.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Allelic losses on chromosome arm 10q and mutation of the PTEN (MMAC1) tumour suppressor gene in primary and metastatic malignant melanomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

In vitro loss of heterozygosity targets the PTEN/MMAC1 gene in melanoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Recent advances in melanoma research

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

From form to function: signaling by protein tyrosine phosphatases.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Identification of PTEN/MMAC1 alterations in uncultured melanomas and melanoma cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

PTEN induces apoptosis and cell cycle arrest through phosphoinositol-3-kinase/Akt-dependent and -independent pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

PTEN coordinates G(1) arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase activity in a breast cancer model

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Transient ectopic expression of PTEN in thyroid cancer cell lines induces cell cycle arrest and cell type-dependent cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

PTEN inhibits insulin-stimulated MEK/MAPK activation and cell growth by blocking IRS-1 phosphorylation and IRS-1/Grb-2/Sos complex formation in a breast cancer model

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Nuclear PTEN expression and clinicopathologic features in a population-based series of primary cutaneous melanoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Transcriptional activation of p21WAF1 by PTEN/MMAC1 tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Genetic analysis of Pten and Ink4a/Arf interactions in the suppression of tumorigenesis in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

PTEN sensitizes prostate cancer cells to death receptor-mediated and drug-induced apoptosis through a FADD-dependent pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Crystal structure of the dual specificity protein phosphatase VHR

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Epigenetic PTEN silencing in malignant melanomas without PTEN mutation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206451

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206451

1 reference

Dimensions Publication ID

6 August 2017

1038108476

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1 reference