(Q35158006)

6 August 2017

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title

Making better drugs: Decision gates in non-clinical drug development (English)

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6 August 2017

J Fred Pritchard

1

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6 August 2017

Malle Jurima-Romet

2

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6 August 2017

Mark L J Reimer

3

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6 August 2017

Elisabeth Mortimer

4

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6 August 2017

Brenda Rolfe

5

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6 August 2017

Mitchell N Cayen

6

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6 August 2017

publication date

1 July 2003

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Nature Reviews Drug Discovery

6 August 2017

published in

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6 August 2017

volume

2

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6 August 2017

issue

7

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6 August 2017

page(s)

542-553

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https://scigraph.springernature.com/pub.10.1038/nrd1131

6 August 2017

exact match

0 references

cites work

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Linking a genetic defect to its cellular phenotype in a cardiac arrhythmia

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HERG K(+) channel activity is regulated by changes in phosphatidyl inositol 4,5-bisphosphate

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HERG channel dysfunction in human long QT syndrome. Intracellular transport and functional defects

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Toxicogenomics and drug discovery: will new technologies help us produce better drugs?

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31 March 2020

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Nuclear Magnetic Resonance Spectroscopic and Principal Components Analysis Investigations into Biochemical Effects of Three Model Hepatotoxins

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31 March 2020

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31 March 2020

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31 March 2020

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CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes

31 March 2020

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An Introduction to Quadrupole Ion Trap Mass Spectrometry

31 March 2020

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An introduction to quadrupole-time-of-flight mass spectrometry

31 March 2020

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Liquid chromatography-nuclear magnetic resonance spectroscopy

31 March 2020

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Primary hepatocyte cultures as an in vitro experimental model for the evaluation of pharmacokinetic drug-drug interactions

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRD1131

1 reference

6 August 2017

1 reference