(Q35160636)

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NbIT--a new information theory-based analysis of allosteric mechanisms reveals residues that underlie function in the leucine transporter LeuT.

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24785005%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

NbIT--a new information theory-based analysis of allosteric mechanisms reveals residues that underlie function in the leucine transporter LeuT (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24785005%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Michael V. LeVine

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24785005%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Harel Weinstein

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24785005%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

author name string

Michael V LeVine

1

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Europe PubMed Central

6 August 2017

Harel Weinstein

2

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Europe PubMed Central

6 August 2017

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1 May 2014

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Europe PubMed Central

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17 March 2020

PLOS Computational Biology

1 reference

Europe PubMed Central

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17 March 2020

10

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17 March 2020

5

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Europe PubMed Central

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17 March 2020

e1003603

1 reference

Europe PubMed Central

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17 March 2020

copyright license

Creative Commons Attribution 4.0 International

1 May 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Mechanistic picture for conformational transition of a membrane transporter at atomic resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

13 July 2018

Structural basis for action by diverse antidepressants on biogenic amine transporters

1 reference

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13 July 2018

The membrane protein LeuT in micellar systems: aggregation dynamics and detergent binding to the S2 site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

13 July 2018

Coupled global and local changes direct substrate translocation by neurotransmitter-sodium symporter ortholog LeuT.

1 reference

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13 July 2018

Simulations of biased agonists in the β(2) adrenergic receptor with accelerated molecular dynamics

1 reference

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13 July 2018

Ligand induced conformational changes of the human serotonin transporter revealed by molecular dynamics simulations

1 reference

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13 July 2018

The cost of living in the membrane: a case study of hydrophobic mismatch for the multi-segment protein LeuT.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

13 July 2018

Allosteric networks in thrombin distinguish procoagulant vs. anticoagulant activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

13 July 2018

Exploring residue component contributions to dynamical network models of allostery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

13 July 2018

Role of detergents in conformational exchange of a G protein-coupled receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

13 July 2018

Substrate binds in the S1 site of the F253A mutant of LeuT, a neurotransmitter sodium symporter homologue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

13 July 2018

Experimental conditions can obscure the second high-affinity site in LeuT.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

13 July 2018

X-ray structures of LeuT in substrate-free outward-open and apo inward-open states

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

13 July 2018

Insights into transport mechanism from LeuT engineered to transport tryptophan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

13 July 2018

Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

13 July 2018

The substrate-driven transition to an inward-facing conformation in the functional mechanism of the dopamine transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

13 July 2018

Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

13 July 2018

Ion/substrate-dependent conformational dynamics of a bacterial homolog of neurotransmitter:sodium symporters.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

13 July 2018

Update of the CHARMM all-atom additive force field for lipids: validation on six lipid types

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

13 July 2018

Single-molecule dynamics of gating in a neurotransmitter transporter homologue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

13 July 2018

CHARMM: the biomolecular simulation program

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

13 July 2018

Long-range coupling in an allosteric receptor revealed by mutant cycle analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

13 July 2018

Dynamical networks in tRNA:protein complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

13 July 2018

Binding of an octylglucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

13 July 2018

Location of the antidepressant binding site in the serotonin transporter: importance of Ser-438 in recognition of citalopram and tricyclic antidepressants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

13 July 2018

A competitive inhibitor traps LeuT in an open-to-out conformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

13 July 2018

An intracellular interaction network regulates conformational transitions in the dopamine transporter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

13 July 2018

Substrate binding and formation of an occluded state in the leucine transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

13 July 2018

Signal propagation in proteins and relation to equilibrium fluctuations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

13 July 2018

Antidepressant binding site in a bacterial homologue of neurotransmitter transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

13 July 2018

Residues crucial for maintaining short paths in network communication mediate signaling in proteins

1 reference

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13 July 2018

Scalable molecular dynamics with NAMD

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

13 July 2018

Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

13 July 2018

Is allostery an intrinsic property of all dynamic proteins?

1 reference

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13 July 2018

Allosteric proteins and cellular control systems

1 reference

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Simple Allosteric Model for Membrane Pumps

1 reference

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13 July 2018

Neurotransmitter/sodium symporter orthologue LeuT has a single high-affinity substrate site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

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Multivariate dependence and genetic networks inference.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006702

27 September 2018

The mechanism of a neurotransmitter:sodium symporter--inward release of Na+ and substrate is triggered by substrate in a second binding site

1 reference

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27 September 2018

Information Theoretical Analysis of Multivariate Correlation

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1003603

21 January 2018

Network Analysis of Protein Structures Identifies Functional Residues

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1003603

21 January 2018

Generalized correlation for biomolecular dynamics

1 reference

https://pubmed.ncbi.nlm.nih.gov/24785005

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comprehensive structure-based alignment of prokaryotic and eukaryotic neurotransmitter/Na+ symporters (NSS) aids in the use of the LeuT structure to probe NSS structure and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/24785005

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shedding light on protein-ligand binding by graph theory: the topological nature of allostery

1 reference

https://pubmed.ncbi.nlm.nih.gov/24785005

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Software news and updates. Carma: a molecular dynamics analysis program

1 reference

https://pubmed.ncbi.nlm.nih.gov/24785005

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inferred from PubMed ID database lookup

Physical nature of higher-order mutual information: intrinsic correlations and frustration

1 reference

https://pubmed.ncbi.nlm.nih.gov/24785005

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PCBI.1003603

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24785005%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

DBLP publication ID

journals/ploscb/LeVineW14

1 reference

DBLP Dataset 2021-01-02

28 January 2021

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24785005%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24785005%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

ResearchGate publication ID

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