(Q43701623)

26 November 2017

PTEN induces chemosensitivity in PTEN-mutated prostate cancer cells by suppression of Bcl-2 expression (English)

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26 November 2017

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H Huang

1

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26 November 2017

J C Cheville

2

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26 November 2017

Y Pan

3

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26 November 2017

P C Roche

4

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26 November 2017

L J Schmidt

5

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26 November 2017

D J Tindall

6

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26 November 2017

language of work or name

English

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publication date

8 August 2001

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Journal of Biological Chemistry

26 November 2017

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26 November 2017

276

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26 November 2017

38830-38836

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26 November 2017

42

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International trends and patterns of prostate cancer incidence and mortality

26 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

A controlled trial of leuprolide with and without flutamide in prostatic carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

Mutational spectra of PTEN/MMAC1 gene: a tumor suppressor with lipid phosphatase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

Cellular survival: a play in three Akts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

The multiple roles of PTEN in tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

CREB is a regulatory target for the protein kinase Akt/PKB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

Akt/protein kinase B up-regulates Bcl-2 expression through cAMP-response element-binding protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

Induction of bcl-2 expression by phosphorylated CREB proteins during B-cell activation and rescue from apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

Insulin-like growth factor-I induces bcl-2 promoter through the transcription factor cAMP-response element-binding protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

The Bcl-2 protein family: arbiters of cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

Phosphorylation of ETS transcription factor ER81 in a complex with its coactivators CREB-binding protein and p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

Mechanisms of transcriptional activation of bcl-2 gene expression by 17beta-estradiol in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

Inhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

Bcl-2 promotes regeneration of severed axons in mammalian CNS

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

WT1 modulates apoptosis by transcriptionally upregulating the bcl-2 proto-oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

Involvement of microtubules in the regulation of Bcl2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

PIK3CA is implicated as an oncogene in ovarian cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

Increased AKT activity contributes to prostate cancer progression by dramatically accelerating prostate tumor growth and diminishing p27Kip1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

Combination adriamycin and suramin induces apoptosis in bcl-2 expressing prostate carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

Signaling network of paclitaxel-induced apoptosis in the LNCaP prostate cancer cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

A recombinant defective adenoviral agent expressing anti-bcl-2 ribozyme promotes apoptosis of bcl-2-expressing human prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

MMAC1/PTEN inhibits cell growth and induces chemosensitivity to doxorubicin in human bladder cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

PTEN gene transfer in human malignant glioma: sensitization to irradiation and CD95L-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

BRCA1 Facilitates Stress-induced Apoptosis in Breast and Ovarian Cancer Cell Lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103632200

21 January 2018

Identifiers

DOI

10.1074/JBC.M103632200

1 reference

26 November 2017

1 reference